Thrombotic Microangiopathy Lecture Notes

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9 Questions

What is the primary cause of excessive C3 activation in a particular microangiopathic syndrome?

Deficiency of factor H

What is the current limitation of kidney transplant in treating a specific microangiopathic syndrome?

It fails to cure the disease

Why is gene therapy considered the only cure for a specific microangiopathic syndrome?

It replaces the deficient factor permanently

What is a characteristic feature of the acquired form of haemolytic uraemic syndrome?

Neurologic manifestation is absent

What is a common complication of preeclampsia?

All of the above

What is a characteristic feature of thrombotic microangiopathy in pregnancy and the postpartum period?

It involves multiple organs

What is a hematologic complication of thrombotic microangiopathy in pregnancy and the postpartum period?

MAHA with characteristic fragmented red cells

What is a treatment modality for the acquired form of haemolytic uraemic syndrome?

Similar to that of TTP

What is a condition associated with the post-partum period?

Postpartum hemolytic uraemic syndrome (HUS)

Explore the lecture notes by Dr. Helen C. Okoye covering Thrombotic Microangiopathy (TTP), Hemolytic Uremic Syndrome (HUS), and HELLP syndrome. Learn about the introduction, definition, aetiology, and occurrence of microangiopathy in pregnancy.

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