Questions and Answers
What is the SOS response and what happens during it?
The SOS response is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis is induced. During the SOS response, the RecA protein is stimulated by single-stranded DNA, leading to the inactivation of the repressor (LexA) of SOS response genes and the induction of the response.
Who discovered the SOS response?
Evelyn Witkin articulated the SOS response.
What was the significance of the discovery of the SOS response?
The SOS response was significant because it was the first coordinated stress response to be elucidated.
What is the role of the RecA protein in the SOS response?
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What is the function of the LexA repressor protein during normal growth?
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