7 Questions
Which components are involved in the activation by IFN-g?
Jak1/Jak2/Tyk2 & STAT1
What is the important player in immune responses, including inflammation, activation, and cell survival?
NF-κB
What is the unique ubiquitin E3 ligase involved in the activation of NF-κB?
Ubiq(TRAFs)
What does the canonical NF-κB pathway involve for DNA binding and activation domain?
RelA-p50
After binding to the TGβRII receptor, what does the processed TGF-β dimer associate with and phosphorylate?
TGFβRI
What does catalytically active TGFβRI phosphorylate in the TGF-β signaling pathway?
R-SMAD
What does the SMAD heterodimer induce after entering the nucleus in the TGF-β signaling pathway?
Transcription of target genes
This quiz covers the increased transcription of genes through the translocation of transcription factors, focusing on the role of NFAT genes in enhancing transcription of IL-2, IL-4, and TNF. It also explores the mode of action of cyclosporin and FK-506, as well as the activation process of T cells and translocation of NFAT to the nucleus.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
