Thrombosis Lecture Learning Outcomes

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Questions and Answers

What is the main pathogenetic mechanism for arterial thrombi?

  • Stasis and hypercoagulability
  • Endothelial cell injury and turbulence (correct)
  • Volvulus and intestinal obstruction
  • Congestive heart failure and burns

Which of the following is a common location for venous thrombi?

  • Coronary arteries
  • Aorta
  • Deep veins of the lower limbs (correct)
  • Pulmonary arteries

Which of the following is a clinical association of arterial thrombi in the arteries of the limbs?

  • Arteritis
  • Diabetes mellitus and Buerger's disease (correct)
  • Atherosclerosis
  • Aneurysms

What is the main pathogenetic mechanism for venous thrombi?

<p>Stasis and hypercoagulability (D)</p> Signup and view all the answers

Which of the following is a clinical association of venous thrombi in the pulmonary veins?

<p>Congestive heart failure and pulmonary hypertension (B)</p> Signup and view all the answers

How is the composition of a thrombus determined?

<p>By the rate of blood flow at the site of origin (C)</p> Signup and view all the answers

What is the characteristic appearance of arterial and cardiac (mural) thrombi?

<p>Laminations with lines of Zahn (A)</p> Signup and view all the answers

Which type of thrombi typically contain abundant erythrocytes among sparse fibrin strands?

<p>Venous thrombi (B)</p> Signup and view all the answers

What is the typical color and morphology of valve thrombosis (vegetations)?

<p>Red-brown and granular (A)</p> Signup and view all the answers

What happens if a patient survives the immediate effects of a thrombus?

<p>Organization and recanalization (A)</p> Signup and view all the answers

What type of thrombi are firmly attached at their site of origin and typically propagate toward the heart?

<p>Cardiac (mural) thrombi (B)</p> Signup and view all the answers

How do arterial and cardiac (mural) thrombi differ in composition from venous thrombi?

<p>Have more fibrin strands (C)</p> Signup and view all the answers

What distinguishes a thrombus from a blood clot?

<p>Thrombus involves activation of platelets, while a blood clot does not. (D)</p> Signup and view all the answers

In which situations may a blood clot occur?

<p>Coagulation of blood in vitro. (C)</p> Signup and view all the answers

How does thrombosis differ from hemostatic plugs?

<p>Thrombosis occurs in uninjured vasculature, while hemostatic plugs form at injury sites. (C)</p> Signup and view all the answers

What is the main difference between a thrombus and a hematoma?

<p>Thrombus involves vascular attachment, while hematoma is an extravascular accumulation. (C)</p> Signup and view all the answers

How does a thrombus differ from a coagulated blood after death?

<p>A thrombus forms in an intact blood vessel during life, unlike coagulated blood after death. (C)</p> Signup and view all the answers

What characterizes hemostatic plugs compared to thrombi?

<p>Hemostatic plugs are formed in healthy individuals at the site of injury, unlike thrombi. (B)</p> Signup and view all the answers

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