Tissue Engineering Scaffolds

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Questions and Answers

What is the ultimate goal of cells growing and interacting with each other in a scaffold?

  • To form a fully functional tissue (correct)
  • To create a hybrid biomaterial
  • To induce an immune response
  • To synthesize new polymers

What is a key difference between natural and synthetic polymers used in scaffolds?

  • Synthetic polymers are more reproducible but less bioactive (correct)
  • Natural polymers are more toxic
  • Natural polymers are more versatile
  • Synthetic polymers are more biocompatible

When choosing a 3D culture system, what factor determines the most effective scaffold and system?

  • Scaffold material properties
  • Incubation temperature
  • Culture medium composition
  • Cell type and phenotype (correct)

What should a scaffold material ensure to facilitate cell growth and interaction?

<p>Be non-toxic and allow normal cell behavior (A)</p> Signup and view all the answers

What is a characteristic of natural polymers used in scaffolds?

<p>Biocompatibility and low toxicity (C)</p> Signup and view all the answers

Why is biodegradability an important property of scaffolds?

<p>To allow for tissue remodeling and regeneration (D)</p> Signup and view all the answers

What is a crucial property of a material for tissue engineering?

<p>Being amenable to in vivo degradation (D)</p> Signup and view all the answers

What is the primary purpose of a filter well insert in tissue engineering?

<p>To allow for the study of cell interaction and tissue modeling (B)</p> Signup and view all the answers

What is a key consideration at the molecular level for scaffold architecture?

<p>The pore size and pore structure of the material (B)</p> Signup and view all the answers

What is an example of a biodegradable material used in tissue engineering?

<p>Bioglass or Bioceramic Scaffolds (D)</p> Signup and view all the answers

What is a benefit of using filter well inserts in tissue engineering?

<p>They provide ready access to medium and gas exchange (B)</p> Signup and view all the answers

What is a key characteristic of a material's physicochemical properties in tissue engineering?

<p>Its elasticity or stiffness (A)</p> Signup and view all the answers

What is a characteristic of metallic scaffolds?

<p>High compressive strength and excellent fatigue resistance (D)</p> Signup and view all the answers

What is a common material used in non-gel polymer scaffolds?

<p>Collagen (C)</p> Signup and view all the answers

What is a characteristic of biodegradable synthetic polymers?

<p>Breakdown by physiological processes (C)</p> Signup and view all the answers

What is a composite scaffold made of?

<p>Two or more distinctly different materials (C)</p> Signup and view all the answers

What is the purpose of embedment in Matrigel in organoid culture?

<p>To enhance tissue expansion and neuroepithelium formation (B)</p> Signup and view all the answers

What is the result of the procedure to generate cerebral organoids?

<p>Formation of cerebral tissue (D)</p> Signup and view all the answers

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