L8 Transport of O2

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Questions and Answers

What is the volume of oxygen in ml present in chemical combination with Hb in 100ml blood when fully saturated?

  • 10 ml
  • 30 ml
  • 25 ml (correct)
  • 15 ml

Which factor determines the rate and direction of oxygen diffusion in the blood?

  • Carbon dioxide content
  • Oxygen tension (correct)
  • Oxygen content
  • Diffusion coefficient

What is the nature of oxygen when it combines with iron (Fe+2) of hemoglobin?

  • HbO2 (correct)
  • HbO4
  • HbO8
  • HbO6

Which form of oxygen constitutes about 2% in blood?

<p><strong>O2 in physical solution</strong> (D)</p> Signup and view all the answers

What determines the percentage of hemoglobin saturation?

<p><strong>Oxygen tension</strong> (B)</p> Signup and view all the answers

What is the volume of oxygen in ml present in 100ml arterial blood with a PO2 of 100mmHg?

<p><strong>0.3 ml</strong> (D)</p> Signup and view all the answers

Which compound determines the O2 capacity and O2 content present in blood?

<p><strong>Hemoglobin</strong> (C)</p> Signup and view all the answers

What is the shape of the myoglobin dissociation curve?

<p>Rectangular hyperbola (B)</p> Signup and view all the answers

At what pO2 level is myoglobin fully saturated with oxygen during rest?

<p>40 mmHg (A)</p> Signup and view all the answers

What is the role of myoglobin in skeletal muscle?

<p>It acts as an oxygen store (D)</p> Signup and view all the answers

What happens to myoglobin's oxygen during muscle exercise?

<p>It decreases (A)</p> Signup and view all the answers

In which form does myoglobin combine with oxygen?

<p>Cubic (C)</p> Signup and view all the answers

What happens to the p50 value in a left shift of the oxygen dissociation curve?

<p>It decreases (B)</p> Signup and view all the answers

What tests should be ordered to calculate a patient's blood oxygen concentration?

<p>Blood draw, arterial blood gas, pulse oximetry, hemoglobin level (C)</p> Signup and view all the answers

What kind of pigment is myoglobin?

<p>Iron-containing pigment (C)</p> Signup and view all the answers

At what tissue level does myoglobin give its oxygen to the muscles?

<p>pO2 below 40 mmHg (C)</p> Signup and view all the answers

At which partial pressure of oxygen (PO2) does hemoglobin (Hb) become 90% saturated with oxygen?

<p>$PO_2 = 60$ mmHg (D)</p> Signup and view all the answers

What is the oxygen content of arterial blood at a $PO_2$ of 100 mmHg?

<p>19 ml/100 ml blood (B)</p> Signup and view all the answers

What is the percentage of hemoglobin saturation with oxygen in venous blood at a $PO_2$ of 40 mmHg?

<p>70% (C)</p> Signup and view all the answers

Which part of the oxygen-hemoglobin dissociation curve represents the release of oxygen to tissues?

<p>The steep portion (D)</p> Signup and view all the answers

What is the significance of the sigmoid shape of the oxygen-hemoglobin dissociation curve?

<p>It allows easy and almost complete saturation of hemoglobin at the lungs, even when oxygen tension is low. (D)</p> Signup and view all the answers

At high altitudes, what is the approximate partial pressure of oxygen (PO2) in the lungs?

<p>$PO_2 = 60$ mmHg (C)</p> Signup and view all the answers

What is the oxygen capacity of hemoglobin?

<p>20 ml/100 ml blood (B)</p> Signup and view all the answers

What is the primary function of the steep portion of the oxygen-hemoglobin dissociation curve?

<p>To allow easy and rapid release of oxygen from hemoglobin to the tissues at low partial pressures of oxygen (B)</p> Signup and view all the answers

What is the significance of the p50 value in the oxygen-hemoglobin dissociation curve?

<p>It represents the partial pressure of oxygen at which hemoglobin is 50% saturated with oxygen (B)</p> Signup and view all the answers

Which of the following factors causes a right shift in the oxygen-hemoglobin dissociation curve, decreasing the affinity of hemoglobin for oxygen?

<p>All of the above (D)</p> Signup and view all the answers

What is the effect of a left shift in the oxygen-hemoglobin dissociation curve?

<p>Increased affinity of hemoglobin for oxygen, leading to decreased oxygen release to tissues (D)</p> Signup and view all the answers

Which form of hemoglobin has a higher affinity for oxygen?

<p>Relaxed form (C)</p> Signup and view all the answers

What is the effect of carbon monoxide poisoning on the oxygen-hemoglobin dissociation curve?

<p>It causes a left shift in the curve (B)</p> Signup and view all the answers

Which of the following statements is true about the shape of the oxygen-hemoglobin dissociation curve?

<p>The S-shape is due to the presence of four heme groups in hemoglobin, each with different affinities for oxygen (B)</p> Signup and view all the answers

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