Tissue Engineering Scaffolds

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What is the ultimate goal of cells growing and interacting with each other in a scaffold?

To form a fully functional tissue (correct)

To create a hybrid biomaterial

To induce an immune response

To synthesize new polymers

What is a key difference between natural and synthetic polymers used in scaffolds?

Synthetic polymers are more reproducible but less bioactive (correct)

Natural polymers are more toxic

Natural polymers are more versatile

Synthetic polymers are more biocompatible

When choosing a 3D culture system, what factor determines the most effective scaffold and system?

Scaffold material properties

Incubation temperature

Culture medium composition

Cell type and phenotype (correct)

What should a scaffold material ensure to facilitate cell growth and interaction?

Be non-toxic and allow normal cell behavior Signup and view all the answers

What is a characteristic of natural polymers used in scaffolds?

Biocompatibility and low toxicity Signup and view all the answers

Why is biodegradability an important property of scaffolds?

To allow for tissue remodeling and regeneration Signup and view all the answers

What is a crucial property of a material for tissue engineering?

Being amenable to in vivo degradation Signup and view all the answers

What is the primary purpose of a filter well insert in tissue engineering?

To allow for the study of cell interaction and tissue modeling Signup and view all the answers

What is a key consideration at the molecular level for scaffold architecture?

The pore size and pore structure of the material Signup and view all the answers

What is an example of a biodegradable material used in tissue engineering?

Bioglass or Bioceramic Scaffolds Signup and view all the answers

What is a benefit of using filter well inserts in tissue engineering?

They provide ready access to medium and gas exchange Signup and view all the answers

What is a key characteristic of a material's physicochemical properties in tissue engineering?

Its elasticity or stiffness Signup and view all the answers

What is a characteristic of metallic scaffolds?

High compressive strength and excellent fatigue resistance Signup and view all the answers

What is a common material used in non-gel polymer scaffolds?

Collagen Signup and view all the answers

What is a characteristic of biodegradable synthetic polymers?

Breakdown by physiological processes Signup and view all the answers

What is a composite scaffold made of?

Two or more distinctly different materials Signup and view all the answers

What is the purpose of embedment in Matrigel in organoid culture?

To enhance tissue expansion and neuroepithelium formation Signup and view all the answers

What is the result of the procedure to generate cerebral organoids?

Formation of cerebral tissue Signup and view all the answers