Tumor Markers and Physiological Antigens Quiz

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12 Questions

What is the immune stimulatory role of CA 15-3?

It activates the immune response in patients with early localized breast cancer

What is the primary role of CA 19-9?

It is a glycolipid involved in pancreatic cancer staging

What is the main function of CA 125?

It is useful in detecting residual disease in cancer patients following initial therapy

What does Thyroglobulin (Tg) primarily indicate?

It is completely used within the thyroid gland

What is the relationship between the unbound portion of PSA (fPSA) and the probability of prostate cancer?

The unbound portion of PSA is inversely related to the probability of prostate cancer

Which of the following markers are routinely assessed in relation to tissue and organ specific antigens (CA)?

CA 15-3, CA19-9 & CA 125

What is the significance of monitoring CA markers such as CA 15-3, CA19-9 & CA 125?

They help differentiate between prostate cancer and benign prostatic hyperplasia

What is the relationship between PSA density and prostatic volume?

PSA density increases as prostatic volume increases

Which tissue or organ specific antigen is associated with tumors of the head, lung, and esophagus?

Squamous cells carcinoma antigen (SCC)

Which onco-fetal antigen is structurally similar to albumin and used for the diagnosis and monitoring of hepatocellular carcinoma (HCC)?

AFP (alpha-fetoprotein)

Which antigen is physiologically present in healthy tissue or organ, but released outside only in minimal amounts during pathological states such as tumors, inflammation, and injury?

Thyroglobulin (TG)

Which non-specific antigen is an enzyme produced by tumors as a reaction to the presence of the tumor, and is used as a marker for various malignancies?

Ferritin

Test your knowledge of tumor markers and physiological antigens with this quiz. Explore the roles of human chorionic gonadotrophin (hCG), placental alkaline phosphatase (PLAP), prostatic specific antigen (PSA), and other tissue-specific antigens in healthy and pathological states.

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