6.3

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Questions and Answers

What happens when a person receives blood from a donor with a different blood type?

  • The donor's blood becomes incompatible
  • The recipient's blood type changes
  • Agglutination occurs (correct)
  • The immune system strengthens

Individuals with blood type O will show clumping in both Anti-A and Anti-B fields.

False (B)

What is the significance of the Rhesus factor in blood types?

It determines if blood is Rhesus positive (Rh+) or Rhesus negative (Rh-) based on the presence of Antigen D.

O negative individuals are known as the ______ donors.

<p>universal</p> Signup and view all the answers

Match the following blood types to their corresponding clumping reactions:

<p>Type A = Clumps in Anti-A field Type B = Clumps in Anti-B field Type AB = Clumps in both Anti-A and Anti-B fields Type O = No clumps appear</p> Signup and view all the answers

What substance is released by platelets and damaged cells during the blood clotting process?

<p>Thromboplastin (C)</p> Signup and view all the answers

Blood type O cells contain both A and B antigens on their surface.

<p>False (B)</p> Signup and view all the answers

What is the role of fibrin in the blood clotting process?

<p>To form a sticky mesh-like network that helps trap blood cells and platelets.</p> Signup and view all the answers

The process of breaking down a fibrin clot is called ____.

<p>fibrinolysis</p> Signup and view all the answers

Match the blood types with their corresponding plasma antibodies.

<p>Type A = Antibody B Type B = Antibody A Type AB = No antibodies Type O = Antibodies A and B</p> Signup and view all the answers

Which component converts prothrombin into thrombin during the coagulation cascade?

<p>Thromboplastin (C)</p> Signup and view all the answers

Agglutination is a process that occurs when antibodies bind to antigens in blood typing.

<p>True (A)</p> Signup and view all the answers

What is the primary function of leukocytes?

<p>Fight against infection (D)</p> Signup and view all the answers

Thrombocytes are involved in the immune response of the body.

<p>False (B)</p> Signup and view all the answers

What condition is characterized by a lack of iron?

<p>Anemia</p> Signup and view all the answers

The average ratio of white blood cells to red blood cells is _____ to 1.

<p>700</p> Signup and view all the answers

Match the types of white blood cells with their functions:

<p>Neutrophils = Kill bacteria and fungi Lymphocytes = Protect against viral infections Eosinophils = Identify parasites and cancer cells Monocytes = Clean up damaged cells</p> Signup and view all the answers

All thrombocytes are identical in shape and size.

<p>False (B)</p> Signup and view all the answers

What enzyme is released by platelets to initiate the clotting process?

<p>The specific enzyme is not mentioned, but it refers to various clotting factors.</p> Signup and view all the answers

Flashcards

Blood type clumping

Blood type clumping occurs when antibodies in the blood react with antigens on red blood cells, causing them to clump together.

Blood type O

Blood type O has no A or B antigens on its red blood cells, making it a universal donor.

Rhesus factor

Rhesus factor is a specific antigen (protein) on red blood cells.

Rh+

Rh+ blood type indicates the presence of the Rhesus factor (Antigen D) on red blood cells.

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Rh- pregnancy complication

If an Rh- mother carries an Rh+ baby, the mother's immune system may attack the baby's blood cells in subsequent pregnancies, leading to serious complications.

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Blood Clotting

A biological process that stops bleeding by forming a clot at the site of injury.

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Platelets

Small, cell-like fragments in blood that clump together at injury sites to form a temporary plug and release clotting factors.

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Thromboplastin

A substance released by platelets and damaged cells that triggers the conversion of prothrombin to thrombin, initiating the clotting cascade.

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Prothrombin

An inactive protein produced by the liver that is converted to thrombin by thromboplastin, playing a crucial role in clotting.

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Thrombin

An active enzyme created from prothrombin that converts fibrinogen to fibrin, forming a mesh-like network for the clot.

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Fibrinogen

An inactive protein produced by the liver, converted to fibrin by thrombin, forming a mesh-like network that traps blood cells and platelets to create a clot.

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Fibrin

A sticky protein formed from fibrinogen that creates a mesh-like network to trap blood cells and platelets during clot formation.

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Fibrinolysis

The breakdown of a fibrin clot by the enzyme plasmin, allowing for blood vessel repair and restoring normal blood flow.

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Hemoglobin's role

Hemoglobin, a protein in red blood cells, binds to oxygen in the lungs and releases it in tissues.

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Red blood cell count

A typical red blood cell contains approximately 200 million hemoglobin molecules.

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Anemia

Anemia signifies a lack of iron, a crucial component of hemoglobin, which is essential for oxygen transport.

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Red blood cells' function

Red blood cells help keep blood liquid, reducing the workload for the heart.

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Leukocytes and their function

White blood cells (leukocytes) are larger than red blood cells and play a crucial role in the immune system by fighting infections.

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Types of leukocytes

White blood cells come in various types, including neutrophils, lymphocytes, eosinophils, basophils, and monocytes, each with specific roles in fighting infections.

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Platelet function

Platelets, tiny fragments of cells, play a crucial role in blood clotting, preventing excessive blood loss.

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Hemophilia

Hemophilia represents an inability for the blood to clot properly, leading to excessive bleeding.

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Study Notes

The Circulatory System: Blood

  • Blood is a specialized body fluid in circulatory systems, delivering oxygen and nutrients, and removing carbon dioxide and wastes.
  • Blood is primarily water with dissolved substances, proteins, and other components for efficient transport.
  • Blood is composed of two main parts:
    • Plasma (55%):
      • Primarily water (90%)
      • Plasma proteins, hormones, nutrients, dissolved gases, salts, and waste products.
    • Formed elements (45%):
      • Buffy coat (white blood cells and platelets)
      • Hematocrit (red blood cells)

Blood Cells

  • Three main types:
    • Erythrocytes (red blood cells):
      • Live about 120 days.
      • Produced in red bone marrow (e.g., skull, ribs, vertebrae, long bones).
      • Biconcave shape, no nucleus.
      • Contain hemoglobin, which carries oxygen and carbon dioxide.
      • Approximately 200,000,000 hemoglobin molecules per red blood cell.
      • Anemia results from iron deficiency.
    • Leukocytes (white blood cells):
      • Larger than red blood cells.
      • Produced in bone marrow and lymphatic system (e.g., thymus).
      • Have nuclei, no defined shape.
      • Outnumber red blood cells 700:1.
      • Function in fighting infection as part of the immune system.
      • Different types (neutrophils, lymphocytes, eosinophils, basophils, monocytes) with varied functions. Phagocytic—digest invaders.
    • Thrombocytes (platelets):
      • Small fragments of cells.
      • Produced in bone marrow.
      • Essential for blood clotting.
      • Release enzymes to promote blood clotting, without them uncontrolled bleeding occurs.
      • Hemophilia is a clotting disorder.
  • Blood clotting cascade:
    • Platelets clump at damaged sites.
    • Thromboplastin activates a cascade of reactions.
    • Prothrombin converts to thrombin.
    • Thrombin activates fibrinogen to form fibrin (a clot).
    • Plasmin dissolves the clot after healing (fibrinolysis).

Blood Types

  • Blood types are categorized by antigens on red blood cells and antibodies in the plasma.
  • Four main blood types: A, B, AB, and O.
  • Antigens (A or B) are present on the cell surface in different combinations.
  • Antibodies (anti-A, anti-B) are present in the plasma, reacting with matching antigens.
  • Blood transfusions must match blood types to avoid agglutination (clumping).
  • Universal donor is O negative, universal recipient is AB positive.

Rhesus Factor

  • An additional antigen (Rh factor, Antigen D) on red blood cells.
  • Rh+ individuals have the antigen, Rh- individuals lack it.
  • Mismatched Rh factor during pregnancy can cause complications in subsequent pregnancies.
  • Prenatal testing and medication (RhoGAM) can prevent problems.

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