Therapeutic Drug Monitoring Quiz

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Questions and Answers

Which drugs are particularly useful for therapeutic drug monitoring?

  • Digoxin and theophylline
  • Antidepressants and lithium
  • Antibiotics and tricyclic antidepressants
  • Anticonvulsants and aminoglycoside antibiotics (correct)

When is therapeutic drug monitoring especially useful?

  • When the drug concentration is not critical
  • During initial stages of treatment
  • In case of failure of response without any apparent reason (correct)
  • When the patient is responsive to treatment

What is the aim of therapeutic drug monitoring?

  • To monitor adverse drug reactions
  • To minimize drug concentration in the body
  • To maximize drug concentration in the body
  • To ensure that drug concentration lies within the therapeutic range (correct)

Why is timing of blood samples crucial for aminoglycosides?

<p>To obtain peak and trough concentrations (D)</p> Signup and view all the answers

In what situations is therapeutic drug monitoring particularly useful?

<p>Multidrug therapy with possible drug interactions (D)</p> Signup and view all the answers

What is the aim of therapeutic drug monitoring?

<p>To ensure drug concentration lies within the therapeutic range (C)</p> Signup and view all the answers

In what situation is therapeutic drug monitoring particularly useful?

<p>When individual variations of drug response are large (C)</p> Signup and view all the answers

Why is timing of blood samples crucial for aminoglycosides in therapeutic drug monitoring?

<p>To measure peak and trough concentrations (B)</p> Signup and view all the answers

Which type of drugs are suitable candidates for therapeutic drug monitoring?

<p>Anticonvulsants and antibiotics (C)</p> Signup and view all the answers

When can blood samples be obtained to guide chronic therapy with anticonvulsants?

<p>After sufficient time has elapsed for the steady state to have been achieved (C)</p> Signup and view all the answers

Flashcards

Therapeutic drug monitoring

Monitoring drug levels in the blood to ensure they are within a safe and effective range.

Drugs suitable for therapeutic monitoring

Drugs like anticonvulsants and aminoglycosides, where blood levels directly impact effectiveness and safety.

When therapeutic drug monitoring is especially useful

When a patient isn't responding to treatment as expected, despite no apparent reason.

Why timing of blood samples is crucial for aminoglycosides

To measure the highest (peak) and lowest (trough) concentration of the antibiotic in the blood.

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Situation where therapeutic drug monitoring is useful

When using multiple drugs, as interactions can influence drug levels.

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When is therapeutic drug monitoring useful?

When individuals respond to drugs differently, needing personalized dosage adjustments.

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What is the goal of aminoglycoside blood sampling timing?

To measure "peak" concentration (highest) and "trough" concentration (lowest), crucial for aminoglycosides effectiveness and safety.

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What types of drugs are suitable for therapeutic drug monitoring?

Drugs like anticonvulsants and antibiotics, where blood levels are closely linked to their effects.

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When can blood samples be obtained for anticonvulsants?

After the drug has reached a steady state in the body, meaning the drug levels are consistent.

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