Immunosuppression and Organ Transplantation Quiz
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Questions and Answers

Which enzyme is required to activate the transcription factor NFAT in T cells?

  • Protein kinase A
  • Protein phosphatase calcineurin (correct)
  • Protein kinase C
  • Kinase mTOR
  • Which class of immunosuppressive drugs include cyclosporine and tacrolimus?

  • mTOR inhibitors
  • Protein kinase C inhibitors
  • Calcineurin inhibitors (correct)
  • Protein kinase A inhibitors
  • Which drug inhibits a kinase called mTOR required for T cell activation?

  • Rapamycin (correct)
  • Tacrolimus
  • Cyclosporine
  • Azathioprine
  • Which type of organ transplant does not require HLA matching?

    <p>Heart</p> Signup and view all the answers

    What is the main goal of transplant immunologists?

    <p>To induce immunological tolerance specifically for the graft alloantigens</p> Signup and view all the answers

    What is the frequent cause of xenotransplant loss?

    <p>Hyperacute rejection</p> Signup and view all the answers

    What is the histologic appearance of acute rejection?

    <p>Humoral (antibody-mediated) rejection</p> Signup and view all the answers

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