Types of Chemotherapy Drugs
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Questions and Answers

what are the 6 types of chemotherapy drugs

topoisomerase enzymes, mitotic spindle agents, antimetabolites and cytotoxic drugs, alkylating agents and hormonal agents

what is the action of alkylating agents

structural damage to mature DNA

Wat is the action of hormonal agents

blocks proliferation of hormone responsive cells

what do antimetabolites do

<p>block the synthesis of nucleic acid precursers reducing synthesis of purine and pyrimidines</p> Signup and view all the answers

what do topoisomerase enzymes do

<p>participate in the winding and unwinding of DNA</p> Signup and view all the answers

what do mitotic spindle agents do

<p>bind to microtubular protiens inhibiting microtubule assembly interrupting mitosis of cell division</p> Signup and view all the answers

what are the 4 levels of drug response

<ol> <li>progressive disease, stable disease, partial response and complete response</li> </ol> Signup and view all the answers

what is partial response?

<p>atleast 30% decrease of lesions</p> Signup and view all the answers

what is progressive disease

<p>atleast 20% increase in lesions</p> Signup and view all the answers

what are the types of chemotherapy (4)

<p>neoadjuvant, adjuvant, salvage and palliative</p> Signup and view all the answers

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