6 Questions
Which marker is used primarily for follow-up and not early diagnosis of ovarian carcinoma?
CA-125
Markers of host response to tumor are characterized by which two features?
Low sensitivity and low specificity
Steroid receptors bind which of the following hormones in malignant breast tissues?
Estrogen and progesterone
Which type of tumor marker is used exclusively through tumor tissue biopsy?
Cellular markers related to prognosis
Uric acid is an example of which type of biochemical marker?
Product of metabolism
The presence of steroid receptors in malignant breast tissues is an indicator of what?
Good response to endocrine therapy
Study Notes
Tumor Markers
-
Cell Surface Glycoproteins and Mucins:
- Used for follow-up of certain tumors, not for early diagnosis
- Example: CA-125 is used in ovarian carcinoma
Markers of Host Response to Tumor:
- Characterized by low sensitivity and specificity
- May be the only biochemical markers for follow-up in some tumors
- Examples:
- Acute phase reactants, such as α1 acid glycoprotein and c-reactive protein
- Products of metabolism, such as uric acid
Cellular Markers Related to Prognosis:
- Detected only on tumor tissue biopsy
- Related to prognosis of tumors
Steroid Receptors:
- Cytoplasmic receptors that bind estrogen and progesterone
- Present in normal and malignant breast tissues
- Higher percentage found in postmenopausal women
- Presence in malignant breast tissues indicates good response to endocrine therapy
Genes and Nucleic Acid:
- Patterns of genes or alterations in nucleic acid structures used for tumor detection
- Specifically, looks at changes in genes or nucleic acid structures that occur in certain tumors
This quiz covers tumor markers, including cell surface glycoproteins, mucins, and markers of host response to tumor. Learn about their uses and limitations in cancer diagnosis and follow-up.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
