Anticaries, antiplaque, anti-gingivitis agents INFLAM

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Questions and Answers

Which concentration of topical fluoride provides a driving force to penetrate the dental biofilm and concentrate it into areas with early lesions?

  • 5000 ppm
  • 1000 ppm
  • <2500 ppm
  • >2500 ppm (correct)

What is the main mechanism of action of topical fluoride on enamel?

  • Decrease in demineralization and increase in remineralization (correct)
  • Decrease in remineralization
  • Decrease in both demineralization and remineralization
  • Increase in demineralization

How does higher concentrations of fluoride affect the retention of fluoride in the oral cavity?

  • Higher concentrations have no effect on the retention
  • Higher concentrations cause immediate excretion
  • Higher concentrations decrease the retention
  • Higher concentrations prolong the retention (correct)

What is the possible antibacterial effect of fluoride?

<p>Inhibiting the bacterial enzyme, enolase (C)</p> Signup and view all the answers

Why does fluorapatite resist acid degradation better than biologic enamel?

<p>Fluorapatite resists acid degradation better than biologic enamel (B)</p> Signup and view all the answers

Which of the following is a potential consequence of fluoride toxicity on bone?

<p>Increased osteoblast activity (B)</p> Signup and view all the answers

How does excess fluoride (fluoride toxicity) affect the organization of newly laid down bone?

<p>It becomes disorganized (A)</p> Signup and view all the answers

What effect can fluoride have on the release of PTH from the parathyroid gland?

<p>It increases PTH release (D)</p> Signup and view all the answers

What is a potential consequence of increased PTH release caused by fluoride?

<p>Increased bone resorption (B)</p> Signup and view all the answers

How can fluoride affect the susceptibility to osteoporosis in the elderly?

<p>It increases the susceptibility (B)</p> Signup and view all the answers

What is a potential risk associated with fluoride toxicity on bone?

<p>Increased bone brittleness (B)</p> Signup and view all the answers

What can fluoride toxicity on bone lead to over time?

<p>Increased bone fractures (C)</p> Signup and view all the answers

What is the potential cosmetic treatment for fluorosis?

<p>Both tooth bleaching and veneers placement (A)</p> Signup and view all the answers

What is the usual intake of fluoride per day?

<p>1-3 mg (C)</p> Signup and view all the answers

What is the lethal dose of fluoride per day?

<p>5-10 grams (D)</p> Signup and view all the answers

How does acute toxicity of fluoride occur?

<p>All of the above (D)</p> Signup and view all the answers

Which group is recommended to see a dentist every 3 months for evaluation of oral health?

<p>Diabetics (B)</p> Signup and view all the answers

What can periodontal disease cause in pregnant women?

<p>Pre-term labor (C)</p> Signup and view all the answers

Which patients can develop gingivitis due to herpes simplex virus (HSV)?

<p>HIV patients (A)</p> Signup and view all the answers

What is a possible consequence of using medications like anti-convulsants and cyclosporine and calcium channel blocking drugs?

<p>Overgrowth of gingiva (C)</p> Signup and view all the answers

When can anti-plaque mouthwashes be used to replace mechanical toothbrushing?

<p>All of the above (D)</p> Signup and view all the answers

What can periodontal disease contribute to in diabetics?

<p>Hyperglycemia (C)</p> Signup and view all the answers

Which patients may require the use of acyclovir for oral lesions?

<p>HIV patients (A)</p> Signup and view all the answers

Which type of toothbrush would be better suited for mentally or physically-handicapped patients who are unable to brush their teeth themselves?

<p>Electric toothbrush (A)</p> Signup and view all the answers

When should an ultrasonic toothbrush be used transiently?

<p>After subgingival scaling and root planing (C)</p> Signup and view all the answers

What is the therapeutic benefit of using anti-plaque mouthwashes for patients with subgingival inflammation?

<p>It has no therapeutic benefit (D)</p> Signup and view all the answers

What is necessary for patients with subgingival inflammation?

<p>Professional cleaning by subgingival scaling and root planing (C)</p> Signup and view all the answers

What should be noted about the use of anti-plaque mouthwashes for patients with subgingival inflammation?

<p>They will not achieve therapeutic benefit (D)</p> Signup and view all the answers

Which of the following is an adjunct therapy for periodontal disease?

<p>Systemic antibiotics (B)</p> Signup and view all the answers

What is the main mechanism of action of benzophenanthridines in dental hygiene products?

<p>Disrupting the bacterial cell wall or membrane (C)</p> Signup and view all the answers

What is the MOA of biguanide antiseptics like chlorhexidine?

<p>Damaging the bacterial cell wall (B)</p> Signup and view all the answers

Which of the following is a characteristic of chlorhexidine?

<p>Poor absorption by the GI tract (B)</p> Signup and view all the answers

Which of the following is a potential consequence of fluoride toxicity on bone?

<p>Increased PTH release (D)</p> Signup and view all the answers

Which of the following is a common side effect of chlorhexidine rinse?

<p>Formation of a brown extrinsic stain on the teeth and tongue (B)</p> Signup and view all the answers

What is the recommended waiting time after brushing the teeth before using a chlorhexidine rinse?

<p>30 minutes (A)</p> Signup and view all the answers

Which of the following is NOT a side effect of chlorhexidine rinse?

<p>Ingestion of chlorhexidine by a small child (C)</p> Signup and view all the answers

What can ingestion of chlorhexidine by a small child result in?

<p>Gastric distress (D)</p> Signup and view all the answers

Which of the following is a possible side effect of chlorhexidine rinse?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following products contains chlorhexidine?

<p>All of the above (D)</p> Signup and view all the answers

How often should Peridex® rinse be used?

<p>Twice daily (B)</p> Signup and view all the answers

What is the recommended duration of use for chlorhexidine in normal periodontal patients?

<p>Up to 2 weeks (B)</p> Signup and view all the answers

Which antiseptic has anti-inflammatory activity due to its anti-oxidative activity?

<p>Phenolic antiseptics (A)</p> Signup and view all the answers

Why should patients using chlorhexidine avoid tea, coffee, and red wine?

<p>They can cause staining of the teeth (C)</p> Signup and view all the answers

Which antiseptic is less effective than chlorhexidine due to having only one cationic site?

<p>Cetylpyridinium chloride (B)</p> Signup and view all the answers

What can high concentrations of cetylpyridinium chloride (CPC) over time induce?

<p>Staining of the teeth (A)</p> Signup and view all the answers

Which antiseptic has a poor effect in plaque inhibition?

<p>Cetylpyridinium chloride (C)</p> Signup and view all the answers

Which antiseptic is a prototypical example of phenolic antiseptics?

<p>Listerine® (C)</p> Signup and view all the answers

Which enzyme does triclosan block to inhibit fatty acid synthesis?

<p>ENR enzyme (D)</p> Signup and view all the answers

Which of the following is a potential concern associated with the use of triclosan?

<p>Endocrine disruption (B)</p> Signup and view all the answers

What is the mode of action of oxygenating agents?

<p>Producing ROS and degrading protein and nucleic acids (B)</p> Signup and view all the answers

What should be avoided in children or those with alcohol addiction?

<p>Alcohol-containing mouthwashes (D)</p> Signup and view all the answers

What is the suggested mode of action of delmopinol?

<p>Inhibiting bacterial adherence to the tooth (A)</p> Signup and view all the answers

What is the potential issue with prolonged use of iodophors?

<p>Iodine sensitivity (B)</p> Signup and view all the answers

What is the mode of action of halogens and halogen-releasing compounds?

<p>Degrading protein and nucleic acids (B)</p> Signup and view all the answers

What is the active ingredients in several antiplaque or anti-gingivitis agent?

<p>Chlorophors (C)</p> Signup and view all the answers

Which antibiotic is typically used as an adjunct to scaling and root planing for untreated chronic periodontitis?

<p>Amoxicillin (A)</p> Signup and view all the answers

Which antibiotic can serve as an alternative for those with allergies to penicillin or penicillin-resistant infections?

<p>Clindamycin (C)</p> Signup and view all the answers

Which antibiotic blocks cell wall synthesis in Gram+ bacteria and is useful for prevention of dental plaque after periodontal surgery?

<p>Vancomycin (C)</p> Signup and view all the answers

Which mouth rinse is recommended for those who cannot brush their teeth?

<p>Chlorhexidine (C)</p> Signup and view all the answers

In addition to antibiotics, what is another important factor in the treatment of infected tissue?

<p>Proper drainage (C)</p> Signup and view all the answers

Which patients may require the use of antibiotics in dental treatment?

<p>Immunocompromised patients (D)</p> Signup and view all the answers

Which antibiotic can be used as an alternative for those with allergies to penicillin or penicillin-resistant infections?

<p>Clindamycin (C)</p> Signup and view all the answers

Which antibiotic is a glycopeptide antibiotic that blocks cell wall synthesis in Gram+ bacteria?

<p>Vancomycin (B)</p> Signup and view all the answers

Which of the following is the suggested mode of action of delmopinol?

<p>Inhibiting bacterial adherence to the tooth (D)</p> Signup and view all the answers

What is the typical first line treatment for untreated chronic periodontitis, used as an adjunct to scaling and root planing?

<p>Amoxicillin (C)</p> Signup and view all the answers

Which is the best procedure for disrupting dental biofilm?

<p>Mechanical toothbrushing with fluoride-based toothpastes (D)</p> Signup and view all the answers

What is the role of fluoride in treating dental caries?

<p>It resists acid degradation compared to calcium hydroxyapatite. (A)</p> Signup and view all the answers

What is the main reason why antibiotics may not be useful if the tissue has become necrotic?

<p>The antibiotic cannot reach the site of infection (D)</p> Signup and view all the answers

When should systemic antibiotics be used in dental treatment?

<p>As an adjunctive to tooth scaling and root planing (D)</p> Signup and view all the answers

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