12 Questions
What is the recommended pharmacological approach for people with mild to moderate Alzheimer's disease?
Donepezil, galantamine, or rivastigmine as single agents
When should memantine be considered for people with Alzheimer's disease?
If they have moderate disease and are intolerant or have a contraindication to an AChE inhibitor
What is the recommended approach for people with dementia with Lewy bodies who are intolerant to AChE inhibitors?
Consider galantamine only if donepezil and rivastigmine are not tolerated
What is the recommended approach for people with vascular dementia?
Offer AChE inhibitors or memantine only if they have suspected comorbid Alzheimer's disease, Parkinson's disease dementia or dementia with Lewy bodies
What is the recommended approach for people with Alzheimer's disease who are already taking an AChE inhibitor and have severe disease?
Consider adding memantine to their treatment
What is the recommended pharmacological approach for people with mild to moderate dementia with Lewy bodies?
Offer donepezil or rivastigmine as a first-line treatment
What is the primary focus of the initial and ongoing management of non-cognitive symptoms in people living with dementia?
Psychosocial and environmental interventions
In what circumstances can antipsychotics be offered to people living with dementia?
When there is a risk of harm to themselves or others, or when experiencing agitation, hallucinations, or delusions causing severe distress
What should be considered when discussing antipsychotics with the person and their family members or carers?
Both the benefits and harms of antipsychotics
What should be avoided in people living with dementia, due to the increased risk of stroke and death?
Antipsychotics for mild to moderate non-cognitive symptoms
What should be stopped if no clear ongoing benefit is seen, and after discussion with the person and their family members or carers?
Antipsychotics
What is not recommended for managing agitation or aggression in people living with dementia, unless indicated for another condition?
Valproate
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