Tissue Repair and Healing Processes

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Questions and Answers

What characterizes repair as opposed to regeneration in tissue healing?

  • Involves the reformation of all types of tissues
  • Replacement by connective tissue, leading to scarring (correct)
  • Restoration of original tissue architecture and function
  • Occurs only in the liver

Which of the following is NOT a cause of acute localized venous congestion?

  • Strangulation
  • Twisting of the pedicle
  • Inflammation (correct)
  • Thrombosis

Which statement accurately describes exudate compared to transudate?

  • Exudate has low protein content and clots on standing
  • Transudate has no inflammatory cells and is caused by injury
  • Transudate occurs due to inflammation and has a high protein content
  • Exudate contains inflammatory cells and is caused by inflammation (correct)

What is the primary difference between first intention and second intention healing?

<p>First intention requires less time for healing than second intention (D)</p> Signup and view all the answers

Which type of edema is specifically associated with right side heart failure?

<p>Cardiac edema (B)</p> Signup and view all the answers

Which characteristic does NOT pertain to benign tumors?

<p>Fast-growing (C)</p> Signup and view all the answers

What is an example of dystrophic calcification?

<p>Calcium deposits in dead tissues such as damaged heart valves (B)</p> Signup and view all the answers

What are the two classifications of edema based on site?

<p>Localized and generalized (D)</p> Signup and view all the answers

Which statement accurately distinguishes metastatic calcification from dystrophic calcification?

<p>Dystrophic calcification occurs in dead tissues, while metastatic calcification occurs in normal tissues (D)</p> Signup and view all the answers

Which feature is NOT indicative of malignant tumors?

<p>Small size (D)</p> Signup and view all the answers

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Study Notes

Repair vs. Regeneration

  • Regeneration restores original tissue architecture and function after injury.
  • Repair replaces damaged tissue with connective tissue (scarring), altering both structure and function.

Acute Localized Venous Congestion

  • Causes: Thrombosis, ligature, strangulation, or twisting of the pedicle.
  • Effects:
    • Rapid and severe distention of veins.
    • Edema develops quickly in the tissues.
    • In the intestine, infarction and gangrene may occur.

Exudate vs. Transudate

  • Exudate:
    • Present in inflammation.
    • High protein content.
    • Clots on standing due to fibrinogen.
    • Contains inflammatory cells.
  • Transudate:
    • Occurs due to conditions other than inflammation.
    • Low protein content.
    • Does not clot on standing due to lack of fibrinogen.
    • Lacks inflammatory cells.

Types of Healing

  • First Intention Healing: Occurs in wounds with clean opposing edges, like surgical incisions.
  • Second Intention Healing: Occurs in wounds with separated edges, requiring more tissue for closure.

Classification of Edema

  • According to site:
    • Localized Edema: Swelling in a specific area.
    • Generalized Edema: Swelling throughout the body.
  • According to consistency:
    • Pitting Edema: Soft edema that leaves an indentation when pressed.
    • Non-Pitting Edema: Hard edema that does not indent with pressure.

Cardiac Edema

  • Generalized edema caused by right-sided heart failure.

Benign vs. Malignant Tumors

  • Benign Tumors:
    • Small, slow-growing.
    • Non-invasive.
    • Well-differentiated.
    • Stay localized.
    • Cannot invade or metastasize.
  • Malignant Tumors:
    • Large, fast-growing.
    • Invasive.
    • Poorly-differentiated.
    • Metastasize to other parts of the body.
    • Infiltrate, invade, and destroy surrounding tissues.

Dystrophic vs. Metastatic Calcification

  • Dystrophic Calcification: Deposition of calcium in dead tissues.
    • Example: Damaged heart valves.
  • Metastatic Calcification: Deposition of calcium salts in normal tissues.
    • Example: Vitamin D intoxication.

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