15 Questions
Which method is used to increase the excretion of drugs/metabolites through the kidney?
Diuretics
Which substances help in promoting the excretion of weak acids by increasing their ionization in the renal tubules?
Na bicarbonate & acetazolamide
Which method is not effective for chemicals that are reabsorbed by renal tubules due to their low concentration in the urine?
Diuretics
Which substances can be used to alkalinize the urine and promote the excretion of weak acidic drugs?
Na bicarbonate & acetazolamide
Which method promotes the excretion of weak bases by increasing their ionization in the renal tubules?
Ammonium chloride & ascorbic acid
What is the primary reason to enhance the elimination of a toxic agent from the circulation?
To minimize the distribution of the toxic agent in body compartments
Which type of chemicals may not be effectively eliminated through forced diuresis?
Chemicals that are not reabsorbed by renal tubules
Which substances can be used to promote the excretion of weak acidic drugs by increasing their ionization in the renal tubules?
Na bicarbonate & acetazolamide
Which method promotes the excretion of weak bases by increasing their ionization in the renal tubules?
Acidification of urine
What is the primary purpose of using diuretics to increase urine output in toxicology?
To enhance the excretion of drugs/metabolites through the kidney
In toxicology, which method promotes the excretion of weak acids by increasing their ionization in the renal tubules?
Alkalinization of urine
What is the primary purpose of using diuretics to increase urine output in toxicology?
Increasing excretion of drugs/metabolites
Which substances can be used to promote the excretion of weak acidic drugs by increasing their ionization in the renal tubules?
Sodium bicarbonate & acetazolamide
Which method is used to increase the excretion of drugs/metabolites through the kidney?
Forced diuresis
What type of chemicals may not be effectively eliminated through forced diuresis?
Weak bases
Test your knowledge of enhancing elimination of toxins in toxicology. Learn about factors that influence the need for enhancing toxin elimination from the body.
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