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What is the reason for neonates and infants with TDT or SCD being asymptomatic while their fetal hemoglobin levels remain high?

  • The production of fetal hemoglobin is developmentally regulated (correct)
  • The synthesis of fetal hemoglobin increases postnatally
  • The level of γ-globin decreases postnatally
  • The production of β-globin and adult hemoglobin decreases postnatally

    • What is the significance of elevated levels of fetal hemoglobin in patients with TDT and SCD?

  • They are associated with improved morbidity and mortality (correct)
  • They cause symptomatic disease in patients
  • They decrease postnatally in patients
  • They have no effect on the health of patients

    • What is the consequence of co-inheriting hereditary persistence of fetal hemoglobin in patients with TDT or SCD?

  • They have little or no disease (correct)
  • They have increased levels of adult hemoglobin
  • They have decreased levels of fetal hemoglobin
  • They have increased morbidity and mortality

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