Therapeutic Uses of Progestogens Quiz
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Questions and Answers

What hormone is released from the corpus luteum and stimulates the onset of menstruation?

  • Progesterone (correct)
  • Prolactin
  • Estrogen
  • Testosterone

Why is progesterone by itself not widely used as a contraceptive therapy?

  • Rapid metabolism and low bioavailability (correct)
  • High bioavailability
  • Slow metabolism
  • No side effects

Which synthetic progestogen used in contraception is more stable to first-pass metabolism?

  • Estrogen
  • Levonorgestrel (correct)
  • Medroxyprogesterone acetate
  • Norgestimate

What is the injectable contraceptive that lasts for 3 months?

<p>Medroxyprogesterone acetate (A)</p> Signup and view all the answers

Which progestin component is common in postmenopausal hormone therapy?

<p>Norgestimate (D)</p> Signup and view all the answers

Why are less androgenic progestins like norgestimate preferred in women with acne?

<p>They possess some androgenic activity (D)</p> Signup and view all the answers

Which type of contraceptives contains a combination of an estrogen and a progestin?

<p>Oral contraceptives (B)</p> Signup and view all the answers

What is the effect of administration of Mifepristone early in pregnancy?

<p>Induces abortion (A)</p> Signup and view all the answers

Which of the following contraceptives mimic the natural female cycle?

<p>Monophasic combination pills (D)</p> Signup and view all the answers

What is the most common estrogen found in combination pills?

<p>Ethinyl estradiol (A)</p> Signup and view all the answers

How do triphasic oral contraceptives differ from monophasic combination pills?

<p>Triphasic contain increasing doses of progestin over 3 weeks (B)</p> Signup and view all the answers

What is the mechanism behind Drospirenone's effect on serum potassium levels?

<p>It reduces potassium reabsorption (C)</p> Signup and view all the answers

Which condition contraindicates the use of oral contraceptives?

<p>Liver disease (A)</p> Signup and view all the answers

In whom should combination oral contraceptives NOT be used?

<p>Patients over 35 who are heavy smokers (A)</p> Signup and view all the answers

Which enzyme induction leads to decreased efficacy of oral contraceptives?

<p>CYP3A4 (C)</p> Signup and view all the answers

How do antibiotics affect the effectiveness of oral contraceptives?

<p>Increase metabolism of estrogen component (C)</p> Signup and view all the answers

Which group of steroids have anabolic and masculinizing effects?

<p>Androgens (C)</p> Signup and view all the answers

What controls the secretion of testosterone by Leydig cells in adult males?

<p>FSH and LH from the hypothalamus (B)</p> Signup and view all the answers

Which injectable progestin is administered every 3 months?

<p>Medroxyprogesterone acetate (A)</p> Signup and view all the answers

What are the possible adverse effects of medroxyprogesterone acetate?

<p>Weight gain, amenorrhea, delayed fertility, and bone loss (C)</p> Signup and view all the answers

Which progestin contraception is most suitable for long-term use?

<p>Progestin intrauterine device (B)</p> Signup and view all the answers

What is the principal side effect of progestin implants?

<p>Irregular menstrual bleeding and headaches (A)</p> Signup and view all the answers

Which contraceptive method should be avoided in patients with pelvic inflammatory disease?

<p>Progestin intrauterine device (B)</p> Signup and view all the answers

Which hormone is used in high doses for emergency contraception?

<p>Levonorgestrel (B)</p> Signup and view all the answers

What is the role of testosterone and its active metabolite, DHT, in inhibiting FSH & LH production?

<p>Inhibits FSH &amp; LH production through negative feedback (A)</p> Signup and view all the answers

Which of the following is NOT a function of androgens like testosterone?

<p>Increased bone resorption (A)</p> Signup and view all the answers

Where does testosterone need to be metabolized to DHT for binding to the receptor in certain tissues?

<p>Prostate, seminal vesicles, epididymis, and skin (B)</p> Signup and view all the answers

Which condition is NOT a therapeutic use of anabolic steroids?

<p>Antiaging effects (D)</p> Signup and view all the answers

What is the main mechanism of action for androgens like testosterone in target cells?

<p>Binding to specific nuclear receptors (D)</p> Signup and view all the answers

Which hormone has been promoted as an antiaging hormone and a 'performance enhancer' despite lack of definitive evidence?

<p>DHEA (B)</p> Signup and view all the answers

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