Podcast
Questions and Answers
What is the most common cause of lumbar radiculopathy?
What is the most common cause of lumbar radiculopathy?
Which of the following conditions is considered serious and emergent, requiring rapid treatment?
Which of the following conditions is considered serious and emergent, requiring rapid treatment?
What is the primary difference between mechanical and degenerative causes of low back pain?
What is the primary difference between mechanical and degenerative causes of low back pain?
Which of the following is an example of an inflammatory cause of low back pain?
Which of the following is an example of an inflammatory cause of low back pain?
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What is the primary concern when evaluating a patient with acute low back pain and radiculopathy?
What is the primary concern when evaluating a patient with acute low back pain and radiculopathy?
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Which of the following is an example of a visceral disease that can cause low back pain?
Which of the following is an example of a visceral disease that can cause low back pain?
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What is the estimated prevalence of lumbosacral radiculopathy in the population?
What is the estimated prevalence of lumbosacral radiculopathy in the population?
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What is the most common type of lumbar radiculopathy?
What is the most common type of lumbar radiculopathy?
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What is the typical pain experience of patients with lumbosacral radiculopathy?
What is the typical pain experience of patients with lumbosacral radiculopathy?
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What is a risk factor for lumbosacral radiculopathy?
What is a risk factor for lumbosacral radiculopathy?
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What is an important aspect to assess during history intake for lumbosacral radiculopathy?
What is an important aspect to assess during history intake for lumbosacral radiculopathy?
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What is typically worse with increased intradiscal pressure in patients with lumbosacral radiculopathy?
What is typically worse with increased intradiscal pressure in patients with lumbosacral radiculopathy?
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What percentage of patients with lumbar disc herniation experience relief within 6-12 weeks without treatment?
What percentage of patients with lumbar disc herniation experience relief within 6-12 weeks without treatment?
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What is the characteristic of a bulging disc?
What is the characteristic of a bulging disc?
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What is the prognosis for a herniated disc - protrusion without treatment?
What is the prognosis for a herniated disc - protrusion without treatment?
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What is the characteristic of a herniated disc - extrusion?
What is the characteristic of a herniated disc - extrusion?
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What is the prognosis for a herniated disc - sequestration without treatment?
What is the prognosis for a herniated disc - sequestration without treatment?
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What is the significance of contralateral pain at less than 45o in a crossed SLR test?
What is the significance of contralateral pain at less than 45o in a crossed SLR test?
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In L5 radiculopathy, which of the following findings has the highest sensitivity?
In L5 radiculopathy, which of the following findings has the highest sensitivity?
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In S1 radiculopathy, which of the following is a common area of paresthesia/sensory change?
In S1 radiculopathy, which of the following is a common area of paresthesia/sensory change?
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In L5 radiculopathy, which of the following has a likelihood ratio (LR+) of 3.1?
In L5 radiculopathy, which of the following has a likelihood ratio (LR+) of 3.1?
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In S1 radiculopathy, which of the following reflexes is often absent?
In S1 radiculopathy, which of the following reflexes is often absent?
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In S1 radiculopathy, which of the following motor weakness is commonly seen?
In S1 radiculopathy, which of the following motor weakness is commonly seen?
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In L5 radiculopathy, which of the following has a likelihood ratio (LR-) of 0.7?
In L5 radiculopathy, which of the following has a likelihood ratio (LR-) of 0.7?
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What is the term for the degeneration of the vertebral bodies, joints, and foramina due to wear and tear?
What is the term for the degeneration of the vertebral bodies, joints, and foramina due to wear and tear?
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What is the condition characterized by the slippage of one vertebral body with respect to the adjacent vertebral body?
What is the condition characterized by the slippage of one vertebral body with respect to the adjacent vertebral body?
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What percentage of people between 60-69 years old have spinal stenosis?
What percentage of people between 60-69 years old have spinal stenosis?
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What is the term for weakness or stress fracture through the pars interarticularis?
What is the term for weakness or stress fracture through the pars interarticularis?
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What is the term for the age-related degeneration of the spinal column?
What is the term for the age-related degeneration of the spinal column?
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What is the symptom of spinal stenosis that depends on the affected nerve root?
What is the symptom of spinal stenosis that depends on the affected nerve root?
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What is a characteristic of a person with a panic disorder during a mental status examination?
What is a characteristic of a person with a panic disorder during a mental status examination?
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What is a common cognitive distortion in individuals with panic disorder?
What is a common cognitive distortion in individuals with panic disorder?
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What is a criterion for diagnosing panic disorder?
What is a criterion for diagnosing panic disorder?
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What is a common behavioral change in individuals with panic disorder?
What is a common behavioral change in individuals with panic disorder?
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What is a typical affective state in individuals with panic disorder?
What is a typical affective state in individuals with panic disorder?
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What is a question asked in the PHQ-PD module?
What is a question asked in the PHQ-PD module?
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What is the purpose of the PHQ-PD and ANS questionnaires?
What is the purpose of the PHQ-PD and ANS questionnaires?
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What is the sensitivity of the ANS questionnaire in identifying panic disorder?
What is the sensitivity of the ANS questionnaire in identifying panic disorder?
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What is adjustment disorder?
What is adjustment disorder?
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What is the prevalence of adjustment disorder in the general population?
What is the prevalence of adjustment disorder in the general population?
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What is the typical timeline for the onset and resolution of adjustment disorder?
What is the typical timeline for the onset and resolution of adjustment disorder?
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What is the prognosis for patients with adjustment disorder?
What is the prognosis for patients with adjustment disorder?
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What is the prevalence of other specified depressive disorder?
What is the prevalence of other specified depressive disorder?
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What is the duration of symptoms for a diagnosis of persistent depressive disorder (PDD)?
What is the duration of symptoms for a diagnosis of persistent depressive disorder (PDD)?
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What is the risk factor for other specified depressive disorder?
What is the risk factor for other specified depressive disorder?
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What is the prognosis for other specified depressive disorder?
What is the prognosis for other specified depressive disorder?
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What is the diagnostic criteria for PDD according to DSM-5?
What is the diagnostic criteria for PDD according to DSM-5?
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What is the management for other specified depressive disorder?
What is the management for other specified depressive disorder?
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What is the primary purpose of the PHQ-9 questionnaire?
What is the primary purpose of the PHQ-9 questionnaire?
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How often are individuals asked to rate their experiences in the PHQ-9 questionnaire?
How often are individuals asked to rate their experiences in the PHQ-9 questionnaire?
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What is the next question asked after the PHQ-9 item assessment?
What is the next question asked after the PHQ-9 item assessment?
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What is the scale used to rate the frequency of experiences in the PHQ-9 questionnaire?
What is the scale used to rate the frequency of experiences in the PHQ-9 questionnaire?
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How many items are assessed in the PHQ-9 questionnaire?
How many items are assessed in the PHQ-9 questionnaire?
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What is the purpose of the PHQ-9 questionnaire in a clinical setting?
What is the purpose of the PHQ-9 questionnaire in a clinical setting?
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What is the primary purpose of assessing the severity of disease in a patient's mental health assessment?
What is the primary purpose of assessing the severity of disease in a patient's mental health assessment?
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What is the term for the systematic review of a patient's mental status, including appearance, behavior, and thought processes?
What is the term for the systematic review of a patient's mental status, including appearance, behavior, and thought processes?
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Which of the following is an example of a subjective data point in a patient's mental health assessment?
Which of the following is an example of a subjective data point in a patient's mental health assessment?
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What is the purpose of using a screening tool, such as the GAD-7, in a patient's mental health assessment?
What is the purpose of using a screening tool, such as the GAD-7, in a patient's mental health assessment?
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What is the importance of assessing a patient's cognitive function, such as thought process and content, in a mental health assessment?
What is the importance of assessing a patient's cognitive function, such as thought process and content, in a mental health assessment?
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What is the term for the process of using sensitivity, specificity, and likelihood ratios to influence the threshold for diagnosis and treatment in medical decision making?
What is the term for the process of using sensitivity, specificity, and likelihood ratios to influence the threshold for diagnosis and treatment in medical decision making?
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Study Notes
Classification of LBP
- LBP due to mechanical spine problems: lumbar radiculopathy, spinal stenosis, cauda equina syndrome
- LBP due to systemic disease affecting the spine: neoplasms, infection, osteoporotic compression fracture, inflammatory arthritis
- LBP due to visceral disease: pelvic, renal, GI structures
Ddx of Acute LBP with Radiculopathy
- Mechanical: spinal fracture, lumbar disc herniation, cauda equina syndrome, piriformis syndrome, Iliotibial band syndrome
- Degenerative: spinal stenosis, spondylosis, spondylolisthesis, facet arthropathy, pseudoclaudication
- Inflammatory: sacroiliitis, greater trochanter bursitis, ankylosing spondylitis
- Oncologic: spinal neoplasms (most commonly metastatic)
- Infectious: vertebral lesion (infection, e.g. S1
Epidemiology of LBP with Radiculopathy
- Prevalence: 3-5% of population
- Male > female (3:2), especially in those over 40 and 50 years old respectively
- L5 radiculopathy is the single most common lumbar radiculopathy
- Pain experience: tingling, electric, burning or sharp, paresthesia (63-72%), radiation of pain into lower limb (35%), numbness (27%), muscle weakness (up to 37%), absent ankle reflexes (40%), absent knee reflexes (18%)
Risk Factors for LBP with Radiculopathy
- Social history: repetitive lifting and twisting motions, chronic overloading of disc, driving occupations, heavy industry work, military, smoking, overweight, sedentary lifestyle
- Medical history: prior trauma (fall, MVA), multiple pregnancies, history of back pain, chronic cough
History Intake for LBP with Radiculopathy
- Site: location of back pain
- Onset: how and when back pain developed
- Quality: throbbing, aching, sharp, dull, burning, pressure, numbness, tingling, or shooting
- Radiation: dermatomal distribution
- Time course: change in back pain over time
- Severity: scale of 1-10
- Pain is typically worse with: increased intradiscal pressure, Valsalva, weight bearing, standing, walking, sitting for prolonged periods
- Pain is typically better with: extension of the lumbar spine, recumbent position (knees flexed)
- Associated signs and symptoms: motor or sensory disturbances, saddle anaesthesia (if cauda equina syndrome is possible)
Patterns of Disc Herniation
- Bulging disc: loss/damage of annular fibers, associated with trauma, repetitive stress or aging, prognosis: regression (13%), complete disappearance (11%)
- Herniated disc - protrusion (prolapse): focal distension of the disc, annulus fibrosis remains intact, prognosis: regression (41%), complete disappearance (0%)
- Herniated disc - extrusion: nucleus palposus breaks through the annulus fibrosis, remains in the disc, prognosis: regression (70%), complete disappearance (15%)
- Herniated disc - sequestration: nucleus palposus breaks through the annulus fibrosis, displaced from the site of extrusion
L5 Radiculopathy
- Findings: weak hallux extension (sensitivity: 12-62%, LR+: 1.7, LR-: 0.7), weak ankle dorsiflexion, sensory loss in L5 distribution (sensitivity: 20-52%, LR+: 3.1, LR-: 0.8), asymmetric medial hamstring reflex (sensitivity: 57%, LR+: 6.2, LR-: 0.5)
S1 Radiculopathy
- Distribution of pain: sacral or buttock pain into the posterior aspect of the patient's leg, into the foot, or the perineum
- Physical exam: motor weakness: plantar flexion, paresthesia/sensory changes: sole, lateral foot and ankle, fourth and fifth toes, absent reflexes: ankle reflex (S1)
- Findings: weak ankle plantar flexion (sensitivity: 26-45%, LR+: NS, LR-: 0.7), ipsilateral calf wasting (sensitivity: 43%, LR+: 2.4, LR-: 0.7), sensory loss in S1 distribution (sensitivity: 32-49%, LR+: 2.4, LR-: 0.7), asymmetric achilles reflex (sensitivity: 45-91%, LR+: 2.7, LR-: 0.5)
Serious Disorders Affecting the Lumbar Spine
- Spondylosis: age-related degeneration of the spinal column (involves degenerative disc disease and facet arthropathy)
- Spinal stenosis: narrowing of the spinal canal, neural foramen and lateral recess, leading to compression of the nerve roots and neurogenic claudication
- Spondylolysis: weakness or stress fracture through the pars interarticularis
- Spondylolisthesis: slippage of one vertebral body with respect to the adjacent vertebral body
Panic Disorder
- Diagnostic criteria: recurrent, unexpected panic attacks with 4 or more of the following symptoms:
- Palpitations, pounding heart, or accelerated heart rate
- Sweating
- Trembling or shaking
- Sensations of shortness of breath or smothering
- Feelings of choking
- Chest pain or discomfort
- Nausea or abdominal distress
- Feeling dizzy, unsteady, light-headed, or faint
- Chills or heat sensations
- Paresthesias (numbness or tingling sensations)
- Derealization (feelings of unreality) or depersonalization (being detached from oneself)
- Fear of losing control or "going crazy"
- Fear of dying
- At least one of the attacks has been followed by 1 month (or more) of:
- Persistent concern or worry about additional panic attacks or their consequences
- Significant maladaptive change in behavior related to the attacks
Mental Status Examination (MSE)
- Appearance and behavior: may present as well-kempt or disheveled
- Motor activity: may have psychomotor agitation
- Speech: may be fast or pressured; if in a panic attack, may have difficulty speaking (stammering, vocal tremor)
- Affect and mood: may describe mood as anxious, afraid, tense, exhausted, frustrated, "on edge", or irritable; or depressed
- Thought process: may include ruminations
- Thought content: extreme fear, sense of impending doom (in an attack); anticipatory anxiety about having another attack (between attacks)
- Perception: often a negative view of themselves and of the world
- Sensorium and cognition: may have difficulty concentrating, mind blank, or confused during an attack
- Insight: often aware fears are out of proportion to the actual threat
- Judgement: tend to use avoidance behaviors
PHQ-PD Module
- Questions to assess panic disorder:
- Have you had an anxiety attack with sudden fear or panic in the last 4 weeks?
- Has this ever happened before?
- Do some of these attacks come suddenly, out of the blue, in situations where you do not expect nervousness?
- Do these attacks bother you a lot or are you worried about having another attack?
- Have you had these symptoms during your last bad anxiety episode?
Autonomic Nervous System (ANS) Questionnaire
- Questions to assess panic disorder:
- Have you ever had a spell or an attack when all of a sudden you felt frightened, anxious, or very uneasy?
- Have you ever had a spell or attack when for no reason your heart suddenly began to race, you felt faint, or you couldn't catch your breath?
Panic Disorder Screening Questionnaires Scoring
- PHQ-PD (1- or 5-item) and ANS can be used to screen for panic disorder
- Severity often assessed using a different questionnaire (e.g. PDSS-SR)
- Likelihood ratios to identify panic disorder (PD) using PHQ-PD 1, PHQ-PD 5, and ANS questionnaires
Adjustment Disorder
- Definition: a maladaptive emotional and/or behavioral response to an identifiable psychosocial stressor
- Prevalence: 1-2% (general), 5-20% (outpatient mental health visit), 27% (recently unemployed), 18% (bereaved)
- Risk factors: significant life event(s)
- Diagnosis: by clinical interview (according to DSM-5 criteria), no validated assessment tools
- Timeline: onset shortly after stressor, typically resolves within 6 months after stressor has stopped (or becomes classified as 'chronic adjustment disorder')
- Character: with anxiety, depressed mood (may include suicide attempt), mixed, with misconduct, or unspecified
- Management: patient education, referral to psychotherapy, psychiatry
- Prognosis: 71% recover within 5 years, 76% comorbidity with substance abuse
Other Disorders
- Stress: a physical or mental response to an external stressor, considered a risk factor, an exacerbating factor, and a treatment target – not a diagnosis itself
- Depressed mood: a depressive syndrome that causes distress and psychosocial impairment for at least 2 weeks, but is not considered clinical depression (aka. major depression)
- Dysthymic disorder: depressed mood for most of the day, more days than not, for at least 2 years
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Description
Identify the causes of low back pain, including lumbar radiculopathy, spinal stenosis, and visceral disease. Understand the differences between serious and emergent conditions.