Podcast
Questions and Answers
Which of the following best describes the mechanism of thyroid hormone action?
Which of the following best describes the mechanism of thyroid hormone action?
- Inhibiting gene transcription to regulate metabolism
- Increasing protein synthesis to stimulate cellular metabolism (correct)
- Binding to surface receptors to stimulate adenylate cyclase
- Stimulating the release of neurotransmitters to regulate appetite
What is the primary function of the hypothalamus in regulating thyroid function?
What is the primary function of the hypothalamus in regulating thyroid function?
- To regulate the release of thyroid hormones from the thyroid gland
- To stimulate the synthesis of thyroglobulin
- To secrete thyroid-stimulating hormone (TSH)
- To produce thyrotropin-releasing hormone (TRH) to stimulate the pituitary (correct)
Which of the following are results of hyperthyroidism?
Which of the following are results of hyperthyroidism?
- Increased appetite and weight loss (correct)
- Decreased protein synthesis and muscle atrophy
- Increased synthesis of thyroid hormones and weight gain
- Decreased metabolic rate and weight gain
What is the primary function of the pituitary in regulating thyroid function?
What is the primary function of the pituitary in regulating thyroid function?
Approximately, what is the percentage of T4 and T3 that is bound to plasma proteins?
Approximately, what is the percentage of T4 and T3 that is bound to plasma proteins?
What is the result of the outer ring deiodination of T4?
What is the result of the outer ring deiodination of T4?
What is the primary function of thyroid hormone T3?
What is the primary function of thyroid hormone T3?
What is the result of the hydrolysis of thyroglobulin in lysosomal pathway?
What is the result of the hydrolysis of thyroglobulin in lysosomal pathway?
What is the function of thyroid-binding globulin?
What is the function of thyroid-binding globulin?
What is the primary mechanism of action of T3 in the nucleus?
What is the primary mechanism of action of T3 in the nucleus?
What is the percentage of T3 and T4 that binds to thyroid-binding globulin (TBG) or transthyretin (TTR) in the plasma?
What is the percentage of T3 and T4 that binds to thyroid-binding globulin (TBG) or transthyretin (TTR) in the plasma?
What is the mechanism by which T4 is converted to T3 in the cytosol?
What is the mechanism by which T4 is converted to T3 in the cytosol?
What is the percentage of T3 that is released from the thyroid gland?
What is the percentage of T3 that is released from the thyroid gland?
What is the name of the protein that T3 and T4 bind to in the plasma?
What is the name of the protein that T3 and T4 bind to in the plasma?
What is the effect of excess TSH on the thyroid gland?
What is the effect of excess TSH on the thyroid gland?
What is the most common form of hyperthyroidism?
What is the most common form of hyperthyroidism?
What is the diagnosis of hyperthyroidism based on?
What is the diagnosis of hyperthyroidism based on?
What is the anesthetic concern in hyperthyroidism?
What is the anesthetic concern in hyperthyroidism?
What is the preoperative management of hyperthyroidism in emergency surgery?
What is the preoperative management of hyperthyroidism in emergency surgery?
What is the potential complication of goiter during thyroid surgery?
What is the potential complication of goiter during thyroid surgery?
Which of the following is not essential for normal biosynthesis of thyroid hormones?
Which of the following is not essential for normal biosynthesis of thyroid hormones?
What is the effect of an increase in plasma levels of TSH alone have on metabolic rate?
What is the effect of an increase in plasma levels of TSH alone have on metabolic rate?
In which condition is the TSH response to TRH most likely to be reduced?
In which condition is the TSH response to TRH most likely to be reduced?
What is the effect of TSH injections on thyroidal uptake of iodine?
What is the effect of TSH injections on thyroidal uptake of iodine?
Which of the following hormones is least affected by an increase in plasma levels of TRH?
Which of the following hormones is least affected by an increase in plasma levels of TRH?