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Questions and Answers
Which of the following is a property of a good tumor marker?
Which type of molecule can be classified as a tumor marker?
What is the role of genetic changes in tumor markers?
In relation to tumor markers, what is the significance of a long half life?
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What should the plasma level of a good tumor marker be in relation to healthy subjects and benign conditions?
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Study Notes
Tumor Markers
Properties of Good Tumor Markers
- A good tumor marker should have high sensitivity and specificity to detect cancer
- A good tumor marker should have a high positive predictive value to accurately diagnose cancer and avoid false positives
Types of Tumor Markers
- Proteins, such as enzymes, hormones, and receptors, can be classified as tumor markers
- Genetic material, such as DNA and RNA, can also be classified as tumor markers
Genetic Changes in Tumor Markers
- Genetic changes, such as mutations and overexpression, can contribute to the development of tumor markers
- Genetic changes can cause altered gene expression, leading to changes in protein production or function
Significance of Half-Life
- A long half-life allows for consistent and reliable detection of tumor markers in the blood
- A long half-life enables monitoring of tumor marker levels over time to track treatment response or disease progression
Ideal Plasma Levels
- The plasma level of a good tumor marker should be low or undetectable in healthy subjects and benign conditions
- The plasma level of a good tumor marker should be significantly elevated in cancer patients
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Description
Test your knowledge about tumor markers, the molecules associated with abnormal production in cancer and measured in plasma. Learn about the properties of a good tumor marker and its relevance in cancer diagnosis.
