L8 Transport of O2
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Questions and Answers

What is the volume of oxygen in ml present in chemical combination with Hb in 100ml blood when fully saturated?

  • 10 ml
  • 30 ml
  • 25 ml (correct)
  • 15 ml

    • Which factor determines the rate and direction of oxygen diffusion in the blood?

  • Carbon dioxide content
  • Oxygen tension (correct)
  • Oxygen content
  • Diffusion coefficient

    • What is the nature of oxygen when it combines with iron (Fe+2) of hemoglobin?

  • HbO2 (correct)
  • HbO4
  • HbO8
  • HbO6

    • Which form of oxygen constitutes about 2% in blood?

    <p><strong>O2 in physical solution</strong></p> Signup and view all the answers

    What determines the percentage of hemoglobin saturation?

    <p><strong>Oxygen tension</strong></p> Signup and view all the answers

    What is the volume of oxygen in ml present in 100ml arterial blood with a PO2 of 100mmHg?

    <p><strong>0.3 ml</strong></p> Signup and view all the answers

    Which compound determines the O2 capacity and O2 content present in blood?

    <p><strong>Hemoglobin</strong></p> Signup and view all the answers

    What is the shape of the myoglobin dissociation curve?

    <p>Rectangular hyperbola</p> Signup and view all the answers

    At what pO2 level is myoglobin fully saturated with oxygen during rest?

    <p>40 mmHg</p> Signup and view all the answers

    What is the role of myoglobin in skeletal muscle?

    <p>It acts as an oxygen store</p> Signup and view all the answers

    What happens to myoglobin's oxygen during muscle exercise?

    <p>It decreases</p> Signup and view all the answers

    In which form does myoglobin combine with oxygen?

    <p>Cubic</p> Signup and view all the answers

    What happens to the p50 value in a left shift of the oxygen dissociation curve?

    <p>It decreases</p> Signup and view all the answers

    What tests should be ordered to calculate a patient's blood oxygen concentration?

    <p>Blood draw, arterial blood gas, pulse oximetry, hemoglobin level</p> Signup and view all the answers

    What kind of pigment is myoglobin?

    <p>Iron-containing pigment</p> Signup and view all the answers

    At what tissue level does myoglobin give its oxygen to the muscles?

    <p>pO2 below 40 mmHg</p> Signup and view all the answers

    At which partial pressure of oxygen (PO2) does hemoglobin (Hb) become 90% saturated with oxygen?

    <p>$PO_2 = 60$ mmHg</p> Signup and view all the answers

    What is the oxygen content of arterial blood at a $PO_2$ of 100 mmHg?

    <p>19 ml/100 ml blood</p> Signup and view all the answers

    What is the percentage of hemoglobin saturation with oxygen in venous blood at a $PO_2$ of 40 mmHg?

    <p>70%</p> Signup and view all the answers

    Which part of the oxygen-hemoglobin dissociation curve represents the release of oxygen to tissues?

    <p>The steep portion</p> Signup and view all the answers

    What is the significance of the sigmoid shape of the oxygen-hemoglobin dissociation curve?

    <p>It allows easy and almost complete saturation of hemoglobin at the lungs, even when oxygen tension is low.</p> Signup and view all the answers

    At high altitudes, what is the approximate partial pressure of oxygen (PO2) in the lungs?

    <p>$PO_2 = 60$ mmHg</p> Signup and view all the answers

    What is the oxygen capacity of hemoglobin?

    <p>20 ml/100 ml blood</p> Signup and view all the answers

    What is the primary function of the steep portion of the oxygen-hemoglobin dissociation curve?

    <p>To allow easy and rapid release of oxygen from hemoglobin to the tissues at low partial pressures of oxygen</p> Signup and view all the answers

    What is the significance of the p50 value in the oxygen-hemoglobin dissociation curve?

    <p>It represents the partial pressure of oxygen at which hemoglobin is 50% saturated with oxygen</p> Signup and view all the answers

    Which of the following factors causes a right shift in the oxygen-hemoglobin dissociation curve, decreasing the affinity of hemoglobin for oxygen?

    <p>All of the above</p> Signup and view all the answers

    What is the effect of a left shift in the oxygen-hemoglobin dissociation curve?

    <p>Increased affinity of hemoglobin for oxygen, leading to decreased oxygen release to tissues</p> Signup and view all the answers

    Which form of hemoglobin has a higher affinity for oxygen?

    <p>Relaxed form</p> Signup and view all the answers

    What is the effect of carbon monoxide poisoning on the oxygen-hemoglobin dissociation curve?

    <p>It causes a left shift in the curve</p> Signup and view all the answers

    Which of the following statements is true about the shape of the oxygen-hemoglobin dissociation curve?

    <p>The S-shape is due to the presence of four heme groups in hemoglobin, each with different affinities for oxygen</p> Signup and view all the answers

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