Thyroid Hormones and Their Functions Quiz

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Questions and Answers

What enzyme promotes the oxidation of iodine in the formation of iodine capable of combining with tyrosine?

  • Thyroid peroxidase (correct)
  • Lipase
  • Amylase
  • Insulinase

What is the process of binding iodine with the thyroglobulin molecule called?

  • Tyrosination
  • Organification (correct)
  • Iodination
  • Thyroxination

Which molecule contains up to 30 thyroxine molecules and a few triiodothyronine molecules?

  • Thyroglobulin (correct)
  • Thyroid peroxidase
  • Thyronine
  • Insulin

What is the first step in the iodization of tyrosine during the process of iodination and coupling?

<p>Monoiodotyrosine (A)</p> Signup and view all the answers

What molecule is responsible for the 'organification' of the thyroglobulin with iodine?

<p>Iodinase (D)</p> Signup and view all the answers

What substance accompanies thyroid peroxidase in promoting the oxidation of iodide ions to iodine?

<p>Hydrogen peroxide (D)</p> Signup and view all the answers

Which hormones are commonly known as T4 and T3?

<p>Triiodothyronine and thyroxine (A)</p> Signup and view all the answers

What happens to the basal metabolic rate (BMR) when there is a complete lack of thyroid secretion?

<p>It decreases to 40-50% below normal (B)</p> Signup and view all the answers

Which hormone controls thyroid secretion primarily?

<p>Thyroid-stimulating hormone (TSH) (A)</p> Signup and view all the answers

What percentage of metabolically active hormones secreted by the thyroid gland is thyroxine?

<p>93% (D)</p> Signup and view all the answers

What is the primary function of triiodothyronine (T3) and thyroxine (T4)?

<p>Increase the BMR (C)</p> Signup and view all the answers

Which hormone is also secreted by the thyroid gland apart from T3 and T4?

<p>Calcitonin (B)</p> Signup and view all the answers

What is the main effect of thyroid hormones on gene transcription?

<p>Activate transcription of large numbers of genes (C)</p> Signup and view all the answers

How does thyroid hormone affect glucose metabolism?

<p>Stimulates rapid uptake of glucose by the cells (B)</p> Signup and view all the answers

Which of the following statements about fat metabolism under thyroid hormone influence is correct?

<p>Fat metabolism is enhanced (D)</p> Signup and view all the answers

What is the result of the overall increase in cellular metabolic enzymes caused by thyroid hormone?

<p>Enhanced synthesis of structural proteins (C)</p> Signup and view all the answers

Why are thyroid hormones released slowly to tissue cells?

<p>Because of high affinity of plasma-binding proteins for thyroid hormones (C)</p> Signup and view all the answers

How does the effect of thyroid hormone on carbohydrate metabolism impact insulin secretion?

<p>Increases insulin secretion (A)</p> Signup and view all the answers

What effect does increased thyroid hormone have on the concentrations of cholesterol, phospholipids, and triglycerides in the plasma?

<p>Decreases cholesterol, phospholipids, and triglycerides (B)</p> Signup and view all the answers

What is the primary role of lipids when they are mobilized rapidly from fat tissue?

<p>Accelerate the oxidation of free fatty acids by cells (A)</p> Signup and view all the answers

How does hyperthyroidism typically affect the size of the thyroid gland in patients?

<p>Increases the size significantly (C)</p> Signup and view all the answers

Which protein has the highest binding strength for thyroxine transport in the blood?

<p>Throxine-binding globulin (TBG) (C)</p> Signup and view all the answers

What effect does increased thyroid hormone have on the size of the thyroid gland?

<p>Triples the size (A)</p> Signup and view all the answers

What physiological consequence results from the rapid mobilization of lipids from fat tissue?

<p>Accelerates the oxidation of free fatty acids by cells (B)</p> Signup and view all the answers

What is the underlying cause of hyperthyroidism in Graves' disease?

<p>Antibodies binding to thyroid cell receptors (B)</p> Signup and view all the answers

What do thyroid-stimulating immunoglobulins (TSIs) do in individuals with Graves' disease?

<p>Promote thyroid growth and hormone production (A)</p> Signup and view all the answers

How does Graves' disease affect the size of the thyroid gland?

<p>It enlarges the thyroid gland (C)</p> Signup and view all the answers

What is a common symptom associated with a goiter?

<p>Swollen neck (B)</p> Signup and view all the answers

What do radioactive iodine uptake studies indicate in hyperplastic glands?

<p>Excess thyroid hormone secretion (C)</p> Signup and view all the answers

In Graves' disease, what role do TSIs play in the production of thyroid hormones?

<p>Stimulate excess hormone production (D)</p> Signup and view all the answers

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