Blood Clot & Antithrombotics

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What is the mechanism by which elevated cAMP levels affect thromboxane A2 activity?

Blocking the release of arachidonic acid

Which of the following substances is greatly attenuated by Cilostazol in platelet aggregation?

ADP

What is a therapeutic application of Vitamin K?

Correcting bleeding tendency due to its deficiency

Which of the following can result in Vitamin K deficiency?

<p>Inadequate intake of Vitamin K</p> Signup and view all the answers

How are Phylloquinone derivatives like Aquamephyton, Konakion, Mephyton typically administered?

<p>Intravenously as injections</p> Signup and view all the answers

What is the primary function of the system of fibrinolysis when intravascular thrombus occurs?

<p>To restore blood fluidity</p> Signup and view all the answers

In healthy conditions, what is essential to prevent both thrombosis and hemorrhage?

<p>Maintaining a balance between pro-coagulants and anticoagulants</p> Signup and view all the answers

Which category of antithrombotics includes drugs that inhibit platelet function?

<p>Antiplatelet agents</p> Signup and view all the answers

What is the primary therapeutic goal of administering an anticoagulant?

<p>Prevent blood clot formation</p> Signup and view all the answers

What adverse effect can be observed when overdosing on an anticoagulant?

<p>Excessive bleeding</p> Signup and view all the answers

Which antithrombotic drug is a glycosaminoglycan found in the secretory granules of mast cells?

<p>Heparin</p> Signup and view all the answers

Which drug is classified as a platelet aggregation inhibitor?

<p>Clopidogrel</p> Signup and view all the answers

What is the mechanism of action of thienopyridines like Ticlopidine?

<p>Inhibiting adenosine diphosphate-induced platelet aggregation</p> Signup and view all the answers

Which of the following drugs is a protease-activated receptor-1 antagonist?

<p>Vorapaxar</p> Signup and view all the answers

What is the main target of glycoprotein platelet inhibitors like Abciximab?

<p>Glycoprotein IIb/IIIa receptors</p> Signup and view all the answers

Among the thienopyridines mentioned, which drug is known for being the most potent with a rapid onset of action?

<p>Prasugrel</p> Signup and view all the answers

What is the main inhibitory effect of Dipyridamole on platelet function?

<p>Inhibiting phosphodiesterase type 3</p> Signup and view all the answers

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