Podcast
Questions and Answers
Which trial formed the basis for the original 3-hour time window for tPA administration?
Which trial formed the basis for the original 3-hour time window for tPA administration?
- NINDS trial (correct)
- National Institute of Neurological Disorders and Stroke
- European Cooperative Acute Stroke Study (ECASS) I
- Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke
What is the maximum time window for tPA administration in a select group of patients?
What is the maximum time window for tPA administration in a select group of patients?
- 4 hours
- 3 hours
- 4.5 hours (correct)
- 2 hours
What is the absolute risk increase in symptomatic intracerebral hemorrhage (ICH) with IV tPA within 3 hours of symptom onset?
What is the absolute risk increase in symptomatic intracerebral hemorrhage (ICH) with IV tPA within 3 hours of symptom onset?
- 7%
- 8%
- 9%
- 6% (correct)
What is the number needed to treat to achieve good recovery in one patient who would have otherwise had a poor outcome with tPA administration within 3 hours of symptom onset?
What is the number needed to treat to achieve good recovery in one patient who would have otherwise had a poor outcome with tPA administration within 3 hours of symptom onset?
What did the pooled analysis of the Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke, European Cooperative Acute Stroke Study (ECASS) I and II, and NINDS trials show?
What did the pooled analysis of the Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke, European Cooperative Acute Stroke Study (ECASS) I and II, and NINDS trials show?