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The Mitochondrion in Cancer

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Questions and Answers

Which of the following is a characteristic of cancer cells in relation to mitochondrial functions?

Cancer cells have a lower rate of mitochondrial fission

Cancer cells have a higher rate of mitochondrial biogenesis (correct)

Cancer cells have a lower rate of mitochondrial DNA replication

Cancer cells have a higher rate of mitochondrial fusion

Which of the following is a target for anticancer therapy in glycolytic tumors?

Sirt1 inhibitors

Mitochondrial fission inducers

Hexokinase-2 inhibitors (correct)

PGC1a activators

What is the role of dichloroacetate (DCA) in relation to mitochondrial diseases?

DCA stimulates mitochondrial biogenesis

DCA promotes mitochondrial fusion

DCA enhances mitochondrial DNA replication

DCA inhibits metabolic pathways (correct)

Which axis is involved in stimulating mitochondrial biogenesis?

<p>AMPK-PGC1a axis</p> Signup and view all the answers

What is the main focus of mitochondrial-driven therapeutics?

<p>Targeting antioxidants to mitochondria</p> Signup and view all the answers

The Mitochondrion in Cancer

Choose a study mode

Podcast

Questions and Answers

Which of the following is a characteristic of cancer cells in relation to mitochondrial functions?

Which of the following is a target for anticancer therapy in glycolytic tumors?

What is the role of dichloroacetate (DCA) in relation to mitochondrial diseases?

Which axis is involved in stimulating mitochondrial biogenesis?

What is the main focus of mitochondrial-driven therapeutics?

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