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Questions and Answers
Which of the following is a property of a good tumor marker?
Which of the following is a property of a good tumor marker?
- It should have the same immunological properties when synthesized in other tissues
- Its plasma level should be higher in healthy subjects
- It should be present in healthy tissues
- Its plasma level should be in proportion to the size of the tumor (correct)
Which type of molecule can be classified as a tumor marker?
Which type of molecule can be classified as a tumor marker?
- Nucleotides
- Carbohydrates (correct)
- Lipids
- Vitamins
What is the role of genetic changes in tumor markers?
What is the role of genetic changes in tumor markers?
- They affect the half life of a tumor
- They cause benign conditions
- They have no impact on tumor markers
- They lead to mutations in some oncogenes and tumor suppressor genes (correct)
In relation to tumor markers, what is the significance of a long half life?
In relation to tumor markers, what is the significance of a long half life?
What should the plasma level of a good tumor marker be in relation to healthy subjects and benign conditions?
What should the plasma level of a good tumor marker be in relation to healthy subjects and benign conditions?
Flashcards
Good tumor marker plasma level
Good tumor marker plasma level
The plasma level of a good tumor marker should proportionally reflect the tumor size.
Tumor marker molecule type
Tumor marker molecule type
Carbohydrates can act as tumor markers.
Genetic changes & tumor markers
Genetic changes & tumor markers
Genetic changes cause mutations in oncogenes and tumor suppressor genes, affecting tumor markers.
Tumor marker half-life
Tumor marker half-life
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Tumor marker & healthy levels
Tumor marker & healthy levels
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Study Notes
Tumor Markers
Properties of Good Tumor Markers
- A good tumor marker should have high sensitivity and specificity to detect cancer
- A good tumor marker should have a high positive predictive value to accurately diagnose cancer and avoid false positives
Types of Tumor Markers
- Proteins, such as enzymes, hormones, and receptors, can be classified as tumor markers
- Genetic material, such as DNA and RNA, can also be classified as tumor markers
Genetic Changes in Tumor Markers
- Genetic changes, such as mutations and overexpression, can contribute to the development of tumor markers
- Genetic changes can cause altered gene expression, leading to changes in protein production or function
Significance of Half-Life
- A long half-life allows for consistent and reliable detection of tumor markers in the blood
- A long half-life enables monitoring of tumor marker levels over time to track treatment response or disease progression
Ideal Plasma Levels
- The plasma level of a good tumor marker should be low or undetectable in healthy subjects and benign conditions
- The plasma level of a good tumor marker should be significantly elevated in cancer patients
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