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Questions and Answers

What is the recommended pharmacological approach for people with mild to moderate Alzheimer's disease?

Memantine as a first-line treatment

No pharmacological treatment is recommended

Donepezil, galantamine, or rivastigmine as single agents (correct)

Donepezil, galantamine, or rivastigmine in combination with memantine

When should memantine be considered for people with Alzheimer's disease?

If they have mild disease and are not taking an AChE inhibitor

If they have severe disease and are taking an AChE inhibitor

If they have moderate disease and are intolerant or have a contraindication to an AChE inhibitor (correct)

If they have any severity of disease and are not taking an AChE inhibitor

What is the recommended approach for people with dementia with Lewy bodies who are intolerant to AChE inhibitors?

Do not consider any pharmacological treatment

Consider memantine as a first-line treatment

Consider galantamine only if donepezil and rivastigmine are not tolerated (correct)

Consider galantamine as a first-line treatment

What is the recommended approach for people with vascular dementia?

Offer AChE inhibitors or memantine only if they have suspected comorbid Alzheimer's disease, Parkinson's disease dementia or dementia with Lewy bodies Signup and view all the answers

What is the recommended approach for people with Alzheimer's disease who are already taking an AChE inhibitor and have severe disease?

Consider adding memantine to their treatment Signup and view all the answers

What is the recommended pharmacological approach for people with mild to moderate dementia with Lewy bodies?

Offer donepezil or rivastigmine as a first-line treatment Signup and view all the answers

What is the primary focus of the initial and ongoing management of non-cognitive symptoms in people living with dementia?

Psychosocial and environmental interventions Signup and view all the answers

In what circumstances can antipsychotics be offered to people living with dementia?

When there is a risk of harm to themselves or others, or when experiencing agitation, hallucinations, or delusions causing severe distress Signup and view all the answers

What should be considered when discussing antipsychotics with the person and their family members or carers?

Both the benefits and harms of antipsychotics Signup and view all the answers

What should be avoided in people living with dementia, due to the increased risk of stroke and death?

Antipsychotics for mild to moderate non-cognitive symptoms Signup and view all the answers

What should be stopped if no clear ongoing benefit is seen, and after discussion with the person and their family members or carers?

Antipsychotics Signup and view all the answers

What is not recommended for managing agitation or aggression in people living with dementia, unless indicated for another condition?

Valproate Signup and view all the answers