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Questions and Answers
Which enzyme is required to activate the transcription factor NFAT in T cells?
Which enzyme is required to activate the transcription factor NFAT in T cells?
- Protein kinase A
- Protein phosphatase calcineurin (correct)
- Protein kinase C
- Kinase mTOR
Which class of immunosuppressive drugs include cyclosporine and tacrolimus?
Which class of immunosuppressive drugs include cyclosporine and tacrolimus?
- mTOR inhibitors
- Protein kinase C inhibitors
- Calcineurin inhibitors (correct)
- Protein kinase A inhibitors
Which drug inhibits a kinase called mTOR required for T cell activation?
Which drug inhibits a kinase called mTOR required for T cell activation?
- Rapamycin (correct)
- Tacrolimus
- Cyclosporine
- Azathioprine
Which type of organ transplant does not require HLA matching?
Which type of organ transplant does not require HLA matching?
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What is the main goal of transplant immunologists?
What is the main goal of transplant immunologists?
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What is the frequent cause of xenotransplant loss?
What is the frequent cause of xenotransplant loss?
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What is the histologic appearance of acute rejection?
What is the histologic appearance of acute rejection?
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