Thrombosis Lecture Learning Outcomes

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What is the main pathogenetic mechanism for arterial thrombi?

Stasis and hypercoagulability

Endothelial cell injury and turbulence (correct)

Volvulus and intestinal obstruction

Congestive heart failure and burns

Which of the following is a common location for venous thrombi?

Coronary arteries

Aorta

Deep veins of the lower limbs (correct)

Pulmonary arteries

Which of the following is a clinical association of arterial thrombi in the arteries of the limbs?

Arteritis

Diabetes mellitus and Buerger's disease (correct)

Atherosclerosis

Aneurysms

What is the main pathogenetic mechanism for venous thrombi?

Stasis and hypercoagulability Signup and view all the answers

Which of the following is a clinical association of venous thrombi in the pulmonary veins?

Congestive heart failure and pulmonary hypertension Signup and view all the answers

How is the composition of a thrombus determined?

By the rate of blood flow at the site of origin Signup and view all the answers

What is the characteristic appearance of arterial and cardiac (mural) thrombi?

Laminations with lines of Zahn Signup and view all the answers

Which type of thrombi typically contain abundant erythrocytes among sparse fibrin strands?

Venous thrombi Signup and view all the answers

What is the typical color and morphology of valve thrombosis (vegetations)?

Red-brown and granular Signup and view all the answers

What happens if a patient survives the immediate effects of a thrombus?

Organization and recanalization Signup and view all the answers

What type of thrombi are firmly attached at their site of origin and typically propagate toward the heart?

Cardiac (mural) thrombi Signup and view all the answers

How do arterial and cardiac (mural) thrombi differ in composition from venous thrombi?

Have more fibrin strands Signup and view all the answers

What distinguishes a thrombus from a blood clot?

Thrombus involves activation of platelets, while a blood clot does not. Signup and view all the answers

In which situations may a blood clot occur?

Coagulation of blood in vitro. Signup and view all the answers

How does thrombosis differ from hemostatic plugs?

Thrombosis occurs in uninjured vasculature, while hemostatic plugs form at injury sites. Signup and view all the answers

What is the main difference between a thrombus and a hematoma?

Thrombus involves vascular attachment, while hematoma is an extravascular accumulation. Signup and view all the answers

How does a thrombus differ from a coagulated blood after death?

A thrombus forms in an intact blood vessel during life, unlike coagulated blood after death. Signup and view all the answers

What characterizes hemostatic plugs compared to thrombi?

Hemostatic plugs are formed in healthy individuals at the site of injury, unlike thrombi. Signup and view all the answers