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Questions and Answers
Which type of hypersensitivity reaction involves antibodies of the IgG and IgM classes?
Which type of hypersensitivity reaction involves antibodies of the IgG and IgM classes?
- Type II hypersensitivity (correct)
- Type I hypersensitivity
- Type IV hypersensitivity
- Type III hypersensitivity
What is the mechanism of type III hypersensitivity reaction?
What is the mechanism of type III hypersensitivity reaction?
- Antigen directly causes lysis of target cells
- T cells directly attack self-antigens
- Antibodies combine with the antigen, leading to immune complex formation (correct)
- Antibodies attach to mast cells and basophils, leading to degranulation
Which condition is an example of type II hypersensitivity?
Which condition is an example of type II hypersensitivity?
- Systemic lupus erythematosus
- Incompatible blood transfusion (correct)
- Rheumatoid arthritis
- Type 1 diabetes mellitus
What is an example of a condition caused by type III hypersensitivity reaction?
What is an example of a condition caused by type III hypersensitivity reaction?
Which type of hypersensitivity reaction involves complement activation?
Which type of hypersensitivity reaction involves complement activation?
What is an example of an immune complex reaction caused by type III hypersensitivity?
What is an example of an immune complex reaction caused by type III hypersensitivity?
Which type of hypersensitivity reaction involves antibodies combining with the antigen producing immune complexes trapped within vascular basement membranes?
Which type of hypersensitivity reaction involves antibodies combining with the antigen producing immune complexes trapped within vascular basement membranes?
What type of reaction involves repeated subcutaneous injection of antigens producing local vasculitis, necrosis, and edema?
What type of reaction involves repeated subcutaneous injection of antigens producing local vasculitis, necrosis, and edema?
What happens in type II hypersensitivity when the antigen is a component of a cell membrane?
What happens in type II hypersensitivity when the antigen is a component of a cell membrane?
What is an example of a condition caused by type II hypersensitivity involving autoimmune destruction of red blood cells?
What is an example of a condition caused by type II hypersensitivity involving autoimmune destruction of red blood cells?
Which type of hypersensitivity is characterized by the antigen stimulating T lymphocytes and causing cell-mediated immunity?
Which type of hypersensitivity is characterized by the antigen stimulating T lymphocytes and causing cell-mediated immunity?
What is the hallmark of collagen diseases (connective tissue diseases)?
What is the hallmark of collagen diseases (connective tissue diseases)?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
Which condition results from altered tissue antigenicity due to the actions of microorganisms or drugs?
Which condition results from altered tissue antigenicity due to the actions of microorganisms or drugs?
What is the common feature of endocrine diseases such as Hashimoto's thyroiditis and autoimmune hemolytic anemia?
What is the common feature of endocrine diseases such as Hashimoto's thyroiditis and autoimmune hemolytic anemia?
What is an example of a type IV hypersensitivity reaction?
What is an example of a type IV hypersensitivity reaction?
What is the mechanism of immune complex formation in autoimmune diseases like SLE?
What is the mechanism of immune complex formation in autoimmune diseases like SLE?
"Immunodeficiency" involves a deficient response that may affect:
"Immunodeficiency" involves a deficient response that may affect:
"Loss of tolerance" in autoimmunity refers to:
"Loss of tolerance" in autoimmunity refers to:
"Cross reactions" can occur between:
"Cross reactions" can occur between:
Which type of hypersensitivity reaction requires complement activation and leads to lysis of target cells?
Which type of hypersensitivity reaction requires complement activation and leads to lysis of target cells?
What is an example of a condition caused by Type III hypersensitivity reaction?
What is an example of a condition caused by Type III hypersensitivity reaction?
What is the mechanism of immune complex formation in Type III hypersensitivity?
What is the mechanism of immune complex formation in Type III hypersensitivity?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
What is the hallmark of collagen diseases?
What is the hallmark of collagen diseases?
In which autoimmune disease is systemic fibrosis known to affect the skin, GIT, lung, myocardium & kidneys?
In which autoimmune disease is systemic fibrosis known to affect the skin, GIT, lung, myocardium & kidneys?
What mechanism may lead to altered tissue antigenicity in autoimmune diseases?
What mechanism may lead to altered tissue antigenicity in autoimmune diseases?
Which condition results from loss of tolerance where normal tissue components are considered antigenic, leading to tissue destruction & disease development?
Which condition results from loss of tolerance where normal tissue components are considered antigenic, leading to tissue destruction & disease development?
What type of hypersensitivity reaction involves cell-mediated graft rejection and caseous necrosis in tuberculosis?
What type of hypersensitivity reaction involves cell-mediated graft rejection and caseous necrosis in tuberculosis?
What is the mechanism of immune complex formation in Type III hypersensitivity?
What is the mechanism of immune complex formation in Type III hypersensitivity?
Which autoimmune disease is characterized by systemic fibrosis affecting skin, GIT, lung, myocardium & kidneys?
Which autoimmune disease is characterized by systemic fibrosis affecting skin, GIT, lung, myocardium & kidneys?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
In which autoimmune disease is Hashimoto's thyroiditis an example?
In which autoimmune disease is Hashimoto's thyroiditis an example?
What type of reaction involves repeated subcutaneous injection of antigens producing local vasculitis, necrosis, and edema?
What type of reaction involves repeated subcutaneous injection of antigens producing local vasculitis, necrosis, and edema?
What type of hypersensitivity reaction involves the antibodies (IgG and IgM) combining with the antigen producing immune complexes trapped within vascular basement membranes?
What type of hypersensitivity reaction involves the antibodies (IgG and IgM) combining with the antigen producing immune complexes trapped within vascular basement membranes?
Which condition results from loss of tolerance where normal tissue components are considered antigenic, leading to tissue destruction and disease development?
Which condition results from loss of tolerance where normal tissue components are considered antigenic, leading to tissue destruction and disease development?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
What happens in Type II hypersensitivity when the antigen is a component of a cell membrane?
What is an example of a condition caused by Type III hypersensitivity reaction?
What is an example of a condition caused by Type III hypersensitivity reaction?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
Which autoimmune disease is characterized by injury of collagen within and around vessels?
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