The Sympathetic Vasoconstrictor Mediator
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Questions and Answers

Which blood vessels have the lowest pressure and vascular resistance?

  • Veins
  • Pulmonary arteries
  • Pulmonary veins (correct)
  • Arteries
  • What is the primary goal of the pulmonary circulation?

  • To carry metabolic waste products from the tissues
  • To remove carbon dioxide from the tissues
  • To carry oxygen from the lungs to the tissues (correct)
  • To carry nutrients from the digestive tract to the tissues
  • Which blood vessel receives output from the left ventricle?

  • Pulmonary vein
  • Pulmonary artery
  • Aorta (correct)
  • Arteries
  • What is the purpose of blood flow redistribution during exercise?

    <p>To direct blood to areas with greater metabolic need</p> Signup and view all the answers

    Which layer of blood vessels is composed of concentric layers of smooth muscle cells?

    <p>Tunica media</p> Signup and view all the answers

    Which type of blood vessels have uniquely thin walls composed of only endothelial cells and basement membrane?

    <p>Capillaries</p> Signup and view all the answers

    What is the primary site of systemic vascular resistance in the circulatory system?

    <p>Arterioles</p> Signup and view all the answers

    What is the relationship between wall tension (T), pressure (P), and radius (r) in blood vessels?

    <p>T = P/r</p> Signup and view all the answers

    Which of the following is the main factor controlling vascular resistance on a minute-to-minute basis?

    <p>Radius of the vessel</p> Signup and view all the answers

    Which site represents the primary site of vascular resistance maintaining normal blood pressure?

    <p>Resistance arterioles</p> Signup and view all the answers

    Which of the following hormones is responsible for vasoconstriction and increasing blood pressure?

    <p>Angiotensin II</p> Signup and view all the answers

    Which endothelium-derived vasodilator plays a role in maintaining normal blood flow?

    <p>Prostacyclin (PGI2)</p> Signup and view all the answers

    Which mediator is responsible for preventing orthostatic hypotension?

    <p>Epinephrine</p> Signup and view all the answers

    Which mediator is primarily responsible for sodium and blood volume regulation?

    <p>Angiotensin II</p> Signup and view all the answers

    Which mediator plays a major role in water conservation by the kidneys?

    <p>Vasopressin</p> Signup and view all the answers

    Which mediator is released from white blood cells in the process of inflammatory responses?

    <p>PGD2</p> Signup and view all the answers

    Which hypothesis of autoregulation suggests that decreased pressure and flow result in buildup of vasodilator metabolites that produce vasodilation, while increased pressure and flow wash out vasodilator metabolites, producing vasoconstriction?

    <p>Metabolic hypothesis</p> Signup and view all the answers

    What is the key regulator of adrenal aldosterone secretion?

    <p>Angiotensin II</p> Signup and view all the answers

    Which receptor is activated by vasopressin (AVP) to cause vasoconstriction?

    <p>V1</p> Signup and view all the answers

    Which second messenger is involved in the vasodilation mediated by nitric oxide (NO)?

    <p>cGMP</p> Signup and view all the answers

    According to the Law of Laplace, which of the following occurs when the arterial wall weakens in response to increased pressure?

    <p>Aneurysm</p> Signup and view all the answers

    Which type of blood vessels are less compliant than veins but are subjected to greater pressure changes as they receive the stroke volume of the heart during systole?

    <p>Arteries</p> Signup and view all the answers

    Which blood vessels contain an abundance of elastic fibers that stretch during systole and return to their original shape and size during diastole?

    <p>Arteries</p> Signup and view all the answers

    Which of the following is the most important biochemical mediator produced by endothelial cells and smooth muscle layers, promoting vasodilation, maintaining vessel patency, and lowering blood pressure?

    <p>Nitric oxide (NO)</p> Signup and view all the answers

    Which of the following is the most likely cause of the 32-year-old female's fainting spell?

    <p>Increased firing of parasympathetic fibers to the heart</p> Signup and view all the answers

    Which of the following baroreflex compensatory responses will not occur in response to an acute drop in blood pressure?

    <p>Increased firing of sympathetic nerves to the kidney stimulating renin release</p> Signup and view all the answers

    Which of the following is a possible cause of primary hypertension?

    <p>Coarctation of the aorta</p> Signup and view all the answers

    Which of the following is a possible cause of secondary hypertension?

    <p>Renal disease</p> Signup and view all the answers

    Which of the following hypotheses of origin for hypertension predicts vasoconstriction by generalized autoregulation?

    <p>Initial defect in sodium and water retention</p> Signup and view all the answers

    Which of the following hypotheses of origin for hypertension involves increased sympathetic tone and RAAS activity?

    <p>Chronically increased sympathetic tone</p> Signup and view all the answers

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