Tricyclic Antidepressants

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Questions and Answers

What is the first step in synaptic transmission?

  • Neurotransmitter is released into the synapse (correct)
  • Neurotransmitter binds to receptors
  • Post-synaptic potential is generated
  • Reuptake of neurotransmitter

Neurotransmitters always inhibit the post-synaptic neuron.

False (B)

What type of drug blocks the reuptake of neurotransmitters?

Tricyclic antidepressant

The space between two neurons is called the ______.

<p>synapse</p> Signup and view all the answers

What type of neurotransmitter is serotonin?

<p>Either excitatory or inhibitory neurotransmitter (C)</p> Signup and view all the answers

Blocking neurotransmitter reuptake decreases the concentration of neurotransmitter in the synapse.

<p>False (B)</p> Signup and view all the answers

What is the direct result of increased synaptic concentration of neurotransmitters?

<p>Increased post-synaptic nerve transmission (B)</p> Signup and view all the answers

What is the role of post-synaptic receptors?

<p>To bind neurotransmitters (C)</p> Signup and view all the answers

Serotonin and norepinephrine are examples of ______.

<p>neurotransmitters</p> Signup and view all the answers

Neurotransmitters are only released from the post-synaptic neuron.

<p>False (B)</p> Signup and view all the answers

Flashcards

What is a synapse?

The point of communication between two neurons, where neurotransmitters are released.

What are neurotransmitters?

Chemical messengers that transmit signals across a synapse from one neuron to another.

What is neurotransmitter reuptake?

The process where neurotransmitters are taken back into the presynaptic neuron after transmitting a signal.

What happens when reuptake is blocked?

This occurs when neurotransmitter reuptake is blocked, leading to higher concentrations in the synapse.

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What are serotonin/norepinephrine?

Neurotransmitters like serotonin or norepinephrine are released into the synapse.

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What does a neurotransmitter do after release?

It activates the receptors in the postsynaptic neuron.

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How does blocking reuptake impact neurotransmitters?

Blocking reuptake increases the concentration available to bind to receptors.

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Blocking reuptake effect?

Blocking neurotransmitter reuptake results in increased signaling between neurons.

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Study Notes

  • Synapse is the space where neurotransmitters are released
  • Neurotransmitters are released into the synapse
  • Neurotransmitters activate post-synaptic receptors
  • Tricyclic antidepressants block the reuptake of neurotransmitters
  • Increased synaptic concentration of neurotransmitters are available to bind to the post-synaptic receptors
  • Increased post-synaptic nerve transmission occurs as a result of increased synaptic concentration of neurotransmitters that bind to receptors
  • Neurotransmitters include serotonin or norepinephrine

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