20 Questions
Which substance has the highest permeability across the capillary membrane?
Water
Which substance has the lowest permeability across the capillary membrane?
Albumin
Which type of molecules can diffuse directly through the endothelial cell membrane?
Lipid-soluble substances
How do water-soluble and non-lipid soluble substances move across the capillary membrane?
Through pores
What is the ultrafiltrate of plasma called?
Interstitial fluid
What do lymphatic capillaries do?
Drain excess fluid from the interstitial compartment
What is the formula for fluid filtration across the capillaries according to Starling's relationship?
Jv,c = (PC - PIF) - (πc - πIF)
What does the osmotic reflection coefficient (σ) represent?
The probability that a molecule will cross the barrier
What does a σ value of 0 indicate?
The membrane is freely permeable to the solute
What does a σ value of 1 indicate?
The molecule is impermeable to the solute
Which of the following factors influence transcapillary exchange of fluid?
Permeability, hydrostatic pressure, and oncotic pressure
What is the net filtration pressure at the arterial end of a capillary?
Hydrostatic pressure plus oncotic pressure
What is the net filtration pressure at the venous end of a capillary?
Oncotic pressure minus hydrostatic pressure
How does net filtration pressure affect the direction of fluid movement across the capillary?
It determines the direction of fluid movement
How is transcapillary macromolecular exchange related to molecular size and capillary permeability?
Smaller molecules have higher permeability
How is capillary structure related to the osmotic reflection coefficient?
Capillary structure determines the osmotic reflection coefficient
What factors govern transcapillary exchange according to the Starling Relationship?
Permeability, hydrostatic pressure, and oncotic pressure
How can the Starling Relation be applied to different physiological perturbations?
By adjusting both hydrostatic and oncotic pressures
How can endogenous compound release alter capillary permeability?
By increasing capillary permeability
Why does normal net capillary filtration not result in edema?
Because lymph flow prevents fluid accumulation
Test your knowledge on transcapillary exchange and the factors that influence it. This quiz covers topics such as permeability, hydrostatic pressure, and oncotic pressure and their roles in fluid exchange across capillaries.
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