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Tumor Markers and Physiological Antigens Quiz

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Tumor Markers and Physiological Antigens Quiz

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Questions and Answers

What is the immune stimulatory role of CA 15-3?

It is involved in immune system regulation in patients with colorectal cancer

It has no immune stimulatory role

It inhibits the immune response in patients with metastatic breast cancer

It activates the immune response in patients with early localized breast cancer (correct)

What is the primary role of CA 19-9?

It is a glycolipid involved in pancreatic cancer staging (correct)

It is a determinant of the Lewis a blood group

It is a marker for lung and ovarian carcinomas

It stimulates immune response in patients with hepatobiliary cancer

What is the main function of CA 125?

It is specific for ovarian and endometrial carcinomas

It is useful in detecting residual disease in cancer patients following initial therapy (correct)

It elevates in patients with lung and breast cancer

It is a marker for colorectal and gastrointestinal (GI) cancers

What does Thyroglobulin (Tg) primarily indicate?

It is completely used within the thyroid gland Signup and view all the answers

What is the relationship between the unbound portion of PSA (fPSA) and the probability of prostate cancer?

The unbound portion of PSA is inversely related to the probability of prostate cancer Signup and view all the answers

Which of the following markers are routinely assessed in relation to tissue and organ specific antigens (CA)?

CA 15-3, CA19-9 & CA 125 Signup and view all the answers

What is the significance of monitoring CA markers such as CA 15-3, CA19-9 & CA 125?

They help differentiate between prostate cancer and benign prostatic hyperplasia Signup and view all the answers

What is the relationship between PSA density and prostatic volume?

PSA density increases as prostatic volume increases Signup and view all the answers

Which tissue or organ specific antigen is associated with tumors of the head, lung, and esophagus?

Squamous cells carcinoma antigen (SCC) Signup and view all the answers

Which onco-fetal antigen is structurally similar to albumin and used for the diagnosis and monitoring of hepatocellular carcinoma (HCC)?

AFP (alpha-fetoprotein) Signup and view all the answers

Which antigen is physiologically present in healthy tissue or organ, but released outside only in minimal amounts during pathological states such as tumors, inflammation, and injury?

Thyroglobulin (TG) Signup and view all the answers

Which non-specific antigen is an enzyme produced by tumors as a reaction to the presence of the tumor, and is used as a marker for various malignancies?

Ferritin Signup and view all the answers