Transcription Factors: Activators and Repressors

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What is the role of positive regulators in transcription?

Increase stability of RNA pol to promoter and allow more effective binding

How do negative regulators affect transcription?

Physically alter the ability of RNA pol to bind to promoter

What characteristic pattern of growth did Jacob and Monod observe when E. Coli was grown in the presence of lactose and glucose?

Diauxic growth pattern

What enzyme is required for the catabolism of lactose?

$eta$-galactosidase

During which phase of growth does glucose get used while lactose is not used at all?

First logarithmic phase (phase 1)

Test your knowledge of transcription factors, including activators and repressors, and their roles in gene expression regulation. Understand how transcription factors interact with RNA polymerase to influence the likelihood of transcription occurring.

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