Tissue Thromboplastin Contamination in Coagulation Tests

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What can tissue thromboplastin do to coagulation tests?

Compromise the results of other coagulation tests

When is tissue thromboplastin no longer considered a clinically significant problem?

Unless the draw is difficult and involves a lot of needle manipulation

What is the recommended action if a coagulation test other than PT/INR or PTT/aPTT is the first or only tube collected?

Draw a few milliliters of blood into a nonadditive tube before it is collected

What is the purpose of a clear or discard tube in the context of blood collection?

To remove tissue fluid from the needle and then thrown away

What should be done if there is no documented evidence to show that a specific coagulation test is unaffected by tissue thromboplastin?

Draw blood into a nonadditive tube before collecting the sample

Test your knowledge on tissue thromboplastin contamination and its interference with coagulation tests. Learn about its presence in tissue fluid and its impact on prothrombin time (PT/INR) and partial thromboplastin time (PTT) tests.

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