15 Questions
Which method can be used to enhance the excretion of weak acids through the kidney?
Alkalinization of urine
What is the primary purpose of using diuretics in enhancing elimination of toxins?
To increase the urine output
Which substance is used to alkalinize the urine for promoting the excretion of weak acidic drugs?
Na bicarbonate
Why isn't forced diuresis effective for chemicals that are reabsorbed by renal tubules?
Because the concentration of these chemicals in the urine is low
Which action promotes the excretion of weak bases through the kidney by increasing their ionization?
Acidification of urine
What is the primary consideration for enhancing elimination of a poison from the circulation?
High concentration in plasma relative to its concentration in other body compartments
Which method promotes the excretion of weak bases through the kidney by increasing their ionization?
Acidification of urine
What is the effect of alkalinizing the urine for promoting the excretion of weak acidic drugs?
Promotes ion trapping in renal tubules
Why isn't forced diuresis effective for chemicals that are reabsorbed by renal tubules?
Reabsorption by renal tubules
Which action is used to increase the urine output for enhancing elimination of toxins?
Forced diuresis with diuretics
What is the main consideration for enhancing elimination of a poison from the circulation?
High concentration in plasma relative to other body compartments
Which method can be used to enhance the excretion of weak acids through the kidney?
Alkalinization of urine
Why isn't forced diuresis effective for chemicals that are reabsorbed by renal tubules?
Low concentration of these chemicals in the urine
Which action promotes the excretion of weak bases through the kidney by increasing their ionization?
Acidification of urine
What is the effect of alkalinizing the urine for promoting the excretion of weak acidic drugs?
Increases their ionization and promotes ion trapping in the renal tubules
This quiz explores the methods to enhance elimination of toxic agents from the body. It covers the conditions under which enhancing elimination is beneficial and the characteristics of toxins that make them suitable for enhanced elimination.
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