Podcast
Questions and Answers
What action should be taken in response to minor side effects caused by Isoniazide?
What action should be taken in response to minor side effects caused by Isoniazide?
- Change to a different medication
- Adjust the dosage and prescribe pyridoxine (correct)
- Increase the dosage for better effect
- Stop the treatment immediately
Which of the following is NOT a major side effect associated with Rifampicine?
Which of the following is NOT a major side effect associated with Rifampicine?
- Nausea (correct)
- Purpura
- Anuria
- Hepatitis with jaundice
In which situation is Prednisolone NOT indicated?
In which situation is Prednisolone NOT indicated?
- Acute hematological miliary
- Tuberculosis of serous membranes
- Mediastinal adenopathy with ventilation trouble
- Severe allergic reaction to medications (correct)
What is the required action for patients experiencing optic neuritis due to Ethambutol?
What is the required action for patients experiencing optic neuritis due to Ethambutol?
Which statement correctly describes the effectiveness of the tuberculosis treatment?
Which statement correctly describes the effectiveness of the tuberculosis treatment?
Which factor is NOT considered a risk factor for tuberculosis?
Which factor is NOT considered a risk factor for tuberculosis?
What type of tuberculosis infection is characterized as latent?
What type of tuberculosis infection is characterized as latent?
Which agent is primarily responsible for tuberculous infections in humans?
Which agent is primarily responsible for tuberculous infections in humans?
What is the method of indirect contamination of tuberculosis?
What is the method of indirect contamination of tuberculosis?
Which statement regarding the epidemiology of tuberculosis is correct?
Which statement regarding the epidemiology of tuberculosis is correct?
Which condition does NOT significantly affect tuberculosis severity?
Which condition does NOT significantly affect tuberculosis severity?
What is the primary mode of direct transmission of tuberculosis?
What is the primary mode of direct transmission of tuberculosis?
What characterizes miliary tuberculosis?
What characterizes miliary tuberculosis?
What is typically observed in the thoracic radiography of pulmonary tuberculosis?
What is typically observed in the thoracic radiography of pulmonary tuberculosis?
Which laboratory finding is most associated with pleural tuberculosis?
Which laboratory finding is most associated with pleural tuberculosis?
For abdominal tuberculosis, which clinical feature can present diagnostic challenges?
For abdominal tuberculosis, which clinical feature can present diagnostic challenges?
What symptom is prominently associated with respiratory tuberculosis?
What symptom is prominently associated with respiratory tuberculosis?
Which age group has the lowest incidence of pleural effusion associated with tuberculosis?
Which age group has the lowest incidence of pleural effusion associated with tuberculosis?
How is tuberculous meningitis typically diagnosed?
How is tuberculous meningitis typically diagnosed?
What condition can be misdiagnosed as lymphoma when considering mesenteric tuberculosis?
What condition can be misdiagnosed as lymphoma when considering mesenteric tuberculosis?
What is the characteristic finding in the thoracic X-ray of miliary tuberculosis?
What is the characteristic finding in the thoracic X-ray of miliary tuberculosis?
Which complication can arise due to abdominal tuberculosis?
Which complication can arise due to abdominal tuberculosis?
What is the most significant characteristic of tuberculosis in children?
What is the most significant characteristic of tuberculosis in children?
Which of the following correctly describes the immune response to inhaled BK that is not completely destroyed?
Which of the following correctly describes the immune response to inhaled BK that is not completely destroyed?
What does a lymphatic and hematogenous dissemination of tuberculosis most likely result in?
What does a lymphatic and hematogenous dissemination of tuberculosis most likely result in?
Which factor indicates a latent primary infection of tuberculosis?
Which factor indicates a latent primary infection of tuberculosis?
What type of lesions are commonly observed in the elementary lesions of tuberculosis?
What type of lesions are commonly observed in the elementary lesions of tuberculosis?
What is the primary radiological finding in primary tuberculosis infection?
What is the primary radiological finding in primary tuberculosis infection?
Which of the following symptoms is NOT typically associated with symptoms of tuberculosis?
Which of the following symptoms is NOT typically associated with symptoms of tuberculosis?
What is a potential consequence of caseification followed by liquefaction in TB infections?
What is a potential consequence of caseification followed by liquefaction in TB infections?
In a latent tuberculosis infection, which of the following characteristics would be observed?
In a latent tuberculosis infection, which of the following characteristics would be observed?
What is the recommended treatment regimen for a patient with pulmonary tuberculosis that has a positive smear?
What is the recommended treatment regimen for a patient with pulmonary tuberculosis that has a positive smear?
Which medication should not be prescribed without a pre-treatment ophthalmological examination?
Which medication should not be prescribed without a pre-treatment ophthalmological examination?
In the treatment of tuberculous meningitis, which is the correct treatment phase and duration?
In the treatment of tuberculous meningitis, which is the correct treatment phase and duration?
What is the maximum dosage of Isoniazide (H) per day for adults in the treatment of tuberculosis?
What is the maximum dosage of Isoniazide (H) per day for adults in the treatment of tuberculosis?
Which of the following combinations is appropriate for treating a child weighing less than 25 kg?
Which of the following combinations is appropriate for treating a child weighing less than 25 kg?
What is the recommended follow-up duration for checking the weight and clinical examination post-treatment initiation?
What is the recommended follow-up duration for checking the weight and clinical examination post-treatment initiation?
Which condition would require a personalized treatment due to resistance?
Which condition would require a personalized treatment due to resistance?
What is the recommended initial treatment for pleural effusion due to tuberculosis?
What is the recommended initial treatment for pleural effusion due to tuberculosis?
What is the correct maximum dose of Pyrazinamide (Z) for adults?
What is the correct maximum dose of Pyrazinamide (Z) for adults?
Which of the following is NOT a reason to conduct a pre-therapeutic assessment?
Which of the following is NOT a reason to conduct a pre-therapeutic assessment?
Flashcards
Tuberculosis Infection (Latent Infection)
Tuberculosis Infection (Latent Infection)
The initial stage of tuberculosis infection where the bacteria are present in the body but not causing symptoms. The immune system is able to control the infection, preventing it from spreading.
Tuberculosis Disease (Active Infection)
Tuberculosis Disease (Active Infection)
The active form of tuberculosis infection where the bacteria are multiplying and causing symptoms. This stage can affect the lungs, but also other parts of the body.
Pulmonary Tuberculosis
Pulmonary Tuberculosis
Tuberculosis that affects the lungs. It is the most common type of tuberculosis.
Extra-pulmonary Tuberculosis
Extra-pulmonary Tuberculosis
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Tuberculosis Transmission
Tuberculosis Transmission
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Tuberculosis Risk Factors
Tuberculosis Risk Factors
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Mycobacterium tuberculosis
Mycobacterium tuberculosis
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Miliary Tuberculosis
Miliary Tuberculosis
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Post Primary Tuberculosis
Post Primary Tuberculosis
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Pleural Tuberculosis
Pleural Tuberculosis
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Abdominal Tuberculosis
Abdominal Tuberculosis
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Mesenteric Lymph Node Tuberculosis
Mesenteric Lymph Node Tuberculosis
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Peritoneal Tuberculosis
Peritoneal Tuberculosis
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Intestinal Tuberculosis
Intestinal Tuberculosis
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Micronodules in the lungs
Micronodules in the lungs
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Cerebrospinal Fluid (CSF) Analysis
Cerebrospinal Fluid (CSF) Analysis
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Ganglionar Reaction
Ganglionar Reaction
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Hematogenous Dissemination
Hematogenous Dissemination
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Meninges
Meninges
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Bones
Bones
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Kidney
Kidney
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Tuberculous Follicle
Tuberculous Follicle
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Primary Tuberculosis
Primary Tuberculosis
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Latent Tuberculosis Infection
Latent Tuberculosis Infection
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What are minor side effects of anti-TB drugs?
What are minor side effects of anti-TB drugs?
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What are major side effects of anti-TB drugs?
What are major side effects of anti-TB drugs?
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What is the role of Prednisolone in managing tuberculosis?
What is the role of Prednisolone in managing tuberculosis?
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What is the role of respiratory physiotherapy in tuberculosis management?
What is the role of respiratory physiotherapy in tuberculosis management?
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When is surgical intervention considered in tuberculosis?
When is surgical intervention considered in tuberculosis?
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Tuberculosis Medication Schedule
Tuberculosis Medication Schedule
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2RHZE Phase
2RHZE Phase
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2RH or 4RH Phase
2RH or 4RH Phase
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Treatment Regimen
Treatment Regimen
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Mediastinal Lymphadenitis
Mediastinal Lymphadenitis
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Superficial Tuberculous Lymphadenitis
Superficial Tuberculous Lymphadenitis
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Tuberculous Pleural Effusion
Tuberculous Pleural Effusion
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Multi-drug Resistant Tuberculosis
Multi-drug Resistant Tuberculosis
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Tuberculous Meningitis
Tuberculous Meningitis
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Study Notes
Introduction
- Tuberculosis (TB) in children is a significant public health concern.
- TB is a preventable and curable disease.
- Diagnosis is challenging, relying on a combination of factors.
- Prevalence is moderate in Algeria, with a focus on children under 15 years old, ranging from 7-10%.
- Risk factors include family history, high-incidence areas, poverty, overcrowding, unsanitary conditions, and HIV infection.
- Malnutrition is also a contributing factor.
Epidemiology
- One-third of the global population is infected with Mycobacterium tuberculosis (TB).
- Globally, 9.3 million new cases and 1.8 million deaths occur yearly.
- There's declining prevalence in developed countries, but it remains a major concern.
- TB is one of the most common infectious diseases in terms of morbidity and mortality, especially in context of HIV-positive status.
Pathophysiology
- The main pathogen is Mycobacterium tuberculosis complex, primarily Mycobacterium tuberculosis.
- Transmission is airborne through respiratory droplets.
- Initial infection involves phagocytosis by alveolar macrophages, leading to potential immunity or progression.
- Chronic infection can result in the formation of tubercles, possible spread via lymphatic and blood systems, and subsequent reactivation.
- Different forms exist based on localization and severity.
Diagnostic
- Latent infection can be detected via the Mantoux test.
- Active disease can be diagnosed using a combination of clinical symptoms, radiological findings, and laboratory tests.
- Differentiation between latent and active TB is crucial.
- Accurate diagnosis requires careful evaluation of clinical presentation.
- Particular attention is given to children, as presentations may differ from adults.
Treatment
- First-line anti-TB drugs are used initially.
- Treatment plans vary dependent on TB type and severity.
- Adjuvant therapies may be necessary.
- Adherence to the full treatment regimen is critical to avoid drug resistance.
- Patient monitoring is essential for managing treatment side effects.
Prevention
- Vaccination (BCG) is a crucial component of TB prevention.
- Early detection and treatment of TB in community members are essential to reduce transmission.
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