Thrombotic Microangiopathy Lecture Notes
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Questions and Answers

What is the primary cause of excessive C3 activation in a particular microangiopathic syndrome?

  • Coagulation system disorder
  • Excess of factor H
  • Deficiency of factor H (correct)
  • Activation of platelets

    • What is the current limitation of kidney transplant in treating a specific microangiopathic syndrome?

  • It is a complex surgery
  • It is not available worldwide
  • It fails to cure the disease (correct)
  • It is very expensive

    • Why is gene therapy considered the only cure for a specific microangiopathic syndrome?

  • It replaces the deficient factor permanently (correct)
  • It is a non-invasive treatment
  • It is a cost-effective treatment
  • It has no side effects

    • What is a characteristic feature of the acquired form of haemolytic uraemic syndrome?

    <p>Neurologic manifestation is absent</p> Signup and view all the answers

    What is a common complication of preeclampsia?

    <p>All of the above</p> Signup and view all the answers

    What is a characteristic feature of thrombotic microangiopathy in pregnancy and the postpartum period?

    <p>It involves multiple organs</p> Signup and view all the answers

    What is a hematologic complication of thrombotic microangiopathy in pregnancy and the postpartum period?

    <p>MAHA with characteristic fragmented red cells</p> Signup and view all the answers

    What is a treatment modality for the acquired form of haemolytic uraemic syndrome?

    <p>Similar to that of TTP</p> Signup and view all the answers

    What is a condition associated with the post-partum period?

    <p>Postpartum hemolytic uraemic syndrome (HUS)</p> Signup and view all the answers

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