15 Questions
What is the definition of a tumor (neoplasia)?
A new growth of tissue that usually forms a mass
What is a malignant neoplasm?
A cancerous growth
How do cancer cells differ from normal cells?
They can ignore apoptotic signals
What is the main cause of DNA damage leading to cancer?
Endogenous causes such as reactive oxygen species (ROS)
What is the pathogenesis of cancer?
Due to an interaction between environmental factors and a genetically susceptible host
Which term describes a new growth of tissue that usually forms a mass?
Tumor
What is the Greek origin of the term 'Neoplasia'?
Neo: new & plasia: formation
What distinguishes cancer cells from normal cells?
They lose their ability to stop dividing and to die at the proper time
Which of the following is not an environmental factor causing DNA damage leading to cancer?
Normal cellular metabolism
What is the main cause of an interaction leading to cancer?
Interaction between environmental factors and a genetically susceptible host
What is the Greek meaning of the term 'Neoplasia'?
New formation
What is the main cause of DNA damage leading to cancer?
Random injury during DNA replication
What distinguishes cancer cells from normal cells?
Influence on the surrounding microenvironment
What is the definition of a malignant neoplasm?
Cancer
What is the pathogenesis of cancer primarily due to?
Interaction between environmental and genetic factors
Study Notes
Definition of Neoplasia
- A tumor or neoplasia is a new growth of tissue that usually forms a mass, resulting from abnormal cell proliferation.
Malignant Neoplasm
- A malignant neoplasm is a type of tumor that is cancerous, meaning it has the ability to invade and spread to other parts of the body.
Characteristics of Cancer Cells
- Cancer cells differ from normal cells in that they exhibit uncontrolled growth, do not respond to growth-regulating signals, and can invade and spread to other parts of the body.
- Cancer cells are characterized by genetic mutations, altered gene expression, and abnormal cell division.
Causes of DNA Damage
- The main cause of DNA damage leading to cancer is genetic mutations resulting from environmental factors, such as radiation, viruses, and carcinogens.
Pathogenesis of Cancer
- The pathogenesis of cancer is primarily due to genetic mutations, which lead to the uncontrolled growth and proliferation of abnormal cells.
- The process of cancer development involves initiation, promotion, and progression stages.
Etymology of Neoplasia
- The term "Neoplasia" has a Greek origin, meaning "new growth" or "new formation".
- The Greek meaning of the term "Neoplasia" is a new growth of tissue.
Distinctive Features of Cancer Cells
- What distinguishes cancer cells from normal cells is their ability to invade and spread to other parts of the body, and their uncontrolled growth.
Environmental Factors
- Environmental factors that can cause DNA damage leading to cancer include radiation, viruses, and carcinogens.
- The main cause of an interaction leading to cancer is the exposure to environmental factors that damage DNA.
Test your knowledge of tumors and neoplasia with this quiz. Explore the definitions and characteristics of tumors, neoplasia, and cancer, along with the pathogenesis of cancer.
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