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Transfusion Reactions
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Transfusion Reactions

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Questions and Answers

What is the main cause of Acute Hemolytic Transfusion Reaction?

ABO incompatibility between donor and recipient blood

What is the treatment for Febrile Non-Hemolytic Transfusion Reaction (FNHTR)?

Antipyretics and supportive care

What is the main cause of Transfusion-Associated Graft-Versus-Host Disease (TA-GVHD)?

Engraftment of donor T-lymphocytes

What is the treatment for Post-Transfusion Purpura (PTP)?

<p>Platelet transfusions and immunoglobulin therapy</p> Signup and view all the answers

What is the main cause of Delayed Hemolytic Transfusion Reaction?

<p>Anamnestic response to previously sensitized recipient</p> Signup and view all the answers

What is the treatment for Allergic Transfusion Reaction?

<p>Antihistamines and supportive care</p> Signup and view all the answers

What are the two essential steps to verify before administering blood products to a patient?

<p>Verify patient identification and blood product compatibility, and check blood product expiration date and integrity</p> Signup and view all the answers

What is the recommended needle size for adult patients during blood administration?

<p>19-23 gauge</p> Signup and view all the answers

What is the initial infusion rate for blood administration, and what is the purpose of this rate?

<p>1-2 mL/min for 15 minutes, to monitor for any adverse reactions</p> Signup and view all the answers

What are the signs of transfusion reaction that healthcare professionals should monitor for during and after blood administration?

<p>Fever, chills, hives, flushing, hypotension, and tachycardia</p> Signup and view all the answers

What type of blood products may be used for patients with a history of allergic reactions?

<p>Washed RBCs or leukoreduced RBCs</p> Signup and view all the answers

What should be done if a transfusion reaction occurs during blood administration?

<p>Stop the infusion and notify the physician</p> Signup and view all the answers

Study Notes

Transfusion Reactions

Transfusion reactions occur when the recipient's immune system reacts to the transfused blood, leading to adverse effects. These reactions can be acute or delayed.

Acute Transfusion Reactions

  • Febrile Non-Hemolytic Transfusion Reaction (FNHTR)
    • Caused by recipient's immune response to donor leukocytes
    • Symptoms: fever, chills, and discomfort
    • Treatment: antipyretics and supportive care
  • Allergic Transfusion Reaction
    • Caused by recipient's immune response to donor plasma proteins
    • Symptoms: hives, itching, and flushing
    • Treatment: antihistamines and supportive care
  • Acute Hemolytic Transfusion Reaction
    • Caused by ABO incompatibility between donor and recipient blood
    • Symptoms: fever, chills, nausea, and pain
    • Treatment: supportive care and possible dialysis

Delayed Transfusion Reactions

  • Delayed Hemolytic Transfusion Reaction
    • Caused by anamnestic response to previously sensitized recipient
    • Symptoms: gradual decrease in hemoglobin and hematocrit
    • Treatment: supportive care and possible transfusion of compatible blood
  • Post-Transfusion Purpura (PTP)
    • Caused by anti-platelet antibodies in the transfused blood
    • Symptoms: thrombocytopenia and bleeding
    • Treatment: platelet transfusions and immunoglobulin therapy
  • Transfusion-Associated Graft-Versus-Host Disease (TA-GVHD)
    • Caused by engraftment of donor T-lymphocytes
    • Symptoms: fever, rash, and bone marrow suppression
    • Treatment: supportive care and possible antithymocyte globulin therapy

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Description

Learn about the different types of transfusion reactions, including acute and delayed reactions, their causes, symptoms, and treatments. Understand the immune responses involved and how to manage these reactions.

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