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Progesterone Benefits and Role in Preventing Preterm Labor

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Progesterone Benefits and Role in Preventing Preterm Labor

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Questions and Answers

What role does progesterone play in preventing preterm labor?

Stimulation of cervical stromal degradation
Promotion of myometrial activation
Decreased prostaglandin synthesis (correct)
Enhancement of inflammatory response

Which of the following is NOT a beneficial effect of progesterone mentioned in the text?

Regulation of the inflammatory response
Promotion of gap junction development (correct)
Suppression of cervical stromal degradation
Prevention of myometrial activation

In high-risk pregnancies, progesterone may be used to prevent premature birth based on evidence. What type of pregnancies are specifically mentioned as benefiting from progesterone prophylaxis?

Pregnancies with high maternal age
Pregnancies with multiple gestations
Pregnancies with a history of spontaneous preterm delivery (correct)
Pregnancies with a history of full-term delivery

Why is progestogen usage an area of continued interest and research?

Due to its possible impact on reducing the incidence of preterm birth (A) Signup and view all the answers

What forms the basis of the understanding of how progesterone prevents preterm labor?

Reduction in sensitivity to estrogen (C) Signup and view all the answers

How does progesterone affect myometrial function?

By time-dependently stimulating nitric oxide synthetase (NOS) (D) Signup and view all the answers

What effect does progesterone have on cyclic adenosine monophosphate (cAMP) levels?

It increases cAMP levels in a time-dependent manner (B) Signup and view all the answers

What is the impact of progesterone on gap junctions' formation within the myometrium?

It inhibits the formation of gap junctions. (B) Signup and view all the answers

What is the main way through which progesterone relaxes the uterus during pregnancy?

By suppressing ER-a development (A) Signup and view all the answers