Tumor Invasion and Spread

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Questions and Answers

What is the characteristic route of metastasis for carcinomas?

  • Lymphatic spread (correct)
  • Seeding of body cavities
  • Direct invasion of adjacent tissues
  • Hematogenous spread

What is the initial site of spread for lymphatic metastasis?

  • Bone marrow
  • Liver
  • Lungs
  • Regional draining lymph nodes (correct)

Which molecule downregulation leads to dissociation of attached epithelial tumor cells?

  • Collagenase
  • Fibronectin
  • E-cadherin (correct)
  • Laminin

What is the characteristic route of metastasis for sarcomas and some carcinomas?

<p>Hematogenous spread (B)</p> Signup and view all the answers

Which type of carcinoma often involves the peritoneum?

<p>Ovarian carcinoma (B)</p> Signup and view all the answers

What is a key characteristic of malignant tumors?

<p>Rapid growth and infiltration (D)</p> Signup and view all the answers

What is a characteristic feature of benign tumors?

<p>Low nuclear to cytoplasmic ratio (B)</p> Signup and view all the answers

What is the hallmark of malignancy?

<p>Metastatic potential (D)</p> Signup and view all the answers

What is the purpose of immunohistochemistry in tumor characterization?

<p>To characterize tumors that are difficult to classify on histology (D)</p> Signup and view all the answers

What is the importance of grading in cancer assessment?

<p>Determining prognosis based on differentiation (B)</p> Signup and view all the answers

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