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The Science of Longevity

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Questions and Answers

What is the estimated contribution of genetics to our lifespan?

Approximately 10%.

What is the definition of exceptional old age?

Individuals who belong to the top 10% survivors of their birth cohort.

What is one method used to study the genetic component of longevity?

Genome-wide association studies (GWAS).

What is the main challenge in identifying genetic variants associated with exceptional old age?

The relatively small sample sizes of the studies. Signup and view all the answers

Why are individuals who live to an exceptional old age of interest to scientists?

They are likely to pass on their longevity as an inherited genetic trait. Signup and view all the answers

What is the focus of the Regeneron Genetics Center (RGC)?

Accelerating discoveries by reducing friction between data and insights. Signup and view all the answers

What is one of the strengths of machine learning and AI?

They are extremely powerful and good at solving certain classes of problems. Signup and view all the answers

What is the perspective of the RGC on machine learning and artificial intelligence (AI)?

A data perspective, where clean and well-structured data is essential for effective learning. Signup and view all the answers

What is one of the limitations of machine learning and AI?

They are really bad at solving certain classes of problems. Signup and view all the answers

What is the goal of ensuring clean and well-structured data for machine learning and AI?

To enable these methods to learn and build informative models. Signup and view all the answers