Top 300 Drugs: Classification & Mechanism of Action
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Questions and Answers

What is Acyclovir classified as?

  • Antiviral (correct)
  • Antibiotic
  • Antiparasitic
  • Antifungal
  • What is the action of Adalimumab?

    It inhibits TNFα by binding to it and preventing its interaction with TNF receptors.

    What type of drug is Albuterol?

    Beta2-agonist

    What is the classification of Albuterol-ipratropium?

    <p>Combination beta2-agonist and anticholinergic</p> Signup and view all the answers

    What is the mechanism of action of Alendronate?

    <p>It inhibits osteoclast-mediated bone resorption.</p> Signup and view all the answers

    What does Allopurinol inhibit?

    <p>Xanthine oxidase</p> Signup and view all the answers

    What type of medication is Alprazolam?

    <p>Benzodiazepine</p> Signup and view all the answers

    What class of drug is Amiodarone?

    <p>Antiarrhythmic (Class III)</p> Signup and view all the answers

    What is the primary action of Amitriptyline?

    <p>It increases synaptic concentration of serotonin and norepinephrine.</p> Signup and view all the answers

    What type of drug is Amlodipine?

    <p>Calcium channel blocker</p> Signup and view all the answers

    What is the combination of Amlodipine-benazepril?

    <p>Calcium channel blocker and ACE inhibitor</p> Signup and view all the answers

    What does Amoxicillin inhibit?

    <p>Bacterial cell wall synthesis</p> Signup and view all the answers

    What is unique about Amoxicillin-clavulanate?

    <p>It inactivates beta-lactamase enzymes.</p> Signup and view all the answers

    What class of drug is Amphetamine-dextroamphetamine?

    <p>CNS stimulant</p> Signup and view all the answers

    What does Anastrozole inhibit?

    <p>Conversion of androgens to estrogens</p> Signup and view all the answers

    What is the action of Apixaban?

    <p>It inhibits factor Xa.</p> Signup and view all the answers

    What type of drug is Aripiprazole?

    <p>Antipsychotic</p> Signup and view all the answers

    What is the mechanism of action of Aspirin-dipyridamole?

    <p>It inhibits platelet aggregation.</p> Signup and view all the answers

    What is Atenolol classified as?

    <p>Beta1-selective blocker</p> Signup and view all the answers

    Study Notes

    Antiviral and Inflammatory Drugs

    • Acyclovir (Zovirax, Sitavig, Avaclyr): Antiviral drug that converts to an active triphosphate form, blocking viral DNA polymerase and inhibiting viral DNA replication.
    • Adalimumab (Humira): TNFα inhibitor that binds to TNFα, preventing interaction with cell surface receptors, thereby reducing cytokine-driven inflammation.

    Respiratory Medications

    • Albuterol (ProAir, Ventolin, Proventil): Beta2-agonist that relaxes bronchial smooth muscle by stimulating beta-2 adrenergic receptors.
    • Albuterol-ipratropium (Combivent Respimat, DuoNeb): Combines beta2-agonist and anticholinergic effects to induce bronchodilation through both receptor activation and blockade of acetylcholine action.

    Bone Health and Gout Treatment

    • Alendronate (Fosamax, Binosto): Bisphosphonate that inhibits osteoclast activity, reducing bone resorption.
    • Allopurinol (Zyloprim, Aloprim): Xanthine oxidase inhibitor that lowers uric acid production by inhibiting xanthine oxidase.

    CNS Acting Drugs

    • Alprazolam (Xanax): Benzodiazepine that enhances CNS depression through GABA receptor potentiation.
    • Amitriptyline (Elavil): Tricyclic antidepressant that increases concentrations of serotonin and norepinephrine by inhibiting their reuptake.
    • Amphetamine-dextroamphetamine (Adderall, Mydayis): CNS stimulant that blocks the reuptake of norepinephrine and dopamine, enhancing their release.

    Cardiovascular Medications

    • Amiodarone (Cordarone, Pacerone): Class III antiarrhythmic that primarily blocks potassium channels, prolonging action potential and refractory periods.
    • Amlodipine (Norvasc, Katerzia): Dihydropyridine calcium channel blocker that decreases peripheral vascular resistance by inhibiting calcium influx in vascular smooth muscle.
    • Amlodipine-benazepril (Lotrel): Combination drug that functions as both a calcium channel blocker and an ACE inhibitor, promoting vasodilation and preventing angiotensin II formation.

    Antibiotics

    • Amoxicillin (Amoxil, Trimox, Moxatag): Penicillin antibiotic that interferes with bacterial cell wall synthesis via binding to penicillin-binding proteins.
    • Amoxicillin-clavulanate (Augmentin): Similar to amoxicillin but includes clavulanate to inactivate beta-lactamase enzymes, enhancing its effectiveness against resistant bacteria.

    Hormonal and Coagulation Factors

    • Anastrozole (Arimidex): Aromatase inhibitor that blocks androgen to estrogen conversion in peripheral tissues, used in breast cancer treatment.
    • Apixaban (Eliquis): Factor Xa inhibitor that reduces thrombin generation and thrombus formation through reversible active site inhibition.

    Antipsychotics and Antiplatelet Agents

    • Aripiprazole (Abilify): Antipsychotic that acts as a partial agonist at dopamine D2 and serotonin 5-HT1a receptors while antagonizing 5-HT2a receptors.
    • Aspirin-dipyridamole (Aggrenox): Antiplatelet agent that irreversibly inhibits platelet cyclooxygenase to prevent thromboxane A2 production, and increases cAMP levels to reduce platelet aggregation.

    Adrenergic Blockers

    • Atenolol (Tenormin): Beta1-selective blocker that targets beta1-adrenergic receptors to decrease heart rate and contractility, utilized in hypertension and cardiac issues.

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    Description

    This quiz focuses on the classification and mechanisms of action of the top 300 drugs. Each card provides a drug name along with its function, supporting you in comprehending complex pharmacological concepts. Perfect for medical students and professionals looking to enhance their drug knowledge.

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