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Progesterone Benefits and Role in Preventing Preterm Labor
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Progesterone Benefits and Role in Preventing Preterm Labor

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Questions and Answers

What role does progesterone play in preventing preterm labor?

  • Stimulation of cervical stromal degradation
  • Promotion of myometrial activation
  • Decreased prostaglandin synthesis (correct)
  • Enhancement of inflammatory response

    • Which of the following is NOT a beneficial effect of progesterone mentioned in the text?

  • Regulation of the inflammatory response
  • Promotion of gap junction development (correct)
  • Suppression of cervical stromal degradation
  • Prevention of myometrial activation

    • In high-risk pregnancies, progesterone may be used to prevent premature birth based on evidence. What type of pregnancies are specifically mentioned as benefiting from progesterone prophylaxis?

  • Pregnancies with high maternal age
  • Pregnancies with multiple gestations
  • Pregnancies with a history of spontaneous preterm delivery (correct)
  • Pregnancies with a history of full-term delivery

    • Why is progestogen usage an area of continued interest and research?

    <p>Due to its possible impact on reducing the incidence of preterm birth</p> Signup and view all the answers

    What forms the basis of the understanding of how progesterone prevents preterm labor?

    <p>Reduction in sensitivity to estrogen</p> Signup and view all the answers

    How does progesterone affect myometrial function?

    <p>By time-dependently stimulating nitric oxide synthetase (NOS)</p> Signup and view all the answers

    What effect does progesterone have on cyclic adenosine monophosphate (cAMP) levels?

    <p>It increases cAMP levels in a time-dependent manner</p> Signup and view all the answers

    What is the impact of progesterone on gap junctions' formation within the myometrium?

    <p>It inhibits the formation of gap junctions.</p> Signup and view all the answers

    What is the main way through which progesterone relaxes the uterus during pregnancy?

    <p>By suppressing ER-a development</p> Signup and view all the answers

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