Type 1 Diabetes: Hereditary Lack of Insulin

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Which of the following is the most common diagnostic tool used for diabetes?

Fasting blood glucose (FBG) test

What is the main drawback of the oral glucose tolerance test (OGTT) mentioned in the text?

It gives many false-positive results due to stress-induced epinephrine release.

What is the reference range for HbA1C in normal individuals?

5.1-6.3%

Which of the following is a diagnostic criterion for diabetes according to the text?

<p>All of the above</p> Signup and view all the answers

Which of the following is a common complication of type 1 diabetes?

<p>All of the above</p> Signup and view all the answers

What causes Type 1 diabetes?

<p>Genetic predisposition and autoimmune destruction of insulin-producing cells</p> Signup and view all the answers

Why is the measurement of HbA1C considered a good indicator of long-term glucose control?

<p>HbA1C levels remain stable for the lifespan of red blood cells, which is around 3 months.</p> Signup and view all the answers

What percentage of people are affected by Type 1 diabetes?

<p>5%</p> Signup and view all the answers

What is insulitis?

<p>Infiltration of activated T lymphocytes in pancreatic cells</p> Signup and view all the answers

At what point do symptoms of Type 1 diabetes appear?

<p>When 80-90% of beta cells are destroyed</p> Signup and view all the answers

What triggers the destruction of beta cells in Type 1 diabetes?

<p>Genetic determinant and environmental stimulus like viral infection</p> Signup and view all the answers

Why is insulin therapy required in Type 1 diabetes?

<p>To restore metabolic control and prevent ketoacidosis</p> Signup and view all the answers

Which of the following is a symptom of type 1 diabetes?

<p>Blurred vision</p> Signup and view all the answers

Which enzyme would be more active in diabetic patients?

<p>Hormone-sensitive lipase</p> Signup and view all the answers

Which of the following is NOT a consequence of insulin deficiency in lipid metabolism?

<p>Increased triglyceride breakdown</p> Signup and view all the answers

Which of the following best describes type 1 diabetes?

<p>An autoimmune disease that attacks the beta cells of the pancreas</p> Signup and view all the answers

Which of the following can cause hypoglycemia in type 1 diabetes patients?

<p>All of the above</p> Signup and view all the answers

What should type 1 diabetes patients do to prevent hypoglycemia during exercise?

<p>Check blood glucose levels before and after intensive exercise</p> Signup and view all the answers

What is the primary treatment for ketoacidosis in type 1 diabetes?

<p>Replacing fluid and electrolytes, followed by low-dose insulin</p> Signup and view all the answers

Compared to fasting, which of the following is a key metabolic difference in type 1 diabetes?

<p>Absence of insulin in the blood</p> Signup and view all the answers

Which of the following statements about ketosis is true in type 1 diabetes compared to fasting?

<p>Ketosis is more severe in type 1 diabetes</p> Signup and view all the answers

What is the primary reason for hypertriacylglycerolemia in type 1 diabetes?

<p>Increased hepatic synthesis of triacylglycerols due to high free fatty acid levels</p> Signup and view all the answers

Which of the following statements is true about blood glucose levels in type 1 diabetes compared to fasting?

<p>Blood glucose levels are higher in type 1 diabetes</p> Signup and view all the answers

What is the primary method of managing Type 1 diabetes?

<p>Insulin replacement through lifelong insulin injections or insulin pump</p> Signup and view all the answers

Why is close management and daily care essential for individuals with type 1 diabetes?

<p>Because it is a life-threatening condition</p> Signup and view all the answers

What could happen if blood glucose levels are too high in Type 1 diabetes?

<p>Hyperglycemia or ketoacidosis</p> Signup and view all the answers

Which of the following is NOT a component of managing Type 1 diabetes?

<p>Taking oral diabetes medications</p> Signup and view all the answers

What is the most common complication of intensive insulin therapy in Type 1 diabetes?

<p>Hypoglycemia</p> Signup and view all the answers

What compensatory mechanism is impaired in patients with Type 1 diabetes?

<p>Glucagon secretion</p> Signup and view all the answers

Which of the following statements about managing Type 1 diabetes is TRUE?

<p>Keeping blood glucose levels at the optimum range requires balancing diet, exercise, and medication</p> Signup and view all the answers

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