Types of AD Biomarkers
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Questions and Answers

What method is used to analyze cerebral spinal fluid (CSF) biomarkers?

  • Blood sample analysis
  • Computed Tomography (CT) scan
  • Magnetic Resonance Imaging (MRI)
  • Lumber puncture (correct)
  • What type of scan is used to examine amyloid and tau biomarkers?

  • Ultrasound
  • Electroencephalogram (EEG)
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET) scan (correct)
  • Which component is essential in the blood analysis described for dementia biomarkers?

  • Antibodies that induce blood clotting
  • Paramagnetic particles coupled with antibodies (correct)
  • Nucleic acids for genetic mapping
  • Synthetic proteins for enhancing fluorescence
  • What is the ultimate goal of the blood biomarker analysis for dementia?

    <p>To form an immunocomplex with detection antibodies</p> Signup and view all the answers

    Why are fluorescent detection antibodies used in the blood analysis process?

    <p>To generate a fluorescent product for detection</p> Signup and view all the answers

    Which of the following statements about blood biomarkers in dementia is inaccurate?

    <p>Blood samples for dementia analysis do not require any additional substances.</p> Signup and view all the answers

    What is the main technique that supports the identification of plaques and tangles in the brain through biomarkers?

    <p>Lumber puncture analysis</p> Signup and view all the answers

    Which method is utilized to analyze molecular biomarkers such as amyloid and tau?

    <p>PET scan</p> Signup and view all the answers

    Which of the following processes is involved in creating an immunocomplex during the blood biomarker analysis?

    <p>Adding paramagnetic particles coupled with antibodies to the blood sample</p> Signup and view all the answers

    What primary advantage do biosensors used in blood biomarker detection offer?

    <p>Enhanced sensitivity to detect lower concentrations of biomarkers</p> Signup and view all the answers

    What is the primary role of paramagnetic particles in blood biomarker analysis for dementia?

    <p>To bind to specific targets in the blood.</p> Signup and view all the answers

    Which step follows the addition of paramagnetic particles in the blood biomarker analysis process?

    <p>An immunocomplex is formed.</p> Signup and view all the answers

    Which of the following is an advantage of using fluorescent detection antibodies in blood biomarker analysis?

    <p>They can enhance visibility of biomarker presence.</p> Signup and view all the answers

    How are tangles and plaques identified in the context of dementia biomarkers?

    <p>Via analysis of molecular biomarkers in CSF.</p> Signup and view all the answers

    What is the main analytical technique utilized for identifying amyloid and tau biomarkers?

    <p>Positron emission tomography (PET) scan.</p> Signup and view all the answers

    Study Notes

    Types of AD Biomarkers

    • Cerebral Spinal Fluid (CSF): Analyzed via lumbar puncture, identifying brain tangles and plaques using CSF.

    • Amyloid and Tau: Analysed via PET scan. Includes molecular biomarkers.

    • Blood: Uses paramagnetic particles coupled with antibodies targeted to specific markers in the blood sample. Detection antibodies are added to the blood sample to produce a fluorescent product. The objective is to form an immunocomplex of the bead, bound protein, and detection antibody.

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    Description

    This quiz explores the various types of biomarkers used for Alzheimer's Disease (AD) diagnosis and monitoring. It covers methods such as analyzing Cerebral Spinal Fluid (CSF), PET scans for amyloid and tau proteins, and blood tests utilizing immunocomplex formation. Test your understanding of these critical diagnostic techniques.

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