Transcapillary Exchange
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Questions and Answers

Which substance has the highest permeability across the capillary membrane?

  • Urea
  • Glucose
  • Water (correct)
  • NaCl
  • Which substance has the lowest permeability across the capillary membrane?

  • Myoglobin
  • Albumin (correct)
  • Hemoglobin
  • Inulin
  • Which type of molecules can diffuse directly through the endothelial cell membrane?

  • Macromolecules
  • Non-lipid soluble substances
  • Water-soluble substances
  • Lipid-soluble substances (correct)
  • How do water-soluble and non-lipid soluble substances move across the capillary membrane?

    <p>Through pores</p> Signup and view all the answers

    What is the ultrafiltrate of plasma called?

    <p>Interstitial fluid</p> Signup and view all the answers

    What do lymphatic capillaries do?

    <p>Drain excess fluid from the interstitial compartment</p> Signup and view all the answers

    What is the formula for fluid filtration across the capillaries according to Starling's relationship?

    <p>Jv,c = (PC - PIF) - (πc - πIF)</p> Signup and view all the answers

    What does the osmotic reflection coefficient (σ) represent?

    <p>The probability that a molecule will cross the barrier</p> Signup and view all the answers

    What does a σ value of 0 indicate?

    <p>The membrane is freely permeable to the solute</p> Signup and view all the answers

    What does a σ value of 1 indicate?

    <p>The molecule is impermeable to the solute</p> Signup and view all the answers

    Which of the following factors influence transcapillary exchange of fluid?

    <p>Permeability, hydrostatic pressure, and oncotic pressure</p> Signup and view all the answers

    What is the net filtration pressure at the arterial end of a capillary?

    <p>Hydrostatic pressure plus oncotic pressure</p> Signup and view all the answers

    What is the net filtration pressure at the venous end of a capillary?

    <p>Oncotic pressure minus hydrostatic pressure</p> Signup and view all the answers

    How does net filtration pressure affect the direction of fluid movement across the capillary?

    <p>It determines the direction of fluid movement</p> Signup and view all the answers

    How is transcapillary macromolecular exchange related to molecular size and capillary permeability?

    <p>Smaller molecules have higher permeability</p> Signup and view all the answers

    How is capillary structure related to the osmotic reflection coefficient?

    <p>Capillary structure determines the osmotic reflection coefficient</p> Signup and view all the answers

    What factors govern transcapillary exchange according to the Starling Relationship?

    <p>Permeability, hydrostatic pressure, and oncotic pressure</p> Signup and view all the answers

    How can the Starling Relation be applied to different physiological perturbations?

    <p>By adjusting both hydrostatic and oncotic pressures</p> Signup and view all the answers

    How can endogenous compound release alter capillary permeability?

    <p>By increasing capillary permeability</p> Signup and view all the answers

    Why does normal net capillary filtration not result in edema?

    <p>Because lymph flow prevents fluid accumulation</p> Signup and view all the answers

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