Podcast
Questions and Answers
Which of the following is NOT considered a relative contraindication for IV tPA treatment in patients with minor or resolving deficits?
Which of the following is NOT considered a relative contraindication for IV tPA treatment in patients with minor or resolving deficits?
- Seizures (correct)
- Rapidly resolving deficit
- Hypo- or hyperglycemia
- Minor symptoms
What is the main concern when considering IV tPA treatment for patients with seizure at time of presentation?
What is the main concern when considering IV tPA treatment for patients with seizure at time of presentation?
- Treating a stroke mimic (correct)
- Risk of hemorrhagic conversion
- Onset seizures
- Rate of hemorrhagic complications
Why should blood glucose be measured and corrected in all patients?
Why should blood glucose be measured and corrected in all patients?
- To prevent neurologic deficits (correct)
- To treat a stroke mimic
- To mimic acute stroke
- To increase the risk of hemorrhagic conversion
What did a subanalysis of the NINDS trial confirm about IV tPA treatment in patients with minor or resolving deficits?
What did a subanalysis of the NINDS trial confirm about IV tPA treatment in patients with minor or resolving deficits?
Study Notes
IV tPA Treatment Contraindications and Considerations
- Relative contraindications for IV tPA treatment in patients with minor or resolving deficits include advanced age, history of stroke or transient ischemic attack, diabetes, and hypertension, but NOT isolated aphasia.
- The main concern when considering IV tPA treatment for patients with seizure at time of presentation is post-ictal hemorrhage.
- Blood glucose should be measured and corrected in all patients to prevent exacerbation of ischemic injury.
- A subanalysis of the NINDS trial confirmed that IV tPA treatment in patients with minor or resolving deficits is safe and effective.
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Description
Identify Relative Contraindications for IV tPA Treatment