Questions and Answers
Which of the following is NOT considered a relative contraindication for IV tPA treatment in patients with minor or resolving deficits?
Seizures
What is the main concern when considering IV tPA treatment for patients with seizure at time of presentation?
Treating a stroke mimic
Why should blood glucose be measured and corrected in all patients?
To prevent neurologic deficits
What did a subanalysis of the NINDS trial confirm about IV tPA treatment in patients with minor or resolving deficits?
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Study Notes
IV tPA Treatment Contraindications and Considerations
- Relative contraindications for IV tPA treatment in patients with minor or resolving deficits include advanced age, history of stroke or transient ischemic attack, diabetes, and hypertension, but NOT isolated aphasia.
- The main concern when considering IV tPA treatment for patients with seizure at time of presentation is post-ictal hemorrhage.
- Blood glucose should be measured and corrected in all patients to prevent exacerbation of ischemic injury.
- A subanalysis of the NINDS trial confirmed that IV tPA treatment in patients with minor or resolving deficits is safe and effective.
