The Extrinsic Pathway of Apoptosis Quiz

It upregulates the expression of death receptors Fas and DR5

It activates downstream executioner caspases directly

It binds to Fas on the target cell, leading to the formation of a death-inducing signaling complex (correct)

It competes with death receptors for ligand binding, inhibiting apoptosis

It competes with caspase 8 and caspase 10 for binding site in the DISC (correct)

It inhibits the binding of Fas ligand to Fas receptors

It upregulates the expression of death receptors Fas and DR5

It directly activates downstream executioner caspases

To amplify the caspase cascade and induce apoptosis (correct)

To inhibit the formation of the death-inducing signaling complex

To directly activate initiator caspases

To compete with death receptors for ligand binding

<p>They compete with death receptors for ligand binding, inhibiting ligand-induced apoptosis</p> Signup and view all the answers

<p>It binds intracellular adaptor proteins, which in turn bind initiator caspases</p> Signup and view all the answers