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Questions and Answers
Which components are involved in the activation by IFN-g?
Which components are involved in the activation by IFN-g?
- Jak1/Jak2/Tyk2 & STAT1 (correct)
- Jak1/Jak3 & STAT6
- RelA-p50 & IKKB
- Jak2/Tyk2 & STAT4
What is the important player in immune responses, including inflammation, activation, and cell survival?
What is the important player in immune responses, including inflammation, activation, and cell survival?
- TGFβRI
- STAT6
- Jak3
- NF-κB (correct)
What is the unique ubiquitin E3 ligase involved in the activation of NF-κB?
What is the unique ubiquitin E3 ligase involved in the activation of NF-κB?
- Jak2
- Tyk2
- Ubiq(TRAFs) (correct)
- Jak1
What does the canonical NF-κB pathway involve for DNA binding and activation domain?
What does the canonical NF-κB pathway involve for DNA binding and activation domain?
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After binding to the TGβRII receptor, what does the processed TGF-β dimer associate with and phosphorylate?
After binding to the TGβRII receptor, what does the processed TGF-β dimer associate with and phosphorylate?
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What does catalytically active TGFβRI phosphorylate in the TGF-β signaling pathway?
What does catalytically active TGFβRI phosphorylate in the TGF-β signaling pathway?
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What does the SMAD heterodimer induce after entering the nucleus in the TGF-β signaling pathway?
What does the SMAD heterodimer induce after entering the nucleus in the TGF-β signaling pathway?
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