Tissue Regeneration vs. Repair

The ability of a tissue to restore its normal structure and function after injury.

The process of replacing damaged tissue with the same type of cells, restoring normal function.

The process of replacing damaged tissue with scar tissue, composed mainly of collagen fibers. This results in a loss of normal function.

Specialized cells that can divide and differentiate to produce various cell types within a tissue.

The formation of new blood vessels, essential for providing nutrients and oxygen to healing tissues.

Labile tissues are constantly being renewed by cell division. They are easily regenerated.

Stable tissues can divide after injury but are not constantly renewing like labile tissues.

The deposition of collagen and other extracellular matrix components, forming a scar tissue. This is typical for tissues unable to fully regenerate.

Cardiac muscle cells and most neurons.

The process of replacing damaged tissue with scar tissue, mainly composed of collagen fibers. It's essential for wound closure and tissue repair, but it can lead to loss of normal function.

The initial stage of tissue repair, characterized by the formation of a blood clot.

The second phase of tissue repair, marked by the recruitment of immune cells to the site of injury to clear debris and pathogens.

Specialized cells found within tissues that can divide and differentiate to produce various cell types, crucial for tissue regeneration.

The fibrous connective tissue that forms during the healing process, containing newly formed blood vessels and fibroblasts, ultimately leading to scar formation.

The liver's exceptional ability to regenerate after injury, involving both the proliferation of remaining hepatocytes and repopulation from liver progenitor cells.

The process of removing damaged tissue, bacteria, and foreign bodies from a wound. It's like a cleaning crew preparing a site for construction.

The process of collagen fibers being laid down by fibroblasts, forming a strong, flexible tissue that replaces damaged tissue.

The process of cells dividing and multiplying to replace lost or damaged cells in a wound.

A cell type crucial for wound healing, they produce collagen fibers and help to close wounds.

A protein that stimulates fibroblast activity, promoting collagen deposition and wound closure. It's like a 'build' signal for fibroblasts.

A type of fibroblast that exhibits smooth muscle-like properties, playing a role in scar contraction. It's like a mini-muscle in the scar.

The deposition of connective tissue, primarily collagen, that helps build scar tissue. It's the structural foundation of a scar.

The process of reducing the blood supply to a healing wound as scar tissue matures. The scar becomes less red and more pale.

A process where the body strengthens and shrinks the wound by replacing unorganized collagen with organized collagen and by degrading collagen. It starts 21 days after injury and can continue for over a year.

A family of enzymes responsible for breaking down collagen and other components of the extracellular matrix during wound remodeling.

The type of collagen found in newly formed granulation tissue, initially more flexible

The type of collagen found in mature scars and normal tissues, more robust and organized