Blood Clot & Antithrombotics
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Questions and Answers

What is the mechanism by which elevated cAMP levels affect thromboxane A2 activity?

  • Blocking the release of arachidonic acid (correct)
  • Enhancing the release of arachidonic acid
  • Attenuating platelet aggregation
  • Increasing the activity of thromboxane A2

    • Which of the following substances is greatly attenuated by Cilostazol in platelet aggregation?

  • Vitamin K
  • Epinephrine
  • Collagen
  • ADP (correct)

    • What is a therapeutic application of Vitamin K?

  • Improving endothelial cell function
  • Reducing platelet aggregation
  • Enhancing thromboxane A2 activity
  • Correcting bleeding tendency due to its deficiency (correct)

    • Which of the following can result in Vitamin K deficiency?

    <p>Inadequate intake of Vitamin K</p> Signup and view all the answers

    How are Phylloquinone derivatives like Aquamephyton, Konakion, Mephyton typically administered?

    <p>Intravenously as injections</p> Signup and view all the answers

    What is the primary function of the system of fibrinolysis when intravascular thrombus occurs?

    <p>To restore blood fluidity</p> Signup and view all the answers

    In healthy conditions, what is essential to prevent both thrombosis and hemorrhage?

    <p>Maintaining a balance between pro-coagulants and anticoagulants</p> Signup and view all the answers

    Which category of antithrombotics includes drugs that inhibit platelet function?

    <p>Antiplatelet agents</p> Signup and view all the answers

    What is the primary therapeutic goal of administering an anticoagulant?

    <p>Prevent blood clot formation</p> Signup and view all the answers

    What adverse effect can be observed when overdosing on an anticoagulant?

    <p>Excessive bleeding</p> Signup and view all the answers

    Which antithrombotic drug is a glycosaminoglycan found in the secretory granules of mast cells?

    <p>Heparin</p> Signup and view all the answers

    Which drug is classified as a platelet aggregation inhibitor?

    <p>Clopidogrel</p> Signup and view all the answers

    What is the mechanism of action of thienopyridines like Ticlopidine?

    <p>Inhibiting adenosine diphosphate-induced platelet aggregation</p> Signup and view all the answers

    Which of the following drugs is a protease-activated receptor-1 antagonist?

    <p>Vorapaxar</p> Signup and view all the answers

    What is the main target of glycoprotein platelet inhibitors like Abciximab?

    <p>Glycoprotein IIb/IIIa receptors</p> Signup and view all the answers

    Among the thienopyridines mentioned, which drug is known for being the most potent with a rapid onset of action?

    <p>Prasugrel</p> Signup and view all the answers

    What is the main inhibitory effect of Dipyridamole on platelet function?

    <p>Inhibiting phosphodiesterase type 3</p> Signup and view all the answers

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