Therapeutic Uses of Progestogens Quiz
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Questions and Answers

What hormone is released from the corpus luteum and stimulates the onset of menstruation?

  • Progesterone (correct)
  • Prolactin
  • Estrogen
  • Testosterone
  • Why is progesterone by itself not widely used as a contraceptive therapy?

  • Rapid metabolism and low bioavailability (correct)
  • High bioavailability
  • Slow metabolism
  • No side effects
  • Which synthetic progestogen used in contraception is more stable to first-pass metabolism?

  • Estrogen
  • Levonorgestrel (correct)
  • Medroxyprogesterone acetate
  • Norgestimate
  • What is the injectable contraceptive that lasts for 3 months?

    <p>Medroxyprogesterone acetate</p> Signup and view all the answers

    Which progestin component is common in postmenopausal hormone therapy?

    <p>Norgestimate</p> Signup and view all the answers

    Why are less androgenic progestins like norgestimate preferred in women with acne?

    <p>They possess some androgenic activity</p> Signup and view all the answers

    Which type of contraceptives contains a combination of an estrogen and a progestin?

    <p>Oral contraceptives</p> Signup and view all the answers

    What is the effect of administration of Mifepristone early in pregnancy?

    <p>Induces abortion</p> Signup and view all the answers

    Which of the following contraceptives mimic the natural female cycle?

    <p>Monophasic combination pills</p> Signup and view all the answers

    What is the most common estrogen found in combination pills?

    <p>Ethinyl estradiol</p> Signup and view all the answers

    How do triphasic oral contraceptives differ from monophasic combination pills?

    <p>Triphasic contain increasing doses of progestin over 3 weeks</p> Signup and view all the answers

    What is the mechanism behind Drospirenone's effect on serum potassium levels?

    <p>It reduces potassium reabsorption</p> Signup and view all the answers

    Which condition contraindicates the use of oral contraceptives?

    <p>Liver disease</p> Signup and view all the answers

    In whom should combination oral contraceptives NOT be used?

    <p>Patients over 35 who are heavy smokers</p> Signup and view all the answers

    Which enzyme induction leads to decreased efficacy of oral contraceptives?

    <p>CYP3A4</p> Signup and view all the answers

    How do antibiotics affect the effectiveness of oral contraceptives?

    <p>Increase metabolism of estrogen component</p> Signup and view all the answers

    Which group of steroids have anabolic and masculinizing effects?

    <p>Androgens</p> Signup and view all the answers

    What controls the secretion of testosterone by Leydig cells in adult males?

    <p>FSH and LH from the hypothalamus</p> Signup and view all the answers

    Which injectable progestin is administered every 3 months?

    <p>Medroxyprogesterone acetate</p> Signup and view all the answers

    What are the possible adverse effects of medroxyprogesterone acetate?

    <p>Weight gain, amenorrhea, delayed fertility, and bone loss</p> Signup and view all the answers

    Which progestin contraception is most suitable for long-term use?

    <p>Progestin intrauterine device</p> Signup and view all the answers

    What is the principal side effect of progestin implants?

    <p>Irregular menstrual bleeding and headaches</p> Signup and view all the answers

    Which contraceptive method should be avoided in patients with pelvic inflammatory disease?

    <p>Progestin intrauterine device</p> Signup and view all the answers

    Which hormone is used in high doses for emergency contraception?

    <p>Levonorgestrel</p> Signup and view all the answers

    What is the role of testosterone and its active metabolite, DHT, in inhibiting FSH & LH production?

    <p>Inhibits FSH &amp; LH production through negative feedback</p> Signup and view all the answers

    Which of the following is NOT a function of androgens like testosterone?

    <p>Increased bone resorption</p> Signup and view all the answers

    Where does testosterone need to be metabolized to DHT for binding to the receptor in certain tissues?

    <p>Prostate, seminal vesicles, epididymis, and skin</p> Signup and view all the answers

    Which condition is NOT a therapeutic use of anabolic steroids?

    <p>Antiaging effects</p> Signup and view all the answers

    What is the main mechanism of action for androgens like testosterone in target cells?

    <p>Binding to specific nuclear receptors</p> Signup and view all the answers

    Which hormone has been promoted as an antiaging hormone and a 'performance enhancer' despite lack of definitive evidence?

    <p>DHEA</p> Signup and view all the answers

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