Transcapillary Exchange

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Questions and Answers

Which substance has the highest permeability across the capillary membrane?

  • Urea
  • Glucose
  • Water (correct)
  • NaCl

Which substance has the lowest permeability across the capillary membrane?

  • Myoglobin
  • Albumin (correct)
  • Hemoglobin
  • Inulin

Which type of molecules can diffuse directly through the endothelial cell membrane?

  • Macromolecules
  • Non-lipid soluble substances
  • Water-soluble substances
  • Lipid-soluble substances (correct)

How do water-soluble and non-lipid soluble substances move across the capillary membrane?

<p>Through pores (C)</p> Signup and view all the answers

What is the ultrafiltrate of plasma called?

<p>Interstitial fluid (B)</p> Signup and view all the answers

What do lymphatic capillaries do?

<p>Drain excess fluid from the interstitial compartment (B)</p> Signup and view all the answers

What is the formula for fluid filtration across the capillaries according to Starling's relationship?

<p>Jv,c = (PC - PIF) - (πc - πIF) (D)</p> Signup and view all the answers

What does the osmotic reflection coefficient (σ) represent?

<p>The probability that a molecule will cross the barrier (C)</p> Signup and view all the answers

What does a σ value of 0 indicate?

<p>The membrane is freely permeable to the solute (D)</p> Signup and view all the answers

What does a σ value of 1 indicate?

<p>The molecule is impermeable to the solute (D)</p> Signup and view all the answers

Which of the following factors influence transcapillary exchange of fluid?

<p>Permeability, hydrostatic pressure, and oncotic pressure (A)</p> Signup and view all the answers

What is the net filtration pressure at the arterial end of a capillary?

<p>Hydrostatic pressure plus oncotic pressure (A)</p> Signup and view all the answers

What is the net filtration pressure at the venous end of a capillary?

<p>Oncotic pressure minus hydrostatic pressure (D)</p> Signup and view all the answers

How does net filtration pressure affect the direction of fluid movement across the capillary?

<p>It determines the direction of fluid movement (C)</p> Signup and view all the answers

How is transcapillary macromolecular exchange related to molecular size and capillary permeability?

<p>Smaller molecules have higher permeability (A)</p> Signup and view all the answers

How is capillary structure related to the osmotic reflection coefficient?

<p>Capillary structure determines the osmotic reflection coefficient (D)</p> Signup and view all the answers

What factors govern transcapillary exchange according to the Starling Relationship?

<p>Permeability, hydrostatic pressure, and oncotic pressure (D)</p> Signup and view all the answers

How can the Starling Relation be applied to different physiological perturbations?

<p>By adjusting both hydrostatic and oncotic pressures (A)</p> Signup and view all the answers

How can endogenous compound release alter capillary permeability?

<p>By increasing capillary permeability (D)</p> Signup and view all the answers

Why does normal net capillary filtration not result in edema?

<p>Because lymph flow prevents fluid accumulation (A)</p> Signup and view all the answers

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