The Sympathetic Vasoconstrictor Mediator

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30 Questions

Which blood vessels have the lowest pressure and vascular resistance?

Pulmonary veins

What is the primary goal of the pulmonary circulation?

To carry oxygen from the lungs to the tissues

Which blood vessel receives output from the left ventricle?

Aorta

What is the purpose of blood flow redistribution during exercise?

To direct blood to areas with greater metabolic need

Which layer of blood vessels is composed of concentric layers of smooth muscle cells?

Tunica media

Which type of blood vessels have uniquely thin walls composed of only endothelial cells and basement membrane?

Capillaries

What is the primary site of systemic vascular resistance in the circulatory system?

Arterioles

What is the relationship between wall tension (T), pressure (P), and radius (r) in blood vessels?

T = P/r

Which of the following is the main factor controlling vascular resistance on a minute-to-minute basis?

Radius of the vessel

Which site represents the primary site of vascular resistance maintaining normal blood pressure?

Resistance arterioles

Which of the following hormones is responsible for vasoconstriction and increasing blood pressure?

Angiotensin II

Which endothelium-derived vasodilator plays a role in maintaining normal blood flow?

Prostacyclin (PGI2)

Which mediator is responsible for preventing orthostatic hypotension?

Epinephrine

Which mediator is primarily responsible for sodium and blood volume regulation?

Angiotensin II

Which mediator plays a major role in water conservation by the kidneys?

Vasopressin

Which mediator is released from white blood cells in the process of inflammatory responses?

PGD2

Which hypothesis of autoregulation suggests that decreased pressure and flow result in buildup of vasodilator metabolites that produce vasodilation, while increased pressure and flow wash out vasodilator metabolites, producing vasoconstriction?

Metabolic hypothesis

What is the key regulator of adrenal aldosterone secretion?

Angiotensin II

Which receptor is activated by vasopressin (AVP) to cause vasoconstriction?

V1

Which second messenger is involved in the vasodilation mediated by nitric oxide (NO)?

cGMP

According to the Law of Laplace, which of the following occurs when the arterial wall weakens in response to increased pressure?

Aneurysm

Which type of blood vessels are less compliant than veins but are subjected to greater pressure changes as they receive the stroke volume of the heart during systole?

Arteries

Which blood vessels contain an abundance of elastic fibers that stretch during systole and return to their original shape and size during diastole?

Arteries

Which of the following is the most important biochemical mediator produced by endothelial cells and smooth muscle layers, promoting vasodilation, maintaining vessel patency, and lowering blood pressure?

Nitric oxide (NO)

Which of the following is the most likely cause of the 32-year-old female's fainting spell?

Increased firing of parasympathetic fibers to the heart

Which of the following baroreflex compensatory responses will not occur in response to an acute drop in blood pressure?

Increased firing of sympathetic nerves to the kidney stimulating renin release

Which of the following is a possible cause of primary hypertension?

Coarctation of the aorta

Which of the following is a possible cause of secondary hypertension?

Renal disease

Which of the following hypotheses of origin for hypertension predicts vasoconstriction by generalized autoregulation?

Initial defect in sodium and water retention

Which of the following hypotheses of origin for hypertension involves increased sympathetic tone and RAAS activity?

Chronically increased sympathetic tone

Test your knowledge on the major functions and regulatory mechanisms of the sympathetic vasoconstrictor mediator in the body. Explore how it plays a role in resistance and regulation in both health and disease. Learn about the circadian rhythm of blood levels, its impact on blood pressure, and the role of epinephrine in preventing orthostatic hypotension.

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