Tissue Engineering Scaffolds
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Questions and Answers

What is the ultimate goal of cells growing and interacting with each other in a scaffold?

  • To form a fully functional tissue (correct)
  • To create a hybrid biomaterial
  • To induce an immune response
  • To synthesize new polymers
  • What is a key difference between natural and synthetic polymers used in scaffolds?

  • Synthetic polymers are more reproducible but less bioactive (correct)
  • Natural polymers are more toxic
  • Natural polymers are more versatile
  • Synthetic polymers are more biocompatible
  • When choosing a 3D culture system, what factor determines the most effective scaffold and system?

  • Scaffold material properties
  • Incubation temperature
  • Culture medium composition
  • Cell type and phenotype (correct)
  • What should a scaffold material ensure to facilitate cell growth and interaction?

    <p>Be non-toxic and allow normal cell behavior</p> Signup and view all the answers

    What is a characteristic of natural polymers used in scaffolds?

    <p>Biocompatibility and low toxicity</p> Signup and view all the answers

    Why is biodegradability an important property of scaffolds?

    <p>To allow for tissue remodeling and regeneration</p> Signup and view all the answers

    What is a crucial property of a material for tissue engineering?

    <p>Being amenable to in vivo degradation</p> Signup and view all the answers

    What is the primary purpose of a filter well insert in tissue engineering?

    <p>To allow for the study of cell interaction and tissue modeling</p> Signup and view all the answers

    What is a key consideration at the molecular level for scaffold architecture?

    <p>The pore size and pore structure of the material</p> Signup and view all the answers

    What is an example of a biodegradable material used in tissue engineering?

    <p>Bioglass or Bioceramic Scaffolds</p> Signup and view all the answers

    What is a benefit of using filter well inserts in tissue engineering?

    <p>They provide ready access to medium and gas exchange</p> Signup and view all the answers

    What is a key characteristic of a material's physicochemical properties in tissue engineering?

    <p>Its elasticity or stiffness</p> Signup and view all the answers

    What is a characteristic of metallic scaffolds?

    <p>High compressive strength and excellent fatigue resistance</p> Signup and view all the answers

    What is a common material used in non-gel polymer scaffolds?

    <p>Collagen</p> Signup and view all the answers

    What is a characteristic of biodegradable synthetic polymers?

    <p>Breakdown by physiological processes</p> Signup and view all the answers

    What is a composite scaffold made of?

    <p>Two or more distinctly different materials</p> Signup and view all the answers

    What is the purpose of embedment in Matrigel in organoid culture?

    <p>To enhance tissue expansion and neuroepithelium formation</p> Signup and view all the answers

    What is the result of the procedure to generate cerebral organoids?

    <p>Formation of cerebral tissue</p> Signup and view all the answers

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