14 Questions
What is the main characteristic of graft rejection?
It leads to the destruction of the transplanted tissue
Which type of mice exhibit no functional, mature T-cells due to a lack of thymus?
Nude mice
What is the role of CD4+ and CD8+ cells in graft rejection?
Both CD4+ and CD8+ cells have a role in graft rejection
Which pathway involves T cell recognition of intact alloantigen on host dendritic cells?
Direct pathway
What must be minimized to reduce the chances of rejection in transplantation?
HLA matching between donor and recipient
What does graft rejection display in terms of specificity and memory?
Specificity and memory
What is the key characteristic of graft rejection?
Memory and specificity in destruction of tissue
In graft rejection, which pathway involves recipient T cells recognizing allogeneic MHC plus associated peptides directly?
Direct pathway
What is the role of dendritic cells in graft rejection?
Initiate direct allorecognition in the recipient
What is the consequence of removing both CD4+ and CD8+ cells in graft rejection?
Increased chances of survival of allografts
Why is it important for the donor to be as close as possible in HLA match to the recipient in transplantation?
To promote graft acceptance
What is the main characteristic of Nude mice regarding graft rejection?
'T-cell Deficient' due to lack of thymus
What type of mice exhibit no functional, mature T-cells due to a lack of thymus?
'Nude' mice
Why must a patient take immunosuppressive treatment post-transplantation?
To prevent graft rejection
Test your knowledge about the act of transferring cells, tissues, and organs from one site to another through this quiz on different types of transplants.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
