The Integumentary System (PHC411)
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Questions and Answers

What condition is characterized by thinning of hair or baldness?

  • Alopecia (correct)
  • Seborrheic dermatitis
  • Melanoma
  • Hirsutism
  • What is the average growth rate of nails per week?

  • 2 mm
  • 1.5 mm
  • 0.5 mm
  • 1 mm (correct)
  • What type of sweat gland is responsible for emotional sweating?

  • Ceruminous glands
  • Eccrine glands
  • Sebaceous glands
  • Apocrine glands (correct)
  • Which of the following substances is NOT secreted by sebaceous glands?

    <p>Ammonia</p> Signup and view all the answers

    What is the primary function of ceruminous glands?

    <p>Producing earwax</p> Signup and view all the answers

    The nail matrix is important because it does what?

    <p>Produces new nail cells</p> Signup and view all the answers

    Which type of sweat gland is most numerous in the skin?

    <p>Eccrine glands</p> Signup and view all the answers

    What characterizes hirsutism?

    <p>Excessive hairiness</p> Signup and view all the answers

    What part of the hair is responsible for hair growth?

    <p>Follicle</p> Signup and view all the answers

    Which stage of hair growth lasts approximately 2-6 years?

    <p>Growth stage</p> Signup and view all the answers

    What is the primary composition of the cortex of hair?

    <p>Layers of elongated keratinized cells</p> Signup and view all the answers

    What is the function of the papilla in the hair follicle?

    <p>Nourish the growing hair follicle</p> Signup and view all the answers

    What type of hair is described as fine, nonpigmented, downy hairs that cover the body of a fetus?

    <p>Lanugo</p> Signup and view all the answers

    What happens during the regression stage of hair growth?

    <p>Cells of hair matrix stop dividing and shrink</p> Signup and view all the answers

    What component beneath the hair root is responsible for producing the internal root sheath?

    <p>Epithelial root sheath</p> Signup and view all the answers

    Which type of cells is most abundant in the epidermis and synthesizes keratin?

    <p>Keratinocytes</p> Signup and view all the answers

    How is hair color primarily determined?

    <p>Amount and type of melanin</p> Signup and view all the answers

    What is the primary function of melanocytes in the epidermis?

    <p>Synthesize melanin</p> Signup and view all the answers

    Where are Dendritic (Langerhans) cells primarily found in the epidermis?

    <p>Stratum spinosum and stratum granulosum</p> Signup and view all the answers

    What type of epithelium is the epidermis primarily composed of?

    <p>Keratinized stratified squamous epithelium</p> Signup and view all the answers

    Which layer of the epidermis contains the stem cells?

    <p>Stratum basale</p> Signup and view all the answers

    What is the primary function of the stratum corneum?

    <p>To provide a barrier against injury and microbial invasion</p> Signup and view all the answers

    If a large layer of the epidermis is destroyed, what process may be required for regeneration?

    <p>Skin graft</p> Signup and view all the answers

    Which layer of the epidermis is primarily responsible for keratinization?

    <p>Stratum basale</p> Signup and view all the answers

    What is the primary characteristic of keratin that relates to its function?

    <p>Offers protection due to its toughness</p> Signup and view all the answers

    What characterizes the stratum lucidum?

    <p>It consists of flattened clear, dead keratinocytes.</p> Signup and view all the answers

    What is the role of tactile (Merkel) cells in the epidermis?

    <p>Detect touch sensations</p> Signup and view all the answers

    What is the primary composition of the dermis?

    <p>Dense irregular connective tissue and collagen</p> Signup and view all the answers

    Which statement about psoriasis is correct?

    <p>It results in the abnormal production of keratin.</p> Signup and view all the answers

    What type of connective tissue is found in the papillary region of the dermis?

    <p>Loose areolar connective tissue</p> Signup and view all the answers

    Which epidermal layer is made up of dead, scaly cells that are continuously exfoliated?

    <p>Stratum corneum</p> Signup and view all the answers

    What is the effect of constant friction on the stratum corneum?

    <p>Increases cell and keratin production</p> Signup and view all the answers

    What is the primary purpose of fingerprints?

    <p>Used for identifying individuals due to their uniqueness.</p> Signup and view all the answers

    What role do melanocytes play in skin color?

    <p>They produce melanin in melanosomes.</p> Signup and view all the answers

    How does exposure to UV light affect melanin production?

    <p>It increases enzymatic activity leading to more melanin production.</p> Signup and view all the answers

    Which factor is primarily responsible for skin color variations among individuals?

    <p>The amount and distribution of melanin.</p> Signup and view all the answers

    What is the role of melanin in the skin?

    <p>It absorbs UV radiation and prevents DNA damage.</p> Signup and view all the answers

    Which of the following describes the difference between dark and light skin?

    <p>Melanin in dark skin breaks down more slowly than in light skin.</p> Signup and view all the answers

    What characterizes the subcutaneous layer in relation to drug absorption?

    <p>It provides a moderate blood supply that impacts drug absorption rates.</p> Signup and view all the answers

    What is the purpose of using lipid-soluble solvents in transdermal drug administration?

    Signup and view all the answers

    What is the primary method of thermoregulation during exercise in warm environments?

    <p>Increasing sweat secretion from eccrine glands</p> Signup and view all the answers

    How does the skin contribute to protection against microbes?

    <p>By releasing oils that kill bacteria</p> Signup and view all the answers

    Which process assists in the synthesis of Vitamin D in the skin?

    <p>Absorption of UV rays and modification by enzymes in the liver and kidney</p> Signup and view all the answers

    What is one of the main functions of keratin in the skin?

    <p>To provide structure and protect against abrasion</p> Signup and view all the answers

    What change occurs in the body during vasodilation in the skin?

    <p>Increased blood flow to the skin's surface</p> Signup and view all the answers

    What is a determining factor in the type of wound healing that occurs?

    <p>Depth of the injury</p> Signup and view all the answers

    Which of the following is not a cutaneous sensation provided by the skin?

    <p>Emotional response</p> Signup and view all the answers

    What role do Langerhans cells play in skin protection?

    <p>They alert the immune system to pathogens</p> Signup and view all the answers

    What is the significance of melanin in the skin?

    <p>It absorbs UV rays and prevents damage to DNA.</p> Signup and view all the answers

    How do the melanin granules in dark-skinned individuals differ from those in light-skinned individuals?

    <p>They are tightly packed and break down more slowly.</p> Signup and view all the answers

    What role do melanocytes play in skin color variability?

    <p>They synthesize melanin which varies by UV exposure.</p> Signup and view all the answers

    What is the function of melanosomes in melanocytes?

    <p>To synthesize and store melanin.</p> Signup and view all the answers

    What characteristic of the subcutaneous layer affects drug absorption?

    <p>It provides stabilization for the skin relative to underlying tissues.</p> Signup and view all the answers

    Why do fingerprints remain unchanged throughout a person's life?

    <p>They are created by the interaction of specific skin layers.</p> Signup and view all the answers

    Which statement correctly describes the absorption characteristics of transdermal drug administration?

    <p>Lipid-soluble solvents are used to increase drug absorption through the skin.</p> Signup and view all the answers

    What factor primarily affects the enzymatic activity of melanocytes in the synthesis of melanin?

    <p>Exposure to UV light.</p> Signup and view all the answers

    Study Notes

    The Integumentary System (PHC411)

    • The integumentary system encompasses the skin, hair, and nails.
    • The system's structure is crucial for its function.
    • Skin has 3 main layers: epidermis, dermis, and hypodermis.
    • The epidermis is the outermost protective layer composed of stratified squamous epithelium.
    • The dermis is the middle layer, thick, dense irregular connective tissue containing collagen and elastic fibers.
    • The hypodermis is the deepest layer which consists of areolar connective tissue and adipose tissue.
    • Skin also has four major cells: keratinocytes, melanocytes, Langerhans cells, and Merkel cells.
    • Epidermal cells include the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale.
    • Skin color is primarily due to melanin, produced by melanocytes.
    • Skin also contains sebaceous and sweat glands to control body temperature.
    • Hair structures include the follicle, shaft, root, cuticle, cortex, medulla and papilla.
    • Nails are made of hard keratinized epidermal cells found on the dorsal surfaces of fingers and toes.

    Skin Structure

    • Epidermis (superficial): Composed of epithelial tissue, avascular, several layers.
    • Dermis (middle): Thick, dense irregular connective tissue, richer blood supply, contains capillaries and nerve endings.
    • Hypodermis (deepest ): Contains adipose tissue and blood vessels, more fat than other layers.

    Skin Cells

    • Keratinocytes: Majority, synthesize keratin for protection and structure.
    • Melanocytes: Synthesize melanin for UV protection, located in stratum basale and spinosum layers.
    • Dendritic Cells (Langerhans): Immune system cells, found in stratum spinosum and granulsum, migrate to lymph nodes.
    • Merkel Cells: Sensory receptors, found in stratum basale, involved in touch and pressure sensations.

    Skin Color

    • Melanin: Pigment produced by melanocytes, responsible for most of the variation in skin color, affects UV protection.
    • Hemoglobin: Red pigment of red blood cells, responsible for reddish coloration.
    • Carotene: Yellow-orange pigment of vegetables and egg yolks, Concentrated in the stratum corneum and hypodermis.
    • Skin color is an important indicator of certain medical conditions like Jaundice or abnormalities like Vitiligo.

    Skin Glands

    • Sebaceous glands: Associated with hair follicles, secrete sebum (oily substance), prevents hair and skin dehydration, and prevents bacterial growth.
    • Sudoriferous glands: include eccrine sweat glands (most numerous, water perspiration) and apocrine sweat glands (produce thicker sweat, in certain areas like groin).

    Functions of Skin

    • Protection: Prevents dehydration, protects against UV radiation, chemicals, and injury.
    • Thermoregulation: Releases sweat for evaporation, and vessels dilate or constrict for heat distribution.
    • Sensation: Detects touch, pressure, temperature, and pain.
    • Excretion: Eliminates waste products through sweat.
    • Vitamin D synthesis: Synthesizes Vitamin D in response to UV radiation.
    • Reservoir: Blood vessels carry a significant volume of blood (8-10%).

    Wound Healing

    • Epidermal wound healing: Occurs in superficial wounds, returns to normal function.
    • Deep wound healing: Occurs when the dermis is injured, loss of function, scarring is likely.

    Burns

    • Classification: First-degree, second-degree, and third-degree burns, based on depth of damage.
      • First degree: Involves epidermis only.
      • Second degree: Damage to epidermis and some dermis.
      • Third degree: Destroys epidermis, dermis, and subcutaneous layers.
    • Severity: Classified by the extent and depth of tissue damage.
    • Treatment: Varies based on the severity of the burn injury.

    Skin Cancer

    • Risk factors: Exposure to UV radiation from the sun, being fair-skinned, age.
    • Types: Basal cell carcinoma, squamous cell carcinoma, malignant melanoma.

    Common Skin Disorders

    • Conditions like Alopecia, Hirsutism, Dermatitis, Eczema, Folliculitis, Herpes, Shingles, Impetigo, Psoriasis, Ringworm, Scabies, Warts and others.

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    Related Documents

    The Integumentary System PDF

    Description

    Explore the intricacies of the integumentary system, including its structure and function. Discover the layers of the skin, key cells involved, and the roles of hair and nails. This quiz will test your knowledge on essential concepts related to this vital system.

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