7 Questions
Which enzyme is required to activate the transcription factor NFAT in T cells?
Protein phosphatase calcineurin
Which class of immunosuppressive drugs include cyclosporine and tacrolimus?
Calcineurin inhibitors
Which drug inhibits a kinase called mTOR required for T cell activation?
Rapamycin
Which type of organ transplant does not require HLA matching?
Heart
What is the main goal of transplant immunologists?
To induce immunological tolerance specifically for the graft alloantigens
What is the frequent cause of xenotransplant loss?
Hyperacute rejection
What is the histologic appearance of acute rejection?
Humoral (antibody-mediated) rejection
Test your knowledge on immunosuppression and organ transplantation with this quiz. Explore the impact of immunosuppressive drugs in preventing organ rejection and the advances they have brought to the field of transplantation.
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