Podcast
Questions and Answers
What is a result of cancer cells dividing rapidly?
What is a result of cancer cells dividing rapidly?
- The immune system can kill cancer cells more effectively
- The immune system is suppressed, but cancer cells still grow slowly
- The rate of cancer cell growth is slower than the immune system's response
- The immune system is outpaced, allowing cancer cells to dominate (correct)
What happens when tumors stop expressing antigens targeted by the immune response?
What happens when tumors stop expressing antigens targeted by the immune response?
- T and B cells become more effective at killing cancer cells
- The immune system targets other antigens
- T and B cells are unable to kill cancer cells (correct)
- The immune system stops responding to cancer cells
What is the role of MHC I in antigen recognition?
What is the role of MHC I in antigen recognition?
- It helps CTLs recognize extracellular microbes
- It helps CTLs recognize cytoplasmic microbes or cancer (correct)
- It helps B cells recognize antigens
- It helps NK cells recognize target cells
What is the consequence of losing MHC I expression in cancer cells?
What is the consequence of losing MHC I expression in cancer cells?
What is the result of granzymes being delivered to the target cell?
What is the result of granzymes being delivered to the target cell?
What is a characteristic of more invasive and metastatic cancers?
What is a characteristic of more invasive and metastatic cancers?
Why is hyperacute rejection not a common problem in clinical transplantation?
Why is hyperacute rejection not a common problem in clinical transplantation?
What is the primary cause of early graft failure?
What is the primary cause of early graft failure?
What type of cells may react against cells in graft vessels, leading to vascular damage?
What type of cells may react against cells in graft vessels, leading to vascular damage?
What is the main mechanism of antibody-mediated injury to graft vessels?
What is the main mechanism of antibody-mediated injury to graft vessels?
What is the primary goal of current immunosuppressive therapy in transplantation?
What is the primary goal of current immunosuppressive therapy in transplantation?
What is a characteristic of chronic rejection?
What is a characteristic of chronic rejection?
What triggers the release of DAMPs in cancer?
What triggers the release of DAMPs in cancer?
What is the role of receptors on APCs?
What is the role of receptors on APCs?
What is the result of cross presentation of cancer antigens?
What is the result of cross presentation of cancer antigens?
Why does the immune system often fail to eliminate cancer cells?
Why does the immune system often fail to eliminate cancer cells?
What type of cells play a critical role in the response to cancer-associated antigens?
What type of cells play a critical role in the response to cancer-associated antigens?
What is the fate of activated APCs?
What is the fate of activated APCs?
What is the primary concern in transplant patients?
What is the primary concern in transplant patients?
What type of transplant occurs between animals of the same species but not genetically identical?
What type of transplant occurs between animals of the same species but not genetically identical?
What is the typical lifespan of tissue valves made from pig heart valves or cow heart-sac tissue?
What is the typical lifespan of tissue valves made from pig heart valves or cow heart-sac tissue?
What is the term for tissue from another individual of the same species?
What is the term for tissue from another individual of the same species?
Why are tissue valves preferred over mechanical valves for those over 70?
Why are tissue valves preferred over mechanical valves for those over 70?
What is the term for a transplant from one's own tissue?
What is the term for a transplant from one's own tissue?
What occurs when T cells in the recipient recognize donor allogeneic MHC molecules on graft dendritic cells?
What occurs when T cells in the recipient recognize donor allogeneic MHC molecules on graft dendritic cells?
What is the main difference between direct and indirect allorecognition?
What is the main difference between direct and indirect allorecognition?
What is the outcome of indirect recognition of alloantigens?
What is the outcome of indirect recognition of alloantigens?
What is the main mediator of graft rejection in indirect allorecognition?
What is the main mediator of graft rejection in indirect allorecognition?
What is the role of dendritic cells in direct allorecognition?
What is the role of dendritic cells in direct allorecognition?
What is the result of direct recognition of alloantigens?
What is the result of direct recognition of alloantigens?
What is the role of the immune system in preventing cancer?
What is the role of the immune system in preventing cancer?
What is the concept of immune surveillance?
What is the concept of immune surveillance?
What is the evidence of immune surveillance in humans?
What is the evidence of immune surveillance in humans?
What is the result of stimulating the immune system by blocking inhibitory receptors in some cancer types?
What is the result of stimulating the immune system by blocking inhibitory receptors in some cancer types?
What is the increased risk of cancer associated with?
What is the increased risk of cancer associated with?
What is the role of T cells and antibodies in cancer?
What is the role of T cells and antibodies in cancer?
What is the primary concern in a cancer patient versus a transplant patient?
What is the primary concern in a cancer patient versus a transplant patient?
What is the term for a transplant between animals identical to one another?
What is the term for a transplant between animals identical to one another?
What type of valves are typically used for people over 70?
What type of valves are typically used for people over 70?
What is the term for tissue from a different species?
What is the term for tissue from a different species?
What is the typical lifespan of tissue valves made from pig heart valves or cow heart-sac tissue?
What is the typical lifespan of tissue valves made from pig heart valves or cow heart-sac tissue?
What is the purpose of using pig heart valves in human transplants?
What is the purpose of using pig heart valves in human transplants?
What is the role of FasL in the tumor environment?
What is the role of FasL in the tumor environment?
What is the goal of stimulating the host's immune response to combat cancer?
What is the goal of stimulating the host's immune response to combat cancer?
How do monoclonal antibodies work in passive immunotherapy?
How do monoclonal antibodies work in passive immunotherapy?
What is the main difference between traditional cancer treatments and immunotherapy?
What is the main difference between traditional cancer treatments and immunotherapy?
What are the three main approaches to modern immunotherapy?
What are the three main approaches to modern immunotherapy?
What is the limitation of traditional cancer treatments?
What is the limitation of traditional cancer treatments?
What is a common symptom of GvHD?
What is a common symptom of GvHD?
What is the goal of immunosuppressive therapy in transplantation?
What is the goal of immunosuppressive therapy in transplantation?
What is a consequence of immunosuppressive therapy in transplantation?
What is a consequence of immunosuppressive therapy in transplantation?
What is the role of the immune system in cancer?
What is the role of the immune system in cancer?
What is the term for the process by which the immune system targets cancer cells?
What is the term for the process by which the immune system targets cancer cells?
What is a type of therapy that modulates the immune system to fight cancer?
What is a type of therapy that modulates the immune system to fight cancer?
What is the goal of tumor vaccines?
What is the goal of tumor vaccines?
What type of vaccines are given to individuals before they are infected with a virus?
What type of vaccines are given to individuals before they are infected with a virus?
What type of cells are expanded ex vivo and exposed to tumor cells or a defined tumor antigen in a tumor vaccine approach?
What type of cells are expanded ex vivo and exposed to tumor cells or a defined tumor antigen in a tumor vaccine approach?
What is the result of vaccination against oncogenic viruses?
What is the result of vaccination against oncogenic viruses?
Why have tumor vaccines achieved only modest success?
Why have tumor vaccines achieved only modest success?
What is the relation between transplantation and the immune response?
What is the relation between transplantation and the immune response?
Flashcards are hidden until you start studying
