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Tumor Invasion and Spread
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Tumor Invasion and Spread

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Questions and Answers

What is the characteristic route of metastasis for carcinomas?

  • Lymphatic spread (correct)
  • Seeding of body cavities
  • Direct invasion of adjacent tissues
  • Hematogenous spread

    • What is the initial site of spread for lymphatic metastasis?

  • Bone marrow
  • Liver
  • Lungs
  • Regional draining lymph nodes (correct)

    • Which molecule downregulation leads to dissociation of attached epithelial tumor cells?

  • Collagenase
  • Fibronectin
  • E-cadherin (correct)
  • Laminin

    • What is the characteristic route of metastasis for sarcomas and some carcinomas?

    <p>Hematogenous spread</p> Signup and view all the answers

    Which type of carcinoma often involves the peritoneum?

    <p>Ovarian carcinoma</p> Signup and view all the answers

    What is a key characteristic of malignant tumors?

    <p>Rapid growth and infiltration</p> Signup and view all the answers

    What is a characteristic feature of benign tumors?

    <p>Low nuclear to cytoplasmic ratio</p> Signup and view all the answers

    What is the hallmark of malignancy?

    <p>Metastatic potential</p> Signup and view all the answers

    What is the purpose of immunohistochemistry in tumor characterization?

    <p>To characterize tumors that are difficult to classify on histology</p> Signup and view all the answers

    What is the importance of grading in cancer assessment?

    <p>Determining prognosis based on differentiation</p> Signup and view all the answers

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