Podcast
Questions and Answers
What is the drug treatment option for hyperthyroidism?
What is the drug treatment option for hyperthyroidism?
What is the mechanism of action of anti-thyroid drugs (thioamides)?
What is the mechanism of action of anti-thyroid drugs (thioamides)?
Which anti-thyroid drug takes longer to lower thyroid hormone levels but is preferred in the first trimester of pregnancy?
Which anti-thyroid drug takes longer to lower thyroid hormone levels but is preferred in the first trimester of pregnancy?
What are the two drugs used in the treatment of hyperthyroidism?
What are the two drugs used in the treatment of hyperthyroidism?
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What is the preferred anti-thyroid drug for a thyroid storm?
What is the preferred anti-thyroid drug for a thyroid storm?
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What is the black box warning for Propylthiouracil?
What is the black box warning for Propylthiouracil?
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What is the first-line anti-thyroid drug with a quicker onset of lowering thyroid hormones and is safe in the 2nd and 3rd trimester of pregnancy?
What is the first-line anti-thyroid drug with a quicker onset of lowering thyroid hormones and is safe in the 2nd and 3rd trimester of pregnancy?
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What adjunct medication should be considered for patients with hyperthyroidism?
What adjunct medication should be considered for patients with hyperthyroidism?
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What permanent hyperthyroid treatment leads to hypothyroidism
What permanent hyperthyroid treatment leads to hypothyroidism
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Radioactive iodine can be given as a capsule or solution to caused local tissue damage of the thyroid. It is safe in pregnancy.
Radioactive iodine can be given as a capsule or solution to caused local tissue damage of the thyroid. It is safe in pregnancy.
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Beta-blockers are recommended for all hyperthyroidism patients AT DIAGNOSIS (esp if heart is above 100)
Beta-blockers are recommended for all hyperthyroidism patients AT DIAGNOSIS (esp if heart is above 100)
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What is the starting dose of levothyroxine for hypothyroidism in a patient with coronary artery disease (CAD)?
What is the starting dose of levothyroxine for hypothyroidism in a patient with coronary artery disease (CAD)?
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Which medication should be avoided or separated by at least 4 hours from levothyroxine due to its impact on absorption?
Which medication should be avoided or separated by at least 4 hours from levothyroxine due to its impact on absorption?
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What patient education should you give for starting levothyroxine
What patient education should you give for starting levothyroxine
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Levothyroxine is a narrow index drug and needs to remain consistent brand name/generic wise for the patient.
Levothyroxine is a narrow index drug and needs to remain consistent brand name/generic wise for the patient.
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Does this drug increase or decrease thyroid hormone?
Does this drug increase or decrease thyroid hormone?
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You should gradually titrate Levothyroxine up by ___ to ___ mcg every 4-6 weeks based on TSH and clinical response until at goal.
You should gradually titrate Levothyroxine up by ___ to ___ mcg every 4-6 weeks based on TSH and clinical response until at goal.
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Levothyroxine is the thyroid hormone replacement drug of choice.
Levothyroxine is the thyroid hormone replacement drug of choice.
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What hypothyroidism treatment was traditionally used to alleviate symptoms associated with thyroid cancer, but is less commonly used today due to dose flutuations?
What hypothyroidism treatment was traditionally used to alleviate symptoms associated with thyroid cancer, but is less commonly used today due to dose flutuations?
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What hypothyroid drug is made from animal thyroid hormones and therefore has more allergies and dietary restrictions?
What hypothyroid drug is made from animal thyroid hormones and therefore has more allergies and dietary restrictions?
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Order of improvement when treating hypothyroidism
Order of improvement when treating hypothyroidism
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What is the drug of choice for treating hypothyroidism in pregnancy?
What is the drug of choice for treating hypothyroidism in pregnancy?
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Study Notes
Hyperthyroidism Treatment
- Thioamides (anti-thyroid drugs) are the drug treatment option for hyperthyroidism.
- They block the synthesis of thyroid (T3/T4) hormones.
Mechanism of Action of Anti-Thyroid Drugs
- Anti-thyroid drugs (thioamides) block the synthesis of thyroid (T3/T4) hormones.
Anti-Thyroid Drugs for Hyperthyroidism
- Two drugs used in the treatment of hyperthyroidism are Propylthiouracil and Methimazole.
Propylthiouracil
- Takes longer to lower thyroid hormone levels, but is preferred in the first trimester of pregnancy.
- Is the preferred anti-thyroid drug for thyroid storm.
- Has a black box warning for Hepatotoxicity.
Methimazole
- Is the first-line anti-thyroid drug with a quicker onset of lowering thyroid hormones.
- Is safe in the 2nd and 3rd trimester of pregnancy.
Hypothyroidism Treatment
- Levothyroxine is the preferred drug of choice for hypothyroidism.
- The starting dose of Levothyroxine for hypothyroidism is 100 mcg/day for a young and healthy patient.
- For a patient with CAD, the starting dose is 25 mcg/day regardless of age.
Patient Education for Levothyroxine
- Take Levothyroxine on an empty stomach 30-60 minutes before a meal or at bedtime.
Drug Interactions
- Warfarin is known to increase thyroid hormone levels.
- Patients should wait 4 hours to take Levothyroxine after taking a calcium, iron, or bile acid supplement.
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Description
Test your knowledge on drug treatment for hyperthyroidism with this quiz. Learn about the different drug options available and their mechanisms of action. Perfect for medical students and healthcare professionals.
