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Type 2 Diabetes Clinical Study

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Questions and Answers

What is the primary goal of this study?

To assess the proportion of participants achieving HbA1c less than 7.0%

To compare the efficacy, safety, and tolerability of combination therapy of dapagliflozin plus linagliptin versus dapagliflozin plus vildagliptin as add-on therapy (correct)

To evaluate the effect of metformin on body weight

To compare the efficacy of linagliptin and vildagliptin as monotherapy

How many participants were randomly assigned in this study?

236 participants (correct)

100 participants

200 participants

300 participants

What is the primary outcome measured in this study?

Mean change in postprandial blood glucose (PPBG)

Mean change in fasting blood glucose (FBG)

Mean change in hemoglobin A1c (HbA1c) from baseline to the end of week 16 (correct)

Proportion of participants achieving HbA1c less than 7.0%

What is the duration of this study?

18 weeks Signup and view all the answers

What is the dose of dapagliflozin used in this study?

10 mg Signup and view all the answers

What is the key secondary endpoint measured in this study?

All of the above Signup and view all the answers

What is the difference in mean reduction of HbA1c between the dapagliflozin/linagliptin and dapagliflozin/vildagliptin groups?

-1.59% vs.-1.25% Signup and view all the answers

What is the dose of vildagliptin used in this study?

100 mg Signup and view all the answers

What type of diabetes patients are enrolled in this study?

Type 2 diabetes mellitus (T2DM) patients Signup and view all the answers

What is the treatment that participants received in addition to metformin?

Either a or b Signup and view all the answers