Thyroid Hormones and Their Functions Quiz
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Questions and Answers

What enzyme promotes the oxidation of iodine in the formation of iodine capable of combining with tyrosine?

  • Thyroid peroxidase (correct)
  • Lipase
  • Amylase
  • Insulinase
  • What is the process of binding iodine with the thyroglobulin molecule called?

  • Tyrosination
  • Organification (correct)
  • Iodination
  • Thyroxination
  • Which molecule contains up to 30 thyroxine molecules and a few triiodothyronine molecules?

  • Thyroglobulin (correct)
  • Thyroid peroxidase
  • Thyronine
  • Insulin
  • What is the first step in the iodization of tyrosine during the process of iodination and coupling?

    <p>Monoiodotyrosine</p> Signup and view all the answers

    What molecule is responsible for the 'organification' of the thyroglobulin with iodine?

    <p>Iodinase</p> Signup and view all the answers

    What substance accompanies thyroid peroxidase in promoting the oxidation of iodide ions to iodine?

    <p>Hydrogen peroxide</p> Signup and view all the answers

    Which hormones are commonly known as T4 and T3?

    <p>Triiodothyronine and thyroxine</p> Signup and view all the answers

    What happens to the basal metabolic rate (BMR) when there is a complete lack of thyroid secretion?

    <p>It decreases to 40-50% below normal</p> Signup and view all the answers

    Which hormone controls thyroid secretion primarily?

    <p>Thyroid-stimulating hormone (TSH)</p> Signup and view all the answers

    What percentage of metabolically active hormones secreted by the thyroid gland is thyroxine?

    <p>93%</p> Signup and view all the answers

    What is the primary function of triiodothyronine (T3) and thyroxine (T4)?

    <p>Increase the BMR</p> Signup and view all the answers

    Which hormone is also secreted by the thyroid gland apart from T3 and T4?

    <p>Calcitonin</p> Signup and view all the answers

    What is the main effect of thyroid hormones on gene transcription?

    <p>Activate transcription of large numbers of genes</p> Signup and view all the answers

    How does thyroid hormone affect glucose metabolism?

    <p>Stimulates rapid uptake of glucose by the cells</p> Signup and view all the answers

    Which of the following statements about fat metabolism under thyroid hormone influence is correct?

    <p>Fat metabolism is enhanced</p> Signup and view all the answers

    What is the result of the overall increase in cellular metabolic enzymes caused by thyroid hormone?

    <p>Enhanced synthesis of structural proteins</p> Signup and view all the answers

    Why are thyroid hormones released slowly to tissue cells?

    <p>Because of high affinity of plasma-binding proteins for thyroid hormones</p> Signup and view all the answers

    How does the effect of thyroid hormone on carbohydrate metabolism impact insulin secretion?

    <p>Increases insulin secretion</p> Signup and view all the answers

    What effect does increased thyroid hormone have on the concentrations of cholesterol, phospholipids, and triglycerides in the plasma?

    <p>Decreases cholesterol, phospholipids, and triglycerides</p> Signup and view all the answers

    What is the primary role of lipids when they are mobilized rapidly from fat tissue?

    <p>Accelerate the oxidation of free fatty acids by cells</p> Signup and view all the answers

    How does hyperthyroidism typically affect the size of the thyroid gland in patients?

    <p>Increases the size significantly</p> Signup and view all the answers

    Which protein has the highest binding strength for thyroxine transport in the blood?

    <p>Throxine-binding globulin (TBG)</p> Signup and view all the answers

    What effect does increased thyroid hormone have on the size of the thyroid gland?

    <p>Triples the size</p> Signup and view all the answers

    What physiological consequence results from the rapid mobilization of lipids from fat tissue?

    <p>Accelerates the oxidation of free fatty acids by cells</p> Signup and view all the answers

    What is the underlying cause of hyperthyroidism in Graves' disease?

    <p>Antibodies binding to thyroid cell receptors</p> Signup and view all the answers

    What do thyroid-stimulating immunoglobulins (TSIs) do in individuals with Graves' disease?

    <p>Promote thyroid growth and hormone production</p> Signup and view all the answers

    How does Graves' disease affect the size of the thyroid gland?

    <p>It enlarges the thyroid gland</p> Signup and view all the answers

    What is a common symptom associated with a goiter?

    <p>Swollen neck</p> Signup and view all the answers

    What do radioactive iodine uptake studies indicate in hyperplastic glands?

    <p>Excess thyroid hormone secretion</p> Signup and view all the answers

    In Graves' disease, what role do TSIs play in the production of thyroid hormones?

    <p>Stimulate excess hormone production</p> Signup and view all the answers

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