Type II Hypersensitivity Reaction Quiz
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Questions and Answers

What is the clinical manifestation of Myasthenia Gravis?

  • Diminished vitamin B12 absorption
  • Destruction of red blood cells
  • Hyperthyroidism
  • Weakness of the skeletal muscles (correct)

Which condition is characterized by the overactivity of the thyroid gland?

  • Autoimmune hemolytic anemia
  • Grave’s Disease (correct)
  • Myasthenia Gravis
  • Pernicious Anemia

What type of hypersensitivity reaction involves antibodies attacking soluble antigens circulating in the plasma?

  • Type III Immune Complex-Mediated (correct)
  • Type II Clinical Examples
  • Type III Clinical Examples
  • Type II Antibody-Mediated Cytotoxic Type

Which condition is associated with a malfunction of the immune system producing autoantibodies that attack red blood cells?

<p>Autoimmune hemolytic anemia (D)</p> Signup and view all the answers

What is the characteristic feature of Type III hypersensitivity reactions?

<p>Complement activation and accumulation of PMN's (C)</p> Signup and view all the answers

Which antigen type is mentioned as an example of endogenous antigens in the text?

<p><em>DNA</em> (D)</p> Signup and view all the answers

What type of hypersensitivity reaction involves antibodies that react with antigens on cell surfaces or in the extracellular matrix?

<p>Type II (B)</p> Signup and view all the answers

Which immunoglobulins are involved in Type II hypersensitivity reactions?

<p>IgG and IgM (D)</p> Signup and view all the answers

What is the main mechanism of Type II hypersensitivity involving the formation of membrane attack complex (MAC)?

<p>Antibody and Complement-Mediated Destruction (D)</p> Signup and view all the answers

Which condition is associated with Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Type II hypersensitivity?

<p>Transplant rejection (D)</p> Signup and view all the answers

In Type II hypersensitivity reactions, what triggers either phagocytosis of target cells or lysis by complement activation?

<p>IgM plus complement (D)</p> Signup and view all the answers

What is the role of IgG in the Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) mechanism of Type II hypersensitivity?

<p>Opsonin for phagocytosis (C)</p> Signup and view all the answers

What type of hypersensitivity reaction is associated with immune system attacking self-antigens?

<p>Type IV (A)</p> Signup and view all the answers

Which autoimmune disease is more common in females and affects multiple organs or systems?

<p>Rheumatoid arthritis (D)</p> Signup and view all the answers

What environmental factors can contribute to the development of autoimmune diseases?

<p>Smoking (C)</p> Signup and view all the answers

In autoimmune diseases, what does the immune system mistakenly attack?

<p>Healthy cells and tissues (A)</p> Signup and view all the answers

Which type of immunity disorder involves the body attacking its own tissues?

<p>Autoimmune diseases (D)</p> Signup and view all the answers

What is the Mantoux test used for in relation to tuberculosis?

<p>Diagnosing active tuberculosis (B)</p> Signup and view all the answers

What is the role of antibodies in rheumatoid arthritis?

<p>They attach to joint linings. (D)</p> Signup and view all the answers

Which autoimmune disease commonly affects joints, lungs, blood cells, nerves, and kidneys?

<p>Systemic lupus erythematosus (lupus) (D)</p> Signup and view all the answers

What is the main effect of autoimmune diseases on the body?

<p>Attacks on body tissues by the immune system (D)</p> Signup and view all the answers

How does inflammatory bowel disease (IBD) primarily manifest in individuals?

<p>Episodes of diarrhea and rectal bleeding (D)</p> Signup and view all the answers

Which genes are associated with susceptibility to autoimmune diseases?

<p>IRF5 and PTPN22 (D)</p> Signup and view all the answers

What type of medications are used to treat multiple sclerosis (MS)?

<p>Immune-suppressing medicines (D)</p> Signup and view all the answers

What genes are associated with autoimmune diseases like Type 1 diabetes mellitus and Guillain-Barre syndrome?

<p>HLA-DRB1 (B)</p> Signup and view all the answers

Which autoimmune disease involves the immune system attacking nerves controlling muscles in the legs?

<p>Chronic inflammatory demyelinating polyneuropathy (A)</p> Signup and view all the answers

What environmental factor is mentioned in relation to autoimmune diseases?

<p>Smoking (A)</p> Signup and view all the answers

In Psoriasis, what does the immune system activity stimulate to reproduce rapidly?

<p>Skin cells (C)</p> Signup and view all the answers

What autoimmune disease results in excess amounts of thyroid hormone being released into the blood?

<p>Graves' disease (B)</p> Signup and view all the answers

What autoimmune disease involves the immune system attacking insulin-producing cells in the pancreas?

<p>Type 1 diabetes mellitus (A)</p> Signup and view all the answers

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